Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Radical Additions of Arenethiols to Ynamides for the Selective Synthesis of N-[(Z)-2-(Arylsulfanyl)-1-alkenyl]amides

  • Sato, Akinori (Department of Material Chemistry, Graduate School of Engineering, Kyoto University) ;
  • Yorimitsu, Hideki (Department of Material Chemistry, Graduate School of Engineering, Kyoto University) ;
  • Oshima, Koichiro (Department of Material Chemistry, Graduate School of Engineering, Kyoto University)
  • Published : 2010.03.20
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Abstract

A variety of ynamides undergo highly regio- and stereoselective radical addition of arenethiols with the aid of triethylborane as a radical initiator. The products, N-[(Z)-2-arylsulfanyl-1-alkenyl]amides, can be reduced with triethylsilane in trifluoroacetic acid to yield N-[2-(arylsulfanyl)alkyl]amides.

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References

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