Tuberculosis and Respiratory Diseases

  • 제68권3호
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  • Pages.146-154
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  • 2010
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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국내 다제내성 및 광범위내성결핵의 최근 현황

The Recent Status of Multidrug- and Extensively Drug-Resistant Tuberculosis in Korea

  • 김선영 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 김희진 (결핵연구원) ;
  • 김창기 (결핵연구원) ;
  • 윤혜령 (서울의과학연구소) ;
  • 배혜경 (녹십자의료재단) ;
  • 이선화 (네오딘의학연구소) ;
  • 성낙문 (국립마산병원) ;
  • 김대연 (국립목포병원) ;
  • 이강영 (서북병원) ;
  • 조영수 (서북병원) ;
  • 이상도 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 김우성 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 김동순 (울산대학교 의과대학 서울아산병원 호흡기내과학교실) ;
  • 심태선 (울산대학교 의과대학 서울아산병원 호흡기내과학교실)
  • Kim, Sun-Young (Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Hee-Jin (Korean Institute of Tuberculosis) ;
  • Kim, Chang-Ki (Korean Institute of Tuberculosis) ;
  • Yoon, Hye-Ryung (Seoul Medical Science Institute) ;
  • Bae, Hye-Gyung (Green Cross Reference Laboratory) ;
  • Lee, Sun-Hwa (Neodin Medical Institute) ;
  • Sung, Nack-Moon (National Masan Hospital) ;
  • Kim, Dae-Yeon (National Mokpo Hospital) ;
  • Lee, Gang-Young (Seobuk Hospital) ;
  • Cho, Young-Soo (Seobuk Hospital) ;
  • Lee, Sang-Do (Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Woo-Sung (Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Dong-Soon (Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shim, Tae-Sun (Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 투고 : 2010.01.28
  • 심사 : 2010.02.17
  • 발행 : 2010.03.30
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초록

Background: The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has become a serious worldwide problem. However, there is insufficient data regarding the current status of MDR-TB and XDR-TB in Korea. This study examined the recent status of MDR- and XDR-TB using the data from 7 laboratories, in which almost all drug susceptibility tests (DST) for Mycobacterium tuberculosis were performed. Methods: The patients' identification data and DST results were collected from all 7 laboratories from 2001 to 2006 and the number of patients with MDR-TB and XDR-TB were calculated. Results: The number of DSTs was 140,638 for 6 years with an increasing incidence each year (p<0.001). The number of DST with MDR results was 18,510 and personal identifying information was obtained in 16,640 (89.9%) tests. The number of MDR-TB patients from 2001 to 2006 was 2,329, 2,496, 2,374, 2,300, 2,354, and 2,178, respectively, when counting the duplications in a year as one patient. The number of MDR-TB patients when counting the duplications in 6 years as one patient was 2,281, 1,977, 1,620, 1,446, 1,512, and 1,373, respectively. When the same method was adopted, the number of XDR-TB patients was 191, 238, 282, 260, 272, and 264, respectively, and 189, 150, 130, 90, 122, and 110 patients, respectively. Conclusion: Despite the national efforts to control TB, there are still a large number of MDR- and XDR-TB patients in Korea.

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참고문헌

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피인용 문헌

  1. 일개 부산지역 3차 병원에서 관찰한 다제내성 결핵의 실태, 2005~2009 vol.71, pp.2, 2010, https://doi.org/10.4046/trd.2011.71.2.120
  2. The efficacy of rifabutin for rifabutin-susceptible, multidrug-resistant tuberculosis vol.107, pp.2, 2010, https://doi.org/10.1016/j.rmed.2012.10.021