Journal of Gastric Cancer

  • 제10권4호
  • /
  • Pages.206-211
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  • 2010
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  • 2093-582X(pISSN)
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  • 2093-5641(eISSN)
대한위암학회 (The Korean Gastric Cancer Association)
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The Feasibility of Short Term Prophylactic Antibiotics in Gastric Cancer Surgery

  • Lee, Jun-Suh (Division of Gastrointestinal Surgery, Department of Surgery, The Catholic University of Korea, School of Medicine) ;
  • Lee, Han-Hong (Division of Gastrointestinal Surgery, Department of Surgery, The Catholic University of Korea, School of Medicine) ;
  • Song, Kyo-Young (Division of Gastrointestinal Surgery, Department of Surgery, The Catholic University of Korea, School of Medicine) ;
  • Park, Cho-Hyun (Division of Gastrointestinal Surgery, Department of Surgery, The Catholic University of Korea, School of Medicine) ;
  • Jeon, Hae-Myung (Division of Gastrointestinal Surgery, Department of Surgery, The Catholic University of Korea, School of Medicine)
  • 투고 : 2010.08.31
  • 심사 : 2010.09.25
  • 발행 : 2010.12.30
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초록

Purpose: Most surgeons administer prophylactic antibiotics for 3 to 5 days postoperatively. However, the Center for Disease Control (CDC) guideline recommends antibiotic therapy for 24 hours or less in clean/uncontaminated surgery. Thus, we prospectively studied the use of short term prophylactic antibiotic therapy after gastric cancer surgery. Materials and Methods: A total of 103 patients who underwent gastric cancer surgery between October 2007 and June 2008 were prospectively enrolled in a short term prophylactic antibiotics program. One gram of cefoxitin was administered 30 minutes before the incision, and one additional gram was administered intraoperatively for cases with an operation time over 3 hours. Postoperatively, one gram was administered 3 times, every 8 hours. Patients were checked routinely for fever. All cases received open surgery, and the surgical wounds were dressed and checked for Surgical Site Infection (SSI) daily. Results: Of the 103 patients, 15 were dropped based on exclusion criteria (severe organ dysfunction, combined resection of the colon, etc). The remaining 88 patients were included in the short-term program of prophylactic antibiotic use. Of these patients, SSIs were detected in 8 (9.1%) and fever after 2 postoperative days was detected in 11 (12.5%). The incidence of SSIs increased with patient age, and postoperative fever correlated with operation time. Conclusions: Short term prophylactic antibiotic usage is feasible in patients who undergo gastric cancer surgery, and where there are no grave comorbidities or combined resection.

키워드

참고문헌

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피인용 문헌

  1. Overview of Antibiotic Use in Korea vol.44, pp.4, 2012, https://doi.org/10.3947/ic.2012.44.4.250
  2. Surgical Antimicrobial Prophylaxis and Incidence of Surgical Site Infections at Ethiopian Tertiary-Care Teaching Hospital vol.12, pp.None, 2019, https://doi.org/10.1177/1178633719892267