대한치매학회지 (Dementia and Neurocognitive Disorders)

대한치매학회 (Korean Dementia Association)
권호 표지

진행성 인지장애를 첫 증상으로 보인 치아적핵창백핵루이체위축증 1예

Dentatorubropallidoluysian Atrophy Presenting Progressive Cognitive Dysfunction as an Initial Symptom

  • 박종규 (순천향대학교 부천병원 신경과학교실) ;
  • 고지애 (순천향대학교 부천병원 신경과학교실) ;
  • 박정호 (순천향대학교 부천병원 신경과학교실) ;
  • 이태경 (순천향대학교 부천병원 신경과학교실) ;
  • 성기범 (순천향대학교 부천병원 신경과학교실) ;
  • 박선아 (순천향대학교 부천병원 신경과학교실)
  • Park, Jong-Kyu (Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital) ;
  • Ko, Ji-Ae (Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital) ;
  • Park, Jeong-Ho (Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital) ;
  • Lee, Tae-Kyeong (Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital) ;
  • Sung, Ki-Bum (Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital) ;
  • Park, Sun-Ah (Department of Neurology, College of Medicine, Soonchunhyang University Bucheon Hospital)
  • 발행 : 2010.06.30
⟨ 이전 논문 다음 논문 ⟩

초록

A 50-yr-old woman presented with progressive cognitive impairment and later developed abnormal movements. Brain magnetic resonance imaging (MRI) showed diffuse atrophy of the cerebellum and brainstem and severe high signal intensities in the periventricular white matter on T2-weighted images. The genetic analysis confirmed the diagnosis of dentatorubropallidoluysian atrophy (DRPLA). DRPLA should be considered in a patient with family history who showed cognitive impairment alone for a substantial period and severe white matter involvement with diffuse atrophy on MRI.

키워드

참고문헌

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