Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Meningoencephalitis in Dachshund Dog with Canine Distemper Virus Infection: 1.5 T and 7.0 T MRI Findings

닥스훈트견의 바이러스성 뇌수막염에서 1.5T와 7T 자기공명영상을 이용한 진단 증례

  • Kang, Min-Hee (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Deseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Park, Hee-Myung (BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Deseases and Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • 강민희 (건국대학교 수의과대학 내과학교실) ;
  • 박희명 (건국대학교 수의과대학 내과학교실)
  • Accepted : 2009.12.08
  • Published : 2010.12.31
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Abstract

A 6-year-old, intact female Dachshund was presented with generalized seizure for 2 days. Based on the neurologic and physical examinations, intracranial diseases were suspected. 1.5T and 7.0T magnetic resonance imaging (MRI) of the brain were taken. The MRI results revealed diffuse hyperintense lesions in the area of the diencephalon to the medulla oblongata in the T2-weighted images. Canine distemper virus-induced meningoencephalitis was confirmed by the result of RT-PCR of the cerebrospinal fluid (CSF). The dog was euthanized 7 days after diagnosis due to poor prognosis and clinical deterioration. Postmortem histopathologic examination was consistent with the MRI findings. This is the first case report using 1.5T and 7.0T MRI to compare the virus-induced intracranial lesions in meningoencephalitis.

6년령의 암컷 닥스훈트견이 2일전 발생한 발작증상으로 내원하였다. 기본 신체검사, 실험실 검사 및 신경검사를 통해, 뇌 질환에 의한 발작이 의심되었다. 환자는 1.5T와 7T 자기공명영상을 통한 진단이 시도 되었다. T2 영상에서 간뇌 에서 연수 부위까지 광범위한 고신호성 뇌병변이 관찰되었다. 뇌척수액의 중합효소연쇠반응(RT-PCR)을 통하여, 개 디스템퍼 바이러스가 검출되었으며, 이를 근거로, 개 디스템퍼 바이러스에 의한 뇌수막염이 최종 진단 되었다. 지속적인 상태 악화에 의해, 환자는 진단 7일 뒤 보호자의 요청에 의해 안락사가 실시되었다. 사후 부검을 통한 조직검사에서 자기공명영상과 같은 부위의 뇌병변이 확인 되었다. 결론적으로 본 증례는 바이러스에의한 뇌병변의 1.5T와 7T 자기공명영상을 통한 첫 번째 진단 증례 보고 이다.

Keywords

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