참고문헌
- Carmeliet, P. : Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6, 389 (2000). https://doi.org/10.1038/74651
- Carmeliet, P. and Jain, R. K. : Angiogenesis in cancer and other diseases. Nature 407, 249 (2000). https://doi.org/10.1038/35025220
- Blagosklonny, M. V. : Antiangiogenic therapy and tumor progression. Cancer. Cell. 5, 13 (2004). https://doi.org/10.1016/S1535-6108(03)00336-2
- Kerbel, R. and Folkman, J. : Clinical translation of angiogenesis inhibitors. Nat. Rev. Cancer 2, 727 (2002). https://doi.org/10.1038/nrc905
- Sternlicht, M. D. and Werb, Z. : How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell. Dev. Biol. 17, 463 (2001). https://doi.org/10.1146/annurev.cellbio.17.1.463
- Stetler-Stevenson, W. G. : Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention. J. Clin. Invest. 103, 1237 (1999). https://doi.org/10.1172/JCI6870
- Baker, A. H., Edwards, D. R. and Murphy, G. : Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J. Cell Sci. 115, 3719 (2002). https://doi.org/10.1242/jcs.00063
- Hoegy, S. E., Oh, H. R., Corcoran, M. L. and Stetler- Stevenson, W. G. : Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition. J. Biol. Chem. 276, 3203 (2001). https://doi.org/10.1074/jbc.M008157200
- Seo, D. W., Li, H., Guedez, L., Wingfield, P. T., Diaz, T., Salloum, R., Wei, B. Y. and Stetler-Stevenson, W. G. : TIMP-2 mediated inhibition of angiogenesis : an MMP-independent mechanism. Cell. 114, 171 (2003). https://doi.org/10.1016/S0092-8674(03)00551-8
- Stetler-Stevenson, W. G. : Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities. Sci. Signal. 1, re6 (2008). https://doi.org/10.1126/scisignal.127re6
- Wingfield, P. T., Sax, J. K., Stahl, S. J., Kaufman, J., Palmer, I., Chung, V., Corcoran, M. L., Kleiner, D. E. and Stetler- Stevenson, W. G. : Biophysical and functional characterization of full-length, recombinant human tissue inhibitor of metalloproteinases-2 (TIMP-2) produced in Escherichia coli. Comparison of wild type and amino-terminal alanine appended variant with implications for the mechanism of TIMP functions. J. Biol. Chem. 274, 21362 (1999). https://doi.org/10.1074/jbc.274.30.21362
- Schwartz, M. A. : Integrin signaling revisited. Trends Cell Biol. 11, 466 (2001). https://doi.org/10.1016/S0962-8924(01)02152-3
- Hynes, R. O. : Integrins: bidirectional, allosteric signaling machines. Cell 110, 673 (2002). https://doi.org/10.1016/S0092-8674(02)00971-6
- Nyberg, P., Xie, L. and Kalluri, R. : Endogenous inhibitors of angiogenesis. Cancer Res. 65, 3967 (2005). https://doi.org/10.1158/0008-5472.CAN-04-2427
- Dixelius, J., Cross, M., Matsumoto, T., Sasaki, T., Timpl, R. and Claesson-Welsh, L. : Endostatin regulates endothelial cell adhesion and cytoskeletal organization. Cancer Res. 62, 1944 (2002).
- Marneros, A. G. and Olsen, B. R. : Physiological role of collagen XVIII and endostatin. FASEB J. 19, 716 (2005). https://doi.org/10.1096/fj.04-2134rev
- Wickstrom, S. A., Alitalo, K. and Keski-Oja, J. : An endostatin-derived peptide interacts with integrins and regulates actin cytoskeleton and migration of endothelial cells. J. Biol. Chem. 279, 20178 (2004). https://doi.org/10.1074/jbc.M312921200
- Kim, Y. M., Hwang, S., Kim, Y. M., Pyun, B. J., Kim, T. Y., Lee, S. T., Gho, Y. S. and Kwon, Y. G. : Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. J. Biol. Chem. 277, 27872 (2002). https://doi.org/10.1074/jbc.M202771200
- Folkman, J. : Antiangiogenesis in cancer therapy-endostatin and its mechanisms of action. Exp. Cell Res. 312, 594 (2006). https://doi.org/10.1016/j.yexcr.2005.11.015
- Lee, S. J., Jang, J. W., Kim, Y. M., Lee, H. I., Jeon, J. Y., Kwon, Y. G. and Lee, S. T. : Endostatin binds to the catalytic domain of matrix metalloproteinase-2. FEBS Lett. 519, 147 (2002). https://doi.org/10.1016/S0014-5793(02)02742-4
- Oh, J., Seo, D. W., Diaz, T., Wei, B., Ward, Y., Ray, J. M., Morioka, Y., Shi, S., Kitayama, H., Takahashi, C., Noda, M. and Stetler-Stevenson, W. G. : Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK. Cancer Res. 64, 9062 (2004). https://doi.org/10.1158/0008-5472.CAN-04-1981
- Guedez, L., Rivera, A. M., Salloum, R., Miller, M. L., Diegmueller, J. J., Bungay, P. M. and Stetler-Stevenson, W. G. : Quantitative assessment of angiogenic responses by the directed in vivo angiogenesis assay. Am. J. Pathol. 162, 1431 (2003). https://doi.org/10.1016/S0002-9440(10)64276-9
- Seo, D. W., Li, H., Qu, C. K., Oh, J., Kim, Y. S., Diaz, T., Wei, B. Y., Han, J. W. and Stetler-Stevenson, W. G. : Shp-1 mediates the anti-proliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells. J. Biol. Chem. 281, 3711 (2006). https://doi.org/10.1074/jbc.M509932200
- Zhang, H. and Issekutz, A. C. : Down-modulation of monocyte transendothelial migration and endothelial adhesion molecule expression by fibroblast growth factor: reversal by the antiangiogenic agent SU6668. Am. J. Pathol. 160, 2219 (2002). https://doi.org/10.1016/S0002-9440(10)61169-8
- Murphy, A. N., Unsworth, E. J. and Stetler-Stevenson, W. G. : Tissue inhibitor of metalloproteinases-s inhibits bFGF-induced human microvascular endothelial cell proliferation. J. Cell. Physiol. 157, 351 (1993). https://doi.org/10.1002/jcp.1041570219
- Seo, D. W., Kim, S. H., Eom, S. H., Yoon, H. J., Cho, Y. R., Kim, P. H., Kim, Y. K., Han, J. W., Diaz, T., Wei, B. Y. and Stetler- Stevenson, W. G. : TIMP-2 disrupts FGF-2-induced downstream signaling pathways. Microvasc. Res. 76, 145 (2008). https://doi.org/10.1016/j.mvr.2008.07.003
- Chang, Z., Choon, A. and Friedl, A. : Endostatin binds to blood vessels in situ independent of heparan sulfate and does not compete for fibroblast growth factor-2 binding. Am. J. Pathol. 155, 71 (1999). https://doi.org/10.1016/S0002-9440(10)65101-2