Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

The Clinico-Statisitical Analysis of Ameloblastoma of Mandible

하악골에 발생한 법랑아세포종의 임상통계학적 분석

  • Yu, Kyoung-Hwan (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Kim, Su-Gwan (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Moon, Seong-Yong (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Oh, Ji-Su (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Lee, Jeong-Hoon (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University) ;
  • Kim, Jin-Ha (Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University)
  • 유경환 (조선대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 김수관 (조선대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 문성용 (조선대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 오지수 (조선대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 이정훈 (조선대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 김진하 (조선대학교 치의학전문대학원 구강악안면외과학교실)
  • Received : 2010.07.16
  • Accepted : 2010.10.14
  • Published : 2010.11.30
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Abstract

Purpose: In this study, we evaluated the relation between surgical methods and reccurrence rate by investigating clinical, radiological aspects and histopathological patterns of 26 patients who were diagnosed with amelobalstoma. Patients and Methods: In this study, we retrospectively investigated 26 patients who were diagnosed with ameloblastoma and treated at the Department of Oral and Maxillofacial Surgery of Chosun University Dental Hospital from January 2000 to December 2008. Results: The patients comprised 12 males (46.1%) and 14 females (53.9%), and their ages ranged from 10 to 69 years (average, 37.3 years). All cases presented a mandibular location, and in particular, 13 cases (50%) demonstrated an occurrence in the mandibular body. Clinically, 8 cases (30.8%) presented no symptoms, and the most prevalent chief complaint was swelling in 13 cases (50%). Radiographically, a unilocular type appeared in 14 cases (53.8%), and a multilocular type was observed in 10 cases (38.5%). Histopathologically, there were 8 follicular types (30.8%) and 7 plexiform types (26.9%). Conservative treatment was performed in 5 cases (19.2%), and radical treatment was performed in 21 cases (80.8%). The follow-up period ranged from 1 to 10 years. The total recurrence rate was 15.4%, and the mean duration of recurrence was 6.7 years. Three of the 5 cases (60%) that received conservative treatment demonstrated a recurrence, as compared to 1 of the 21 cases (4.8%) that underwent radical treatment. Conclusion: The radical treatment was more effective than the conservative treatment for recurrence prevention. We should consider a continuous follow-up check after operation.

Keywords

References

  1. Small IA, Waldron CA : Ameloblastomas of the jaws. J Oral Surg Oral Med Oral Pathol 8 : 281, 1955. https://doi.org/10.1016/0030-4220(55)90350-9
  2. Dhiravarangkura P : Roentgenographic survery of ameloblastoma in Osaka university dental school. J Dent Assoc Thailand 19 : 163, 1969.
  3. Becelli R, Carboni A, Cerulli G : Mandibular ameloblastoma: Analsis of surgical treatment carried out in 60 patients between 1977 and 1998. J Craniofac Surg 13 : 395, 2002. https://doi.org/10.1097/00001665-200205000-00006
  4. Kramer I, Pindborg J, Shear M : Histological typing of odontogenic tumors. Berlin, Springer, 1992.
  5. Hoffman PJ, Rankow RM, Potter GD : The fate of the uncontrolled ameloblastoma. J Oral Surg Oral Med Oral Pathol 26 : 419, 1968. https://doi.org/10.1016/0030-4220(68)90319-8
  6. Gardner DG : A pathologist's approach to the treatment of ameloblastoma. J Oral Maxillofac Surg 42 : 161, 1984. https://doi.org/10.1016/S0278-2391(84)80026-9
  7. Reichart PA, Philipsen HP, Sonner S : Ameloblastoma: biological profile of 3677 cases. Eur J Cancer B Oral Oncol 31 : 86, 1995. https://doi.org/10.1016/0964-1955(94)00037-5
  8. Nakamura N, Higuchi Y, Mitsayasu T et al : Comparison of long-term results between differents approaches to ameloblastoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93 : 13, 2002. https://doi.org/10.1067/moe.2002.119517
  9. Julio CB, Sergio loshii, Luciana BR : Conservative treatment of unicystic ameloblastoma. Am J Orthod Dentofacial Orhop 137 : 396, 2010. https://doi.org/10.1016/j.ajodo.2007.10.062
  10. Tamme T, Soots M, Kulla A et al : Odontogenic tumours, a collaborative retrospective study of 75 cases covering more then 25 years from Estonia. J Craniomaxillofac Surg 32 : 161, 2004. https://doi.org/10.1016/j.jcms.2003.12.004
  11. Paikkatt VJ, Sreedharan S, Kannan VP : Unicystic ameloblastoma of the maxilla: a case report. J Indian Soc Pedod Prev Dent 25 : 106, 2007. https://doi.org/10.4103/0970-4388.33459
  12. Barnes L, Eveson JW, Reichart P eds. World Health Organization Classification of Tumours, Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press, 2005.
  13. Muller H, Slootweg PJ : The ameloblastoma, the controversial approach to therapy. J Maxillofac Surg 13 : 79, 1985. https://doi.org/10.1016/S0301-0503(85)80021-7
  14. Takahashi K, Miyauchi K, Sato K : Treatment of ameloblastoma in children. Br J Oral Maxillofac Surg 36 : 453, 1998. https://doi.org/10.1016/S0266-4356(98)90462-4
  15. Nakamura N, Higuchi Y, Tashiro H et al : Marsupialization of cystic ameloblastoma: A clinical and histopathologic study of the growth characteristics before and after marsupialization. J Maxillofac Surg 53 : 748, 1995. https://doi.org/10.1016/0278-2391(95)90323-2
  16. Shigeru U, Mushimoto K, Shirasu R : Prognostic evaluation of ameloblastoma based on histologic and radiographic typing. J Maxillofac Surg 47 : 11, 1989.
  17. Olaitan AA, Adeola DS, Adekeye EO : Ameloblastoma: Clinical features and management of 315 cases from Kaduna, Nigeria. J Craniomaxillofac Surg 21 : 351, 1993. https://doi.org/10.1016/S1010-5182(05)80497-4
  18. Gardner DG, Pecak AMJ : The treatment of ameloblastoma based on pathologic and anatomic principles. Cancer 46 : 2514, 1980. https://doi.org/10.1002/1097-0142(19801201)46:11<2514::AID-CNCR2820461133>3.0.CO;2-9
  19. Molla MR, Shaheed I, Shrestha P : Ameloblastoma a clinical study of 13 cases. Bangladesh Med Res Counc Bull 17 : 29, 1991.
  20. Williams TP : Management of ameloblastoma: a changing perspective. J Oral Maxillofac Surg 51 : 1064, 1993. https://doi.org/10.1016/S0278-2391(10)80440-9
  21. Leider AS, Eversole LR, Barkin ME : Cystic ameloblastoma: a clinicopathologic analysis. Oral Surg Oral Med Oral Pathol 60 : 624, 1985. https://doi.org/10.1016/0030-4220(85)90366-4
  22. Phillipsen HP, Reichart PA : Unicystic ameloblastoma: a review of 193 cases from the literature. Oral Oncol Eur J Cancer 34 : 316, 1998.
  23. Chappelle KA, Stoelinga P, DeWilde P et al : Rational approach to diagnosis and treatment of ameloblastomas and odontogenic keratocysts. Br J Oral Maxillofac Surg 42 : 381, 2004.
  24. Ueno S, Mushimoto K, Shirasu R : A clinicopathological study of ameloblastoma. J Oral Maxillofac Surg 44 : 361, 1986. https://doi.org/10.1016/S0278-2391(86)80031-3
  25. Sirichitra V, Dhiravarangkura P : Intrabony ameloblastoma of the based on pathologic and anatomic principles. Cancer 46 : 2514, 1980. https://doi.org/10.1002/1097-0142(19801201)46:11<2514::AID-CNCR2820461133>3.0.CO;2-9
  26. Strytherz P, Shear M : Root resorption by ameloblastomas and cysts of jaws. Int J Oral Surgery 5 : 128, 1976. https://doi.org/10.1016/S0300-9785(76)80061-0
  27. Kim HS, Ryu JY, Yu MG et al : Clinical study of ameloblastoma on the jaw. J Kor Oral Maxillofac Surg 33 : 535, 2007.
  28. Vilembwa LA, Elizabeth AO, Kevin AW : Clinicopathologic features of ameloblastoma in Kenya: A 100year audit. J Craniomaxillofac Surg 19 : 1589, 2008.
  29. Reaume C : Ameloblastoma of the maxillary sinu. J Oral surgery 38 : 520, 1980.
  30. Adekeye EO : Ameloblastoma of the jaws: A survey of 109 Nigerian patients. J Oral Surgery 38 : 36, 1980.
  31. Shafer WG, Hine MK, Levy BM : A textbook of oral pathology 3rd ed, WB Saunders Company, 1985, p.251.
  32. Melhisch DR, Dahlin DC, Masson JK : Ameloblastoma: a clinicopathologic report. J Oral Surg 30 : 9, 1972.
  33. Sung IY, Ryu SH, Shin SH et al : Aclinicopathologic study on ameloblastoma. J Korean Asso Maxillofac Plast Reconstr Surg 25 : 41, 2003.
  34. Huffman GG, Thatcher JW : Ameloblastoma-The conservative surgical approach to treatment: report of four cases. J Oral Surg 32 : 850, 1974.
  35. Isacsson G, Andersson L, Forsslund H et al : Diagnosis and treatment of unicystic ameloblastoma. Int J Oral Maxillofac Surg 15 : 759, 1986. https://doi.org/10.1016/S0300-9785(86)80119-3
  36. Gardner DC, Corio RL : Plexiform unicystic ameloblastoma: A variant of ameloblastoma with a low recurrence rate after enucleation. Cancer 53 : 1730, 1983.
  37. Kil YK, Kim JCh, Hong YJ et al : J Korean Asso Maxillofac Plast Reconstr Surg 29 : 187, 2007.
  38. Kim HK, Lee EW : Effect on the enucleation of the intraosseous ameloblastoma. J Kor Oral Maxillofac Surg 29 : 140, 2003.
  39. Shatkin S, Hoffmeister FS : Ameloblastoma: a rational approach to therapy. Oral Sur Oral med Oral Pathol 12 : 79, 1965.
  40. Sampson DE, Pogrel MA : Management of mandibular ameloblastoma: the clinical basis for a treatment algorithm. J Oral Maxillofac Surg 57 : 1074, 1999. https://doi.org/10.1016/S0278-2391(99)90328-2
  41. Kim ChS, Oh MCh : The clinico - statistical analysis of the treatment of the ameloblastoma. J Korean Asso Maxillofac Plast Reconstr Surg 15 : 253, 1994.
  42. Gold L : Biologic behavior of ameloblastoma. Oral Maxillofac Surg Clin North Am 3 : 21, 1991.
  43. MacIntosh RB : Aggressive management of ameloblastoma. Oral Maxillofac Surg Clin North Am 3 : 73, 1991.
  44. Carlson ER : Ameloblastoma. Symposium on Odontogenic Tumors, AAOMS 82nd Annual Meeting and Scientific Sessions, San Francisco, CA, September 23, 2000.
  45. Eric RC, Robert EM : The ameloblastoma: primary, curative surgical managemnt. J Oral Maxilofac Surg 64 : 484, 2006. https://doi.org/10.1016/j.joms.2005.11.032
  46. Kunze E, Donath K, Luhr HG : Biology of metastasizing ameloblastoma. Pathol Res Pract 180 : 526, 1985. https://doi.org/10.1016/S0344-0338(85)80017-0
  47. Sammartino G, Zarrelli C, Urciuolo V et al : Effectiveness of a new decisional algorithm in managing mandibular ameloblastomas: a 10-years experience. Br J Oral Maxillofac Surg 45 : 306, 2007. https://doi.org/10.1016/j.bjoms.2006.08.023
  48. Yeo HH, Kim YK, Cho SI et al : Malignant ameloblastioma : a case report. J Korean Asso Maxillofac Plast Reconstr Surg 16 : 303, 1994.