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실리콘 오일을 유방에 주입한 후에 발생한 지방성 폐렴 1예

A Case of Lipoid Pneumonia Associated with Silicon Oil Injection into Breast

  • 최재현 (충북대학교 의학전문대학원 충북대학교병원 내과학교실) ;
  • 김미경 (충북대학교 의학전문대학원 충북대학교병원 내과학교실) ;
  • 박재근 (충북대학교 의학전문대학원 충북대학교병원 내과학교실) ;
  • 박용근 (청주 성모병원 내과) ;
  • 최강현 (충북대학교 의학전문대학원 충북대학교병원 내과학교실) ;
  • 이기만 (충북대학교 의학전문대학원 충북대학교병원 내과학교실) ;
  • 안진영 (충북대학교 의학전문대학원 충북대학교병원 내과학교실)
  • Choi, Jae-Hyeon (Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine) ;
  • Kim, Mi-Kyoung (Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine) ;
  • Park, Jae-Geun (Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine) ;
  • Park, Yong-Kun (Department of Internal Medicine, The Cheongju St. Mary's Hospital) ;
  • Choi, Kang-Hyeon (Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine) ;
  • Lee, Ki-Man (Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine) ;
  • An, Jin-Young (Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University School of Medicine)
  • 투고 : 2010.05.03
  • 심사 : 2010.06.01
  • 발행 : 2010.10.30

초록

Exogenous lipoid pneumonia occurs rarely in healthy people. In most cases, exogenous lipoid pneumonia is usually caused by aspiration of mineral, vegetable, or animal oil. We report the case of 42-year-old woman, who have experienced lipoid pneumonia after silicon injection into her breast for cosmetic purposes. The patient experienced fever, dyspnea, sputum, and hemoptysis after silicon injection into her breast. Chest computed tomography demonstrated non- segmental distribution of bilateral consolidation in both lung fields. A transbronchial lung biopsy specimen shows foamy microphages in alveolar spaces. Papanicolaous staining of bronchoalveolar lavage fluid showed abundant foamy marcrophages and many neutrophils. With these results, we confirmed lipoid pneumonia was associated with silicon oil injection into breast.

키워드

참고문헌

  1. Gondouin A, Manzoni P, Ranfaing E, Brun J, Cadranel J, Sadoun D, et al. Exogenous lipid pneumonia: a retrospective multicentre study of 44 cases in France. Eur Respir J 1996;9:1463-9. https://doi.org/10.1183/09031936.96.09071463
  2. Spickard A 3rd, Hirschmann JV. Exogenous lipoid pneumonia. Arch Intern Med 1994;154:686-92. https://doi.org/10.1001/archinte.154.6.686
  3. Shin DJ, Park BS, Yang MS, Han HS, Koh YY, Moon HR, et al. Clinical study on lipoid pneumonia caused by aspiration of squalene. J Korean Pediatr Soc 1991; 34:654-61.
  4. Edgerton MT, Wells JH. Indications for and pitfalls of soft tissue augmentation with liquid silicone. Plast Reconstr Surg 1976;58:157-65. https://doi.org/10.1097/00006534-197608000-00004
  5. Coulaud JM, Labrousse J, Carli P, Galliot M, Vilde F, Lissac J. Adult respiratory distress syndrome and silicone injection. Toxicol Eur Res 1983;5:171-4.
  6. Ellenbogen R, Rubin L. Injectable fluid silicone therapy. Human morbidity and mortality. JAMA 1975; 234:308-9. https://doi.org/10.1001/jama.234.3.308
  7. Rodriguez MA, Martinez MC, Lopez-Artiguez M, Soria ML, Bernier F, Repetto M. Lung embolism with liquid silicone. J Forensic Sci 1989;34:504-10.
  8. Chastre J, Basset F, Viau F, Dournovo P, Bouchama A, Akesbi A, et al. Acute pneumonitis after subcutaneous injections of silicone in transsexual men. N Engl J Med 1983;308:764-7. https://doi.org/10.1056/NEJM198303313081307
  9. Barie PS, Malik AB. Role of intravascular coagulation and granulocytes in lung vascular injury after bone marrow embolism. Circ Res 1982;50:830-8. https://doi.org/10.1161/01.RES.50.6.830
  10. Idell S, James KK, Gillies C, Fair DS, Thrall RS. Abnormalities of pathways of fibrin turnover in lung lavage of rats with oleic acid and bleomycin-induced lung injury support alveolar fibrin deposition. Am J Pathol 1989;135:387-99.
  11. Abraham E. Coagulation abnormalities in acute lung injury and sepsis. Am J Respir Cell Mol Biol 2000;22: 401-4. https://doi.org/10.1165/ajrcmb.22.4.f184
  12. Lee KS, Muller NL, Hale V, Newell JD Jr, Lynch DA, Im JG. Lipoid pneumonia: CT findings. J Comput Assist 1995;19:48-51. https://doi.org/10.1097/00004728-199501000-00009
  13. Laurent F, Philippe JC, Vergier B, Granger-Veron B, Darpeix B, Vergeret J, et al. Exogenous lipoid pneumonia: HRCT, MR, and pathologic findings. Eur Radiol 1999;9:1190-6. https://doi.org/10.1007/s003300050815
  14. Silverman JF, Turner RC, West RL, Dillard TA. Bronchoalveolar lavage in the diagnosis of lipoid pneumonia. Diagn Cytopathol 1989;5:3-8. https://doi.org/10.1002/dc.2840050103
  15. Hyun JG, Rhee CH. Clinical investigation of lipoid pneumonia in adults. Tuberc Respir Dis 1996;43:965-75.