Dementia and Neurocognitive Disorders (대한치매학회지)

Korean Dementia Association (대한치매학회)
권호 표지

Recurrent Stroke-Like Episodes in a Patient with Elderly Onset Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS)

  • Song, Pamela (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Roh, Jee-Hoon (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Noh, Hyun-Jin (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Seo, Sang-Won (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Kwang-Ki (Department of Neurology, Dongguk University International Hospital, Dongguk University College of Medicine) ;
  • Na, Duk-L. (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Published : 2010.06.30
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Abstract

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) uncommonly develops after the age of 40. We describe a patient with MELAS whose first strokelike episode presented at age 65, followed by two more episodes. The brain MR imaging for each stroke-like episode demonstrated hyperintense lesion in diffusion weighted image (DWI), and variable signal intensities in apparent diffusion coefficient (ADC) maps in temporo-parietal and occipital regions. We diagnosed the patient as MELAS with 3243A>G point mutation.

Keywords

References

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