The Effects of Snail Secretion Filtrate on the damaged skin barrier's recovery of the Atopic dermatitis

달팽이 점액이 아토피 피부염 환자의 피부장벽 회복에 미치는 영향

  • 오민지 (세명대학교 한의과대학 안이비인후피부과학교실) ;
  • 박성민 ((주)코씨드바이오팜 연구소장) ;
  • 김희택 (세명대학교 한의과대학 안이비인후피부과학교실)
  • Received : 2010.11.08
  • Accepted : 2010.12.09
  • Published : 2010.12.25

Abstract

Purposes : The object of present study is to detect the Effects of Snail Secretion Filtrate and Hyaluronic acid on the skin barrier's recovery of the Atopic dermatitis. Methods : A total of 20 patients who visited Semyung Hanny Oriental Medical Center from september 1st, 2009 to August 31th, 2010 were included in this study. In this study, they were treated with Snail Secretion Filtrate(experimental group) and Hyaluronic acid(control group). For 4 weeks gross examination, hematological examination and instrumentation through skin-ANBT equipment were made before and after the experiments to see how well the products for experimental group act against those for control group in recovering the damaged skin barriers by Atopic dermatitis. Results : 1. In the primary endpoint, SCORAD Index showed a statistically significant decline in both the control group and the experimental group. However, the experimental group showed greater statistical significance than the control group. 2. In the secondary endpoint index of skin hydration, both the control group and the experimental group did not show a statistically significant increase. However, the degree of skin hydration in the experimental group is greater than in the control group. 3. In global assessment of efficacy, it was higher in the experimental group than in the control group for both the subjects and the researchers. 4. To evaluate the safety of the products for the human body, hematological examination and hematological biochemical examination were conducted; both the control group and the experimental group showed no abnormal level. Therefore, the safety of the products, if used for so long a time, proved to be safe for the human body. 5. Product satisfaction was higher in the experimental group than in the control group. Conclusions : According to above experiments, Snail Secretion Filtrate was effective on the Atopic dermatitis.

Keywords

References

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