Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Asymmetric Michael Addition of Ketones to Nitroolefins Catalyzed by a New Chiral Catalyst

  • Wang, Lian-Jun (College of Chemistry and Chemical Engineering, Hunan Institute of Engineering) ;
  • Hu, Feng-Feng (College of Chemistry and Chemical Engineering, Hunan Institute of Engineering)
  • Received : 2010.02.11
  • Accepted : 2010.03.13
  • Published : 2010.05.20
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Abstract

A new chiral catalyst was synthesized and found that it could catalyzed the asymmetric Michael reaction of ketones with nitroolefins smoothly at room temperature, giving the desired adducts in 71 - 92% yields with excellent diastereoselectivities and high enantioselectivities (up to 95% ee).

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References

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