Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Structure elucidation of a newly isolated saponin from Clerodendrum serratum (L) Moon

  • Bhujbal, Santosh S. (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research) ;
  • K.Nanda, Rabindra (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research) ;
  • S.Deoda, Ramesh (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research) ;
  • Kumar, Dinesh (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research) ;
  • Kewatkar, Shailesh M. (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research) ;
  • S.More, Laxmikant (Dept. of Pharmacognosy, Pad. D. Y. Patil Institute of Pharmaceutical Sciences and Research) ;
  • J.Patil, Manohar (Marathawada Mitra Mandal's, College of Pharmacy)
  • Received : 2010.03.31
  • Accepted : 2010.12.01
  • Published : 2010.12.31
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Abstract

Plant saponins are widely distributed amongst plants and have a wide range of biological properties. Icosahydropicenic acid, $C_{51}H_{80}O_{19}$ ((4S,6bS)-8a-((4,5-dihydroxy-6-methyl-3-((3R)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)carbonyl)-2-hydroxy-4, 6a, 6b, 11, 14b-pentamethyl-11-(2-methylprop-1-enyl)-3-(3,4,5-trihydroxy-6-(hydroxymethyl) - tetrahydro-2Hpyran-2-yloxy)-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicene-4-carboxylic acid), a new saponin was first time isolated from the roots of Clerodendrum Serratum (L) Moon (Verbenaceae). The structure elucidation of the compound was carried out by $^1H$ NMR and DART-MS studies.

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References

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