Neonatal Medicine

The Korean Society of Neonatology (대한신생아학회)
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Symptomatic Hepatitis A Virus Infection in a Newborn

증상을 동반한 신생아 A형 간염

  • Jin, Jang-Yong (Department of Pediatrics, Soonchunhyang University Hospital) ;
  • Hong, Ye-Seul (Department of Pediatrics, Soonchunhyang University Hospital) ;
  • Lee, Woo-Ryoung (Department of Pediatrics, Soonchunhyang University Hospital)
  • 진장용 (순천향대학교 의과대학 소아과학교실) ;
  • 홍예슬 (순천향대학교 의과대학 소아과학교실) ;
  • 이우령 (순천향대학교 의과대학 소아과학교실)
  • Published : 2010.05.31
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Abstract

Hepatitis A virus (HAV) infection is a common cause of acute hepatitis, but is rarely responsible for neonatal hepatitis. HAV infection is usually transmitted by the fecal-oral route, but during the neonatal period can be transmitted by the intrauterine vertical route or postnatal horizontal route. HAV infection is usually self-limited, but it can be potentially life-threatening in adults. The clinical course and symptoms are mild and the infection can be asymptomatic in newborns. Recently, we experienced a case of symptomatic neonatal hepatitis A. To our knowledge, this is the first case of neonatal hepatitis with HAV infection in Korea.

성인에서 A형 간염은 현증 감염이 대부분이지만, 소아에서는 무증상 또는 경한 증상을 보이는 경우가 많았다. 그동안 외국에서는 임신 및 분만 기간 동안에 발생한 A형 간염의 산모와 이로 인한 신생아 A형 간염에 대한 증례 보고가 드물지 않게 있었다. 국내에서는 20대와 30대의 젊은 성인에서 A형 간염에 대한 항체 양성률이 낮아지고 있는 가운데, 이들 산모들의 A형 간염에 대한 위험성이 증가하고 있는 상황이며, 아직까지 국내에서는 A형 간염에 이환된 신생아에 대한 증례 보고가 없었다. 이에 저자들은 A형 간염 산모로부터 이환된 것으로 보이는 급성 A형 간염 신생아를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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