Asian-Australasian Journal of Animal Sciences

  • 제23권6호
  • /
  • Pages.733-741
  • /
  • 2010
  • /
  • 1011-2367(pISSN)
  • /
  • 1976-5517(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
권호 표지
DOI QR코드

DOI QR Code

Hypocholesterolemic Response to Karaya Saponin and Rhodobacter capsulatus in Broiler Chickens

  • Afrose, Sadia (Laboratory of Animal Biotechnology, Faculty of Agriculture, Shinshu University) ;
  • Hossain, Md. Sharoare (Laboratory of Animal Biotechnology, Faculty of Agriculture, Shinshu University) ;
  • Maki, Takaaki (Matsumoto Institute of Microorganisms Co., Ltd.) ;
  • Tsujii, Hirotada (Laboratory of Animal Biotechnology, Faculty of Agriculture, Shinshu University)
  • 투고 : 2009.09.13
  • 심사 : 2009.11.10
  • 발행 : 2010.06.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Dietary karaya saponin and Rhodobacter capsulatus (R. capsulatus) are known to have hypocholesterolemic actions, as reported in our previous studies. This study examined possible synergistic hypocholesterolemic effects of karaya saponin and R. capsulatus in broilers. A total of 150 broilers were allocated into 10 treatments: control, saponin 25 mg, saponin 50 mg, saponin 75 mg, saponin 25 mg+R. capsulatus 0.2 g, saponin 25 mg+R. capsulatus 0.4 g, saponin 50 mg+R. capsulatus 0.2 g, saponin 50 mg+R. capsulatus 0.4 g, saponin 75 mg+R. capsulatus 0.2 g and saponin 75 mg+R. capsulatus 0.4 g. Feed intake and feed efficiency were improved when karaya saponin and R. capsulatus were synergistically supplemented in the diet. Combinations of karaya saponin, especially supplementation of karaya saponin 50 mg+R. capsulatus 0.4 g were shown to have potential hypolipidemic actions in breast and thigh muscle cholesterol and triglycerides, serum cholesterol, low density lipoprotein-cholesterol and triglycerides, as well as improved high density lipoprotein (HDL)-cholesterol (p<0.05). Compared to the control, almost all the treatments significantly increased serum, liver and fecal concentrations of bile acids (p<0.05). Supplementation of both karaya saponin (75 mg) and saponin 50 mg+R. capsulatus 0.4 g reduced palmitic acid (C16:0) and stearic acid (C18:0) in a similar fashion (p<0.05). The ratios of PUFA:SFA or PUFA+MUFA:SFA in the thigh and breast muscle of broilers were greater in karaya saponin and R. capsulatus supplemented groups than in the control group. Thus, our study concluded that supplementation of karaya saponin synergistically with R. capsulatus in the diet of broilers is an effective way to obtain low-cholesterol, low-triglyceride and high HDL-cholesterol enriched poultry meat with a unique fatty acid balance.

키워드

참고문헌

  1. 2007Afrose, S., M. S. Hossain, T. Maki and H. Tsujii. 2009a. Karaya root saponin exerts a hypocholesterolemic response in rats fed a high-cholesterol diet. Nutr. Res. 29:350-354 https://doi.org/10.1016/j.nutres.2009.05.008
  2. Afrose, S., M. S. Hossain and H. Tsujii. 2009b. Effect of dietary karaya saponin on serum and egg yolk cholesterol in laying hens. Br. Poult. Sci. (submitted) https://doi.org/10.1080/00071668.2010.526924
  3. Afrose, S., M. S. Hossain, T. Maki and H. Tsujii. 2009c. Effects of karaya saponin and Rhodobacter capsulatus on yolk cholesterol in laying hens. Br. Poult. Sci. (accepted) https://doi.org/10.1080/00071668.2010.495469
  4. American Health Association. 1988. Report of the expert panel on population strategies for blood cholesterol reduction. National Cholesterol Education Program; Natlional Heart, Lung, Blood Institute; National Institute of Health (Dallas, TX)
  5. Behall, K. M., K. H. Lee and P. B. Moster. 1984. Blood lipids and lipoproteins in adult men fed four refined fibers. Am. J. Clin. Nutr. 39:209-214
  6. Brenner, R. R. 1989. Factors influencing fatty acid chain elongation and desaturation. In: The role of fats in human nutrition (Ed. A. J. Ergroesen and M. Crawfold). pp. 45-79. Academic Press. New York
  7. Chan, J. K., V. M. Bruce and B. E. McDonald. 1991. Dietary α-linoleic acid is as effective as oleic acid and linoleic acid in lowering blood cholesterol in normolipidemic men. Am. J. Clin. Nutr. 53:1230-1234
  8. Chobanian, A. V. and W. Hollande. 1962. Body cholesterol metabolism in man. I. The equilibration of serum and tissue cholesterol. J. Clin. Invest. 41:1732 https://doi.org/10.1172/JCI104631
  9. Gee, J. M. and I. T. Johnson. 1988. Interactions between hemolytic saponins, bile salts and small intestinal mucosa in the rat. J. Nutr. 118:1391-1397
  10. Hegsted, D. M., R. B. McGandy, M. L. Myers and F. J. Stare. 1965. Quantitative effects of dietary fat on serum cholesterol in man. Am. J. Clin. Nutr. 17:281-295
  11. Hornstra, G., C. A. Barth, C. Galli, R. P. Mensink, M. Mountanen, R. A. Riermesma, M. Roberfroid, V. G. Salminen and P. M. Verschuren. 1998. Functional food science and the cardiovascular system. Br. J. Nutr. 80:113-146 https://doi.org/10.1079/BJN19980107
  12. Hossain, S. M. and R. Blair. 2007. Chitin utilisation by broilers and its effect on body composition and blood metabolites. Br. Poult. Sci. 48:33-38 https://doi.org/10.1080/00071660601156529
  13. Kern, F. J. 1991. Normal plasma cholesterol in an 88 year old man who eats 25 eggs a day: mechanisms of adaptation. N. Engl. J. Med. 324:896-899 https://doi.org/10.1056/NEJM199103283241306
  14. Keys, A., J. T. Anderson and F. Grande. 1957. Prediction of serumcholesterol responses of man to changes in fats in the diet. Lancet 2:959-966
  15. Konjufca, V. H., G. M. Pesti and R. I. Bakalli. 1997. Modulation of cholesterol levels in broilers meat by dietary garlic and copper. Poult. Sci. 76:1264-1271
  16. Kubena, L. F., J. W. Deaton, T. C. Chen and F. N. Reece. 1974. Factors influence the quantity of abdominal fat in broiler. I. Rearing temperature, sex, age or weight and dietary choline chlorine and inositol supplementation. Poult. Sci. 53:211-214 https://doi.org/10.3382/ps.0530211
  17. Li, H., Q. J. Wang, D. N. Zhu and Y. Yang. 2007. Reinioside C, a triterpene saponin of Polygala aureocauda Dunn exerts hypolipidemic effect on hyperlipidemic mice. Phytother. Res. 22:159-164 https://doi.org/10.1002/ptr.2262
  18. Matsuura, M. 2001. Saponins in garlic as modifiers of the risk of cardiovascular disease. J. Nutr. 131:1000-1005
  19. Mattson, F. H. and S. M. Guardy. 1985. Comparison of effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. J. Lipid Res. 26:194-202
  20. McDonald, B. E., J. M. Gerard, V. M. Bruce and E. J. Corner. 1989. Comparison of the effect of canola oil and sunflower oil on plasma lipids and lipoproteins and on in vivo thromboxane A2 and prostacyclin production in healthy young man. Am. J. Clin. Nutr. 50:1382-1388
  21. Milgate, J. and D. C. K. Roberts. 1995. The nutritional and biological significance of saponins. Nutr. Res. 15:1223-1249 https://doi.org/10.1016/0271-5317(95)00081-S
  22. Potter, S. M., R. Jimenez-Flores, J. Pollack, T. A. Lone and M. D. Berber-Jimenez. 1993. Protein saponin interaction and its influence on blood lipids. J. Agric. Food Chem. 41:1287-1291 https://doi.org/10.1021/jf00032a023
  23. Russell, D. W. 2003. The enzymes, regulation and genetics of bile acid synthesis. Annu. Rev. Biochem. 72:137-174 https://doi.org/10.1146/annurev.biochem.72.121801.161712
  24. Salma, U., A. G. Miah, K. M. A. Tateq, T. Maki and H. Tsujii. 2007a. Effect of dietary Rhodobacter capsulatus on egg-yolk cholesterol and laying hen performance. Poult. Sci. 86:714-719
  25. Salma, U., A. G. Miah, T. Maki, M. Nishimura and H. Tsujii. 2007b. Effect of dietary Rhodobacter capsulatus on cholesterol concentration and fatty acids composition in broiler meat. Poult. Sci. 86:1920-1926
  26. Salma, U., A. G. Miah, T. Maki and H. Tsujii. 2008. Effect of dietary Rhodobacter capsulatus on cholesterol concentration and fatty acid composition in Japanese quail (Coturnix japonica) egg. J. Poult. Sci. 44:375-382 https://doi.org/10.2141/jpsa.44.375
  27. SAS Institute. 2000. SAS User’s Guide: Statistics. Version 8 ed. SAS Institute Inc. Cary NC
  28. Sidhu, G. S. and D. G. Oakenfull. 1986. A mechanism for the hypocholesterolaemic activity of saponins. Br. J. Nutr. 55:643-649 https://doi.org/10.1079/BJN19860070
  29. Son, I. S., J. H. Kim, H. Y. Sohn, K. H. Son, J. S. Kim and C. S. Kwon. 2007. Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of Yam (Dioscorea spp.), on high cholesterol fed rats. Biosci. Biotechnol. Biochem. 71:3063-3071 https://doi.org/10.1271/bbb.70472
  30. Southon, S., I. T. Johnson, J. M. Gee and K. R. Prince. 1988. The effect of Gypsophylla saponins in the diet on mineral status and plasma cholesterol concentration in the rat. Br. J. Nutr. 59:49-55 https://doi.org/10.1079/BJN19880008
  31. Tsujii, H., M. Nishioka, U. Salma, A. G. Miah, T. Maki and M. G. Lee. 2007. Comparative study on hypocholesterolemic effect of Rhodopseudomonas palustris and Rhodobacter capsulatus on rats fed a high-cholesterol diet. Anim. Sci. J. 78:535-540 https://doi.org/10.1111/j.1740-0929.2007.00473.x
  32. Tsujii, H., Y. Kuwabara, U. Salma, A. G. Miah, M. Nishimura and T. Maki. 2008. Effect of dietary Rhodobacter capsulatus on cholesterol, triglyceride concentration, and meat quality of finishing pig. Anim. Sci. J. 79:460-465 https://doi.org/10.1111/j.1740-0929.2008.00550.x
  33. Zhang, Y. G., H. G. Zhang, G. Y. Zhang, J. S. Fan, X. H. Li, Y. H. Liu, S. H. Li, X. M. Lian and Z. Tang. 2008. Panax notoginseng saponins attenuate atherosclerosis in rats by regulating the blood lipid profile and anti-inflammatory action. Clin. Exp. Pharmacol. Physiol. 35:1238-1244 https://doi.org/10.1111/j.1440-1681.2008.04997.x
  34. Zhao, H. L., S. V. Harding, C. P. Marinangeli, Y. S. Kim and P. J. Jones. 2008. Hypocholesterolemic and anti-obesity effects of saponins from Platycodon grandiflorum in hamsters fed atherogenic diets. J. Food Sci. 73:195-200 https://doi.org/10.1111/j.1750-3841.2008.00915.x
  35. Zhou, T. X., Y. J. Chen, J. S. Yoo, Y. Huang, J. H. Lee, H. D. Jang, S. O. Shin, H. J. Kim, J. H. Cho and I. H. Kim. 2009. Effects of chitooligosaccharide supplementation on performance, blood characteristics, relative organ weight, and meat quality in broiler chickens. Poult. Sci. 88:593-600 https://doi.org/10.3382/ps.2008-00285

피인용 문헌

  1. The Effect of Medicinal Herb Inclusion on Hematologic Status and Blood Lipid Profiles in Broiler Chickens vol.16, pp.10, 2017, https://doi.org/10.3923/ijps.2017.415.423
  2. The Effect of Fermented Sauropus androgynus Plus Bay Leaf Inclusion on the Hematologic and Lipid Profiles of Female Broiler Chickens vol.17, pp.9, 2018, https://doi.org/10.3923/ijps.2018.410.417
  3. Dietary supplementation of saponins to improve the quality and oxidative stability of broiler chicken meat vol.56, pp.4, 2010, https://doi.org/10.1007/s13197-019-03683-z
  4. Effect of dietary saponin rich soapnut (Sapindus mukorossi) shell powder on growth performance, immunity, serum biochemistry and gut health of broiler chickens vol.103, pp.6, 2010, https://doi.org/10.1111/jpn.13190
  5. Ipomea batatas Leaf Powder from Cameroon: Antioxidant Activity and Antihyperlipidemic Effect in Rats Fed with a High-Fat Diet vol.2021, pp.None, 2010, https://doi.org/10.1155/2021/5539878