References
- Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, et al. : TWEAK/Fn14 interaction regulated RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Arthritis Res Ther 8 : R146, 2006 https://doi.org/10.1186/ar2038
- Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, et al. : TWEAK, a new scereted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem 272 : 32401-32410, 1997 https://doi.org/10.1074/jbc.272.51.32401
- Deyo RA : Back surgery-who needs it? N Engl J Med 356 : 2239-2243, 2007 https://doi.org/10.1056/NEJMp078052
- Farndale RW, Buttle DJ, Barrett AJ : Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 883 : 173-177, 1986 https://doi.org/10.1016/0304-4165(86)90306-5
- Gruber HE, Norton HJ, Ingram JA, Hanley EN Jr : The Sox9 transcription factor in the human disc : decreased immunolocalization with age and disc degeneration. Spine 30 : 625-630, 2005 https://doi.org/10.1097/01.brs.0000155420.01444.c6
- Haro H, Crawford HC, Fingleton B, MacDougall JR, Shinomiya K, Spengler DM, et al. : Matrix metalloproteinase-3- dependent generation of a macrophage chemoattractant in a model of herniated disc resorption. J Clin Invest 105 : 133-141, 2000 https://doi.org/10.1172/JCI7090
-
Kwawakami Y, Rodriguez-Leon J, Belmonte JC : The role of TGF-
$\beta$ s and Sox9 during limb chondrogenesis. Curr Opin Cell Bio 18 : 723-729, 2006 https://doi.org/10.1016/j.ceb.2006.10.007 -
Kuh SU, Zhu Y, Li J, Tsai KJ, Fei Q, Hutton WC, et al. : Can TGF-
$\beta$ 1 and rhBMP-2 act in synergy to transform bone marrow stem cells to discogenic-type cells? Acta Neurochir (Wien) 150 : 1073-1079; discussion 1079, 2008 https://doi.org/10.1007/s00701-008-0029-z - Le Maitre CL, Freemont AJ, Hoyland JA : A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration. Int J Exp Pathol 87 : 17-28, 2006 https://doi.org/10.1111/j.0959-9673.2006.00449.x
- Le Maitre CL, Hoyland JA, Freemont AJ : Degeneration of intervertebral discs : current understanding of cellular and molecular events, and implications for novel therapies. Expert Rev Mol Med 29 : 1-10, 2001
- Le Maitre CL, Hoyland JA, Freemont AJ : Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc : an in situ-zymographic and gene therapy study. Arthritis Res Ther 9 : R83, 2007 https://doi.org/10.1186/ar2282
- Le Maitre CL, Hoyland JA, Freemont AJ : The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration. Arthritis Res Ther 7 : R732- R745, 2005 https://doi.org/10.1186/ar1732
-
Lee YJ, Kong MH, Song KY, Lee KH, Heo SH : The relation between SOX 9, TGF
$\beta$ 1 and proteoglycan in human intervertebral disc cells. J Korean Neurosurg Soc 43 : 149-154, 2008 https://doi.org/10.3340/jkns.2008.43.3.149 - Li J, Yoon ST, Hutton WC : Effect of bone morphogenetic protein- 2(BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cells. J Spinal Disord Tech 17 : 423-428, 2004 https://doi.org/10.1097/01.bsd.0000112084.85112.5d
- Martin MD, Boxell M, Malone DG : Pathophysiology of lumbar disc degeneration : a review of the literature. Neurosurg Focus 13 : E1, 2002
- Okargly A, Balwit JM, Haak-Frendscho M : Transforming Growth Factor beta-1 (TGF-beta-1) : a biological paradox. Promega Notes 47 : 10, 1994
- Perper SJ, Browning B, Burkly LC, Weng S, Gao C, Giza K, et al. : TWEAK is a novel arthritogenic mediator. J Immunol 177 : 2610-2620, 2006
- Podichetty VK : The aging spine : the role of inflammatory mediators in intervertebral disc degeneration. Cell Mol Biol 53 : 4-18, 2007
- Risbud MV, Albert TJ, Guttapalli A, Vresilovic EJ, Hillibrand AS, Vaccaro Ar, et al. : Differentiation of Mesenchymal Stem Cells towards a nucleus pulposus-like phenotype in vitro : implications for cell based transplantation therapy. Spine 29 : 2627-2632, 2004 https://doi.org/10.1097/01.brs.0000146462.92171.7f
- Stevens AL, Wheeler CA, Tannenbaum SR, Grodzinsky AJ : Nitric oxide enhances aggrecan degradation by aggrecanase in response to TNF-alpha but not IL-1beta treatment at a post-transcriptional level in bovine cartilage explants. Osteoarthritis Cartilage 16 : 489-497, 2008 https://doi.org/10.1016/j.joca.2007.07.015
- Wako M, Haro H, Ando T, Hatsushika K, Ohba T, Iwabuchi S, et al. : Novel function of TWEAK in inducing intervertebral disc degeneration. J Orthop Res 25 : 1438-1446, 2007 https://doi.org/10.1002/jor.20445
Cited by
- Cell differentiation modeled via a coupled two-switch regulatory network vol.20, pp.4, 2010, https://doi.org/10.1063/1.3505000
- BMP7-Based Functionalized Self-Assembling Peptides for Nucleus Pulposus Tissue Engineering vol.7, pp.31, 2010, https://doi.org/10.1021/acsami.5b03605
- Downregulated microRNA‐330 suppresses left ventricular remodeling via the TGF‐β1/Smad3 signaling pathway by targeting SRY in mice with myocardial ischemia–reperfusion injury vol.234, pp.7, 2010, https://doi.org/10.1002/jcp.27800