The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
권호 표지

Compliance of Herbal Medicine in Children and the Factors Associated with Compliance

소아(小兒)의 한약 복용 순응도와 영향 요인

  • Lee, Sun-Haeng (Department of Oriental Pediatrics, East West Neo Medical Hospital, Kyung Hee University) ;
  • Chang, Gyu-Tae (Department of Oriental Pediatrics, East West Neo Medical Hospital, Kyung Hee University)
  • 이선행 (경희대학교 동서신의학병원 한방소아과) ;
  • 장규태 (경희대학교 동서신의학병원 한방소아과)
  • Received : 2010.07.23
  • Accepted : 2010.12.13
  • Published : 2010.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: Compliance of herbal medicine is extremely important in Korean oriental medicine, since herbal medicine is main approach to the most of outpatients in Korean pediatrics. The more compliant to the medication, the more effective care is given to children. Thus, we conducted this research to evaluate the compliance of herbal medicine, and factors associated with compliance in children. Methods: 61 children (men 28, women 33) were participated who visited the Korean Oriental Medicine Department in university hospital for two weeks. We used Morisky's self-reported questionnaire which is consisted of four questions. Also, we checked medical records and researched respondent to acquire more factors. We defined as a "full compliant" if answers were 'No' to all of the questions. We analyzed the compliance and associated factors with Pearson's $x^2$-test and Fisher's exact test, and Spearman correlation coefficient. Compliance and associated factors were analyzed with linear regression. Results: Compliance of herbal medicine was not related to respondent, and 34 children (55.7%) were non-compliant. The best compliant type of herbal medicine was granule medication (p=0.046). However, there was no relationship between compliance and age, sex, sibling, purpose of medication, period of disease, frequency of medication, and medication duration. The age, frequency of medication, medication duration, and purpose of medications(period of disease) had correlation(p<0.01). Also, older children tended to forget to take herbal medicine(p=0.004). Conclusions: Over an half of the total subjects (55.7%) were non-compliant, so we should improve compliance of herbal medicine. Since granule form of medication was shown to have the best compliance, we should try to use granule form of medication instead of liquid medications. Also, we can also improve compliance with giving attention to the patients, especially older children in order to improve their compliance.

Keywords

References

  1. 김경철, 김주태, 김지선, 조항석, 심재용, 이혜리. 노인환자의 복약 순응도와 이에 영향을 미치는 요인. 가정의학회지. 1999;20(10):1216-23.
  2. Cramer JA, Rosenheck R : Compliance with medication regimens for mental and physical disorders. Psychiatric Service. 1998;49(2):196-201. https://doi.org/10.1176/ps.49.2.196
  3. World Health Organization. Adherence to Long-Term Therapies : Evidence for Action. Geneva : World Health Organization. 2003.
  4. Evans CE, Haynes RB. Paitient compliance. In : Rakel RE. Editor. Textbook of family practice. 4th ed. Philadelphia : Saunders WB, 1990:371-7.
  5. Buck D, Jacoby A, Baker GA, Chadwick DW. Factors influencing compliance with antiepileptic drug regimens. Seizure. 1997;6:87-93. https://doi.org/10.1016/S1059-1311(97)80060-X
  6. La Graca AM. Issues in adherence with pediatric regimens. J Pediatr Psychol. 1990:15(4);423-36. https://doi.org/10.1093/jpepsy/15.4.423
  7. 최영환, 민기식, 김종완, 간질환아의 항경련제 투약에 대한 순응도 연구. 대한소아과학회지. 1998;41: 1553-8.
  8. 박미정, 남유니, 최덕영, 선용한, 은병욱, 심소연, 조강호, 류일, 손동우, 전인상, 차한. 간질경련을 주소로 내원한 소아 환자의 복약순응도. 대한소아신경학회지. 2009;17(2):159-66.
  9. 서정민, 이상곤, 황순이, 김상찬, 왕향란, 조성언, 백정한. 소아의 한약 복용에 관한 임상적 실태 조사. 대한한방소아과학회지. 2006;20(3):33-50.
  10. Morisky DE, Levine DM, Green LW. Concurrent and predictive validity of a self-reported measures of medication adherence. Med Care. 1986;24:64-74.
  11. 김성원, 이인구, 김미영, 유태우, 허봉렬. 복약 순응도에 관한 자가보고 설문의 한국어판 개발 및 타당도 조사. 가정의학회지. 1995;16(2):172-9.
  12. Stewart RB, Cluff LE. A review of medication errors and compliance in ambulant patient. Clinical pharmacology therapy. 1972;13:463-4. https://doi.org/10.1002/cpt1972134463
  13. Ron J. Anderson, Lynne M. Kirk. Methods of improving Patient Compliance in Chroni Disease States. Arch Intern Med. 1982;142:463-4.
  14. Roth HP. Histological review : comparison with other methods. Control Clin Trials. 1984;5:476-80. https://doi.org/10.1016/0197-2456(84)90007-2
  15. Steiner JF, Koepsell TD, Fihn SD, Inui TS. A general method of compliance assessment using centralized pharmacy records. Description and Validation. Med care. 1988;26:814-23. https://doi.org/10.1097/00005650-198808000-00007
  16. Norell SE. Methods in assessing drug compliance. Acta-Med-Scand-Suppl. 1984;683:36-40.
  17. 조태흠, 진충권, 김윤진. 약물 순응도와 관련된 건강 신념. 가정의학회지. 1995;16(7):470-9.
  18. Jean-Pierre Gregoire, Remi Guibert, Andre Archambault, Andre-Pierre Contandriopoulos. Medication Compliance in a Family Practice. Canadian Family Physician. 1992;38: 2333-7.
  19. Claxton AJ, Cramer J, Pierce C. A systematic review of the associations between dose regimens and medication compliance. Clin Ther. 2001;23:1296-310. https://doi.org/10.1016/S0149-2918(01)80109-0
  20. Sabine Hack, Byron Chow. Pediatric Psychotropic Medication Compliance : A Literature Review and Research-Based Suggestions for Improving Treatment Compliance. Journal of Child and Adolescent Psychopharmacology. 2001;11(1): 59-67. https://doi.org/10.1089/104454601750143465
  21. Bender B, Milgrom H, Rand C, Ackerson L. Psychological factors associated with medication nonadherence in asthmatic children. J Asthma. 1998;35(4): 347-53. https://doi.org/10.3109/02770909809075667
  22. 최현정, 방나영, 송보완, 김남재, 류봉하. 한약제형 선호도에 관한 설문조사. 경희의학. 2004;20(1):46-57.
  23. 이상현, 정유석. 환자교육. 가정의학. 서울 : 계축문화사. 1997:145-50.
  24. Asadi-Pooya AA. Drug compliance of children and adolescents with epilepsy. Seizure. 2005;14:393-5. https://doi.org/10.1016/j.seizure.2005.05.003
  25. Ngoh LN. Health literacy : a barrier to pharmacistpatient communication and medication adherence. J Am Pharm Assoc. 2003;49(5):132-46.
  26. Elliott RA, Marriott JL Standardised assessment of patients' capacity to manage medications : a systematic review of published instruments. BMC Geriatr. 2009;9:27. https://doi.org/10.1186/1471-2318-9-27
  27. Rimer BK, Galnz K, Lerman C. Contributions of Public Health to Patient Compliance. Journal of Community Health. 1991;16(4):225-40. https://doi.org/10.1007/BF01324390
  28. Kyngs H. Predictors of good compliance in adolescents with epilepsy. Seizure. 2001;10:549-53. https://doi.org/10.1053/seiz.2001.0557
  29. Amanda Henry, Robert G. Batey. Enhancing compliance not a prerequisite for effective eradication of H.pylori. The American Journal of Gastroenterology. 1996;94(3):811-6.
  30. Wise MG, Rundell JR. Concise Guide to Consultation Psychiatry. 2nd ed. American Psychiatric Press. Washington. 1994.
  31. Debusk RF, Miller NH, Superko HR, et al. A case-management system for coronary risk factor modification after acute myocardinal infarction. Ann Intern Med. 1994;120:721. https://doi.org/10.7326/0003-4819-120-9-199405010-00001
  32. Buchanan N. Noncompliance with medication amongst persons attending a tertiary referral epilepsy clinic : implications, management and outcome. Seizure. 1993;2:79-82. https://doi.org/10.1016/S1059-1311(05)80107-4
  33. Fotheringham MJ, Sawyer MG. Adherence to recommended medical regimens in childhood and adolescence : A review. J Paediatr Child Health. 1995;31:72-8. https://doi.org/10.1111/j.1440-1754.1995.tb00750.x
  34. Liptak GS. Enhancing paitient compliance in pediatrics. Pediatr Rev. 1996;17:128-34. https://doi.org/10.1542/pir.17-4-128
  35. El-Chaar GM, Mardy G, Wehlou K, Rubin CG. Randomized, double blind comparison of brand and generic antibiotic suspensions : II. A study of taste and compliance in children. Pediatr Infect Dis. 1996;J15: 18-22.
  36. 서정민, 윤혜진, 김상찬, 황순이, 지선영, 조동희, 손지영, 백정한. 신제형의 소아 약물 순응도 조사 - 기존의 제재와 비교하여 복용의 간편성, 맛의 개선도, 운반 및 저장의 편의성 포함 -. 대한한방소아과학회지. 2007;21(3):11-9.
  37. 최남현, 김흥기, 이혜리, 김기순. 고혈압 환자의 순응도에 영향을 미치는 요인에 대한 연구. 가정의학회지. 1991;12(10):1-11.