The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Effect of Maca Supplementation on Scopolamine-Induced Memory Impairment of Mice

마카(Lepidium meyenii) 보충이 생쥐에서 Scopolamine으로 손상된 기억력 회복에 미치는 효과

  • 이홍미 (대진대학교 식품영양학과) ;
  • 박은진 (유진종합식품(주)) ;
  • 전인숙 (대진대학교 식품영양학과) ;
  • 강용수 (유진종합식품(주)) ;
  • 진동일 (충남대학교 동물자원생명과학과) ;
  • 정해정 (대진대학교 식품영양학과)
  • Received : 2010.09.16
  • Accepted : 2010.11.21
  • Published : 2010.12.01
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Abstract

With an increase in the number of people suffering from ageing-related diseases in our rapidly aging society, interests in natural products such as maca(Lepidium meyenii), which has properties of enhancing cognition and sexual performance, have increased. This study was conducted to assess the effects of 7 weeks of maca extract supplementation(0.5~2.0 g/kg BW) on scopolamine-induced amnesia in mice and on sperm count in male mice. All doses of maca supplementation significantly protected against scopolamine-induced amnesia as determined by a Morris water maze, but not according to passive avoidance tests. Maca supplementation did not affect acetylcholinesterase activity in the whole brain, nor the testicular sperm count of male mice. This study suggests that maca may have some neuroprotective properties in mice, which will be further examined by future studies.

Keywords

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