Interpretation of Antimicrobial Susceptibility Test According to Resistance Mechanism of ${\beta}$-lactam in Enterobacteriacae

장내세균에서 ${\beta}$-lactam 항균제의 내성기전별 항균제 감수성검사의 해석

  • Lee, Chae-Hoon (Department of Laboratory Medicine, College of Medicine, Yeungnam University)
  • 이채훈 (영남대학교 의과대학 진단검사의학교실)
  • Published : 2010.06.30

Abstract

It is important to select appropriate antimicrobials for the treatment of infection according to the results of antimicrobial susceptibility tests (ASTs), yet the clinical isolates are sometimes susceptible to antibiotics that are clinically ineffective or this is due to technical error of the ASTs. So, interpretive reading of ASTs is needed and especially for the ${\beta}$-lactams for treating $Enterobacteriacae$. This review describes the interpretive reading of ASTs according to natural antimicrobial resistance and the mechanisms of mechanisms, with giving special attention to the antibiotics phenotypes for $Enterobacteriacae$. Further, as all the diffent tissues have a different antimicrobial concentration for identical antimicrobials, more information is needed on the antimicrobial tissue distribution for the appropriate treatment of infection. (ED note: I hope you send me the paper.)

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