Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Psychosocial aspects of childhood cancer survivors

  • Seo, Jong-Jin (Department of Pediatrics, University of Ulsan College of Medicine)
  • Received : 2012.03.10
  • Accepted : 2010.03.22
  • Published : 2010.04.15
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Abstract

The majority of childhood cancer survivors and their families will be psychologically healthy, but may desire and benefit from preventive care. A significant portion of the survivor population will be psychosocially distressed in various aspects by their harsh experience of long cancer treatment, and may warrant professional intervention and treatment. Pediatricians should be aware of the late psychological effects that can occur a year or 2 after treatment, possibly in many aspects of a survivor's life. Not only the cancer diagnosis, but also treatments such as chemotherapy, irradiation, and surgical intervention may exert different long-term effects on the psychosocial outcomes of survivors. Pediatricians need to be more concerned with maintaining and improving the psychological health of this growing number of childhood cancer survivors through long-term follow-up clinics, community support, or self-help groups. Research on all of the psychosocial aspects of childhood cancer survivors is important to recognize the reality and problems they face in Korea.

Keywords

References

  1. Noll RB, Maclean WE, Whitt JK, Kaleita TA, Stehbens JA, WaskerwitzMJ, et al. Behavioral adjustment and social functioning of long-term survivors of childhood leukemia: Parent and teacher reports. J Pediatr Psychol 1977;22:827-41.
  2. Noll R, Bukowski W, Davies W, Koontz K, Kularkrni R. Adjustment in the peer system of children with cancer: A two-year follow-up study. J Pediatr Psychol 1993;18:351-64. https://doi.org/10.1093/jpepsy/18.3.351
  3. Newby WL, Brown RT, Pawletko TM, Gold SH, Whitt JK. Social skills and psychological adjustment of child and adolescent cancer survivors. Psychooncology 2000;19:113-26.
  4. Elkin TD, Phipps S, Mulhern RK, Fairclough D. Psychological functioning of adolescent and young adult survivorsof pediatric malignancy. Med Pediatr Oncol 1997; 29:582-8. https://doi.org/10.1002/(SICI)1096-911X(199712)29:6<582::AID-MPO13>3.0.CO;2-8
  5. Kupst MJ, Natta M, Richardson C, Schulman J, Lavigne J, Das L. Family coping with pediatric leukemia: Ten yearsafter treatment. J Pediatr Psychol 1995;20:601-17. https://doi.org/10.1093/jpepsy/20.5.601
  6. Sawyer M, Antoniou G, Toogood I, Rice M, Baghurst P. Childhood cancer: A 4-year prospective study of the psychological adjustment of children and parents. J Pediatr Hematol Oncol 2000;22:214-20. https://doi.org/10.1097/00043426-200005000-00006
  7. Ross L, Johansen C, Dalton S O, Mellemkjaer L, Thornassen LH, Mortensen PB, et al. Psychiatric hospitalizationsamong survivors of cancer in childhood or adolescence. N Engl J Med 2003;349:650-7. https://doi.org/10.1056/NEJMoa022672
  8. Glover DA, Byrne J, Mills JL, Robison LL, Nicholson HS, Meadows A, et al. Impact of CNS treatment on mood in adult survivors of childhood leukemia: A report from the Childrens Cancer Group. J Clin Oncol 2003;21:4395-401. https://doi.org/10.1200/JCO.2003.04.089
  9. Recklitis C, OLeary T, Diller L. Utility of routine psychological screening in the childhood cancer survivor clinic. J Clin Oncol 2003;21:787-92. https://doi.org/10.1200/JCO.2003.05.158
  10. Rourke M, Hobbie W, Kazak A. Posttraumatic stress in young adult survivors of childhood cancer. 7th international conference on long-term complications of treatment of children and adolescents for cancer, Niagara on the Lake, Ontario, Canada, 2002.
  11. Rourke M, Stuber M, Hobbie W, Kazak A. Posttraumatic stress disorder: understanding the psychosocial impact ofsurviving childhood cancer into young adulthood. J Pediatr Oncol Nurs 1999;16:126-35.
  12. Stuber M, KazakA, Meeske K, Barakat L. Is posttraumatic stress a viable model for understanding responses to childhood cancer? Psychiatr Clin North Am 1998;7:169-82.
  13. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th ed. Arlington. American Psychiatric Publishing, 2000
  14. Rourke M, Kazak A. Psychological aspects of long-term survivorship. In: Schwartz CL, Hobbie WL, Constine LS, Ruccione KS, editors. Survivors of childhood and adolescent cancer. 1st ed. Derlin: Springer, 2005:295-304.
  15. Brown R, Madan-Swain A, Lambert R. Posttraumatic stress symptoms in adolescent survivors of childhood cancer and their mothers. J Traum Stress 2003;309-18.
  16. Erickson S, Steiner H. Trauma and personality correlates in long term pediatric cancer survivors. Child Psychiatr Hum Dev 2001;31:195-213. https://doi.org/10.1023/A:1026477321319
  17. Kazak A, Barakat L, Alderfer M, Rourke M, Meeske K, Gallagher P, et al. Posttraumatic stress in survivors of childhood cancer and their mothers: development and validation of the Impact of Traumatic Stressors Interview Schedule (ITSS). J Clin Psychol Med Sett 2001;8:307-23. https://doi.org/10.1023/A:1011977031826
  18. Manne S, DuHamel K, Gallelli K, Sorgen K, Redd WH. Posttraumatic stress disorder among mothers of pediatric cancer survivors: Diagnosis, comorbidity, and utility of the PTSD checklists as a screening instrument. J Pediatr Psychol 1998;23:357-66. https://doi.org/10.1093/jpepsy/23.6.357
  19. Manne S, DuHamel K, Nereo N, Ostroff J, Parsons S, Martini R, et al. Predictors of PTSD in mothers of childrenundergoing bone marrow transplantation: The role of cognitive and social processes. J Pediatr Psychol 2002;27:607-17. https://doi.org/10.1093/jpepsy/27.7.607
  20. Eiser C, Vance YH, Glaser A, Galvin H. The value of the PedsQTLM in assessing quality of life in survivors of childhood cancer. Child Care Health Dev 2003;29:95-102. https://doi.org/10.1046/j.1365-2214.2003.00318.x
  21. Langeveld NE, Stam H, Grootenhuis MA, Last BF. Quality of life in young adult survivors of childhood cancer. Supp Care Cancer 2002;10:579-600. https://doi.org/10.1007/s00520-002-0388-6
  22. Haupt R, Fears TR, Robison LL, Mills JL, Nicholson S, ZeltzerLK, et al. Educational attainment in long-term survivors of childhood acute lymphoblastic leukemia. JAMA 1994;272: 1427-32. https://doi.org/10.1001/jama.272.18.1427
  23. Langeveld NE, UbbinkMC, Last BF, Grootenhuis MA, Voute PA, DeHaan RJ. Educational achievement, employment and living situation in long-term young adult survivors of childhood cancer in the Netherlands. Psychooncology 2003; 12:213-25. https://doi.org/10.1002/pon.628
  24. Nagarajan R, Neglia JP, Clohisy DR, Yasui Y, Greenberg M, Hudson M, et al. Education, employment, insurance, and marital status among 694 survivors of pediatric lower extremity bone tumors: a report of the Childhood Cancer Survivor Study. Cancer 2003;97:2554-64. https://doi.org/10.1002/cncr.11363
  25. Rauck AM, Green DM, Yasui Y, Mertens A, Robinson LL. Marriage in the survivors of childhood cancer: A preliminary description from the Childhood Cancer Survivor Study. Med Pediatr Oncol 1999;33:60-3 https://doi.org/10.1002/(SICI)1096-911X(199907)33:1<60::AID-MPO11>3.0.CO;2-H
  26. Vannatta K, Zeller M, Noll RB, Koontz K. Social functioning of children surviving bone marrow transplantation. J Pediatr Psychol 1998;23:169-78. https://doi.org/10.1093/jpepsy/23.3.169
  27. Mackie E, Hill J, Kondryn H, McNally R. Adult psychosocial outcomes in long-term survivors of acute lymphoblastic leukaemia and Wilms tumour: A controlled study. Lancet 2000;355:1310-14. https://doi.org/10.1016/S0140-6736(00)02112-7
  28. Zeltzer LK, Recklitis C, Buchbinder D, Zebrack B, Casillas J, Tsao JC, et al. Psychological status in childhood cancer survivors: A report from the Childhood Cancer Survivor Study. J Clin Oncol 2009;27:2936-404.
  29. Fuemmeler BF, Elkin TD, Mullins LL. Survivors of childhood brain tumors: Behavioral, emotional, and social adjustment. Clin Psychol Rev 2001;22:547-85.
  30. Holmquist LA, Scott J. Treatment, age, and time-related predictors of behavioral outcome in pediatric brain tumor survivors. J Clin Psychol Med Sett 2002;9:315-21. https://doi.org/10.1023/A:1020791018897
  31. Van Dongen-Melman JE, Pruyn JFA, DeGroot A, Koot HM, Halllen K, Verhulst FC. Late psychosocial consequences for parents of children who survived cancer. J Pediatr Psychol 1995;20:567-86. https://doi.org/10.1093/jpepsy/20.5.567
  32. Haupt R, Spinetta JJ, Ban I, Barr RD, Beck JD, Byrne J, et al. Long term survivors of childhood cancer: Cure and care. The Eric statement. Eur J Cancer 2007;43:1778-80. https://doi.org/10.1016/j.ejca.2007.04.015
  33. Hobbie W, Ogle S. Transitional care for young adult survivors of childhood cancer. Semin Oncol Nurs 2001;17: 268-73. https://doi.org/10.1053/sonu.2001.27922
  34. Oeffinger KC. Longitudinal risk-based health care for adult survivors of childhood cancer. Curr Prob Cancer 2003;27: 143-67. https://doi.org/10.1016/S0147-0272(03)00031-X
  35. Zeltzer LK, Lu Q, Leisenring W, Tsao JCI, Recklitis C, Amstrong G, et al. Psychosocial outcomes and health-related quality of life in adult childhood cancer survivors: A report from the childhood cancer survivor study. Cancer Epidemiol Biomarkers Prev 2008;17:435-46. https://doi.org/10.1158/1055-9965.EPI-07-2541
  36. Schultz KA, Ness KK, Whitton J, Recklitis C, Zebrack B, Robison LL, et al. Behavioral and social outcomes in adolescentsurvivors of childhood cancer survivors: a report from the Childhood Cancer Survivor Study. J Clin Oncol 2007;25:3649-56. https://doi.org/10.1200/JCO.2006.09.2486
  37. Ness KK, Gurney JG, Zeltzer LK, Reisenring W, Mulrooney DA, Nathan PC, et al. The impact of limitation in physical, executive, and emotional function in the health-related quality of life among adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Arch Phys Rehabil 2008;89:128-36. https://doi.org/10.1016/j.apmr.2007.08.123
  38. Nathan PC, Ness KK, Greenberg ML, Hudson M, Wolden S, Davidoff A, et al. Health-related quality of life in adult survivors of childhood Wilms tumor or neuroblastoma: A report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer 2007;49:704-15. https://doi.org/10.1002/pbc.20949
  39. Kadan-Lottick NS, Robison L, Gurney JG, Neglia JP, Yasui Y, Hayashi R, et al. Childhood cancer survivors knowledge about their past diagnosis and treatment: Childhood Cancer Survivor Study. JAMA 2002;287:1832-9. https://doi.org/10.1001/jama.287.14.1832
  40. Hobbie W, Stuber M, Meeske K, Wissler K, Rourke M, Ruccione K, et al. Symptoms of posttraumatic stress in young adult survivors of childhood cancer. J Clin Oncol 2000;18: 4060-6.
  41. Hudson MM, Mertens AC, Yasui Y, Hobbie W, Chen H, Gurney JG, et al. Health status of adult long-term survivorsof childhood cancer: A report from the Childhood C ancer Survivor Study. JAMA 2003;290:1583-92. https://doi.org/10.1001/jama.290.12.1583
  42. Van Dongen-Melman JE. Developing psychosocial aftercare for children surviving cancer and their families. Acta Oncol 2000;139:23-31.
  43. Eiser C, Hill JJ, Blacklay A. Surviving cancer: what does it mean for you? An evaluation of a clinic-based intervention for survivors of childhood cancer. Psychooncology 2000;9: 214-20. https://doi.org/10.1002/1099-1611(200005/06)9:3<214::AID-PON455>3.0.CO;2-O
  44. Park HJ, Nam BH, Yoon YH, Yang WJ, Kang HJ, Shin HY, et al. Establishment of Korean childhood cancer survivor cohort and long-term follow-up system. Clin Pediatr Hematol Oncol 2007;14:1-42.
  45. Kim YJ, Cha HG, Kim CA, Park YJ, Kim HJ, Seo JJ, et al. Childhood cancer survivors quality of life based on their parents support and past history. J Korean Acad Psychiatr Ment Health Nurs 2008;17:85-96.

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