A Case of Temporal Lobe Epilepsy Presenting Wernicke' Aphasia

베르니케 실어증을 보인 측두엽 간질 1예

  • Kang, Kyung-Wook (Department of Neurology, Chonnam National University Medical School) ;
  • Kim, Byeong-C. (Department of Neurology, Chonnam National University Medical School) ;
  • Choi, Kang-Ho (Department of Neurology, Chonnam National University Medical School) ;
  • Song, Ho-Chun (Department of Nuclear Medicine, Chonnam National University Medical School) ;
  • Min, Jung-Joon (Department of Neurology, Chonnam National University Medical School) ;
  • Choi, Seong-Min (Department of Neurology, Chonnam National University Medical School) ;
  • Kang, Seung-Ho (Department of Neurology, Chonnam National University Medical School) ;
  • Lee, Seung-Han (Department of Neurology, Chonnam National University Medical School) ;
  • Park, Man-Seok (Department of Neurology, Chonnam National University Medical School) ;
  • Kim, Myeong-Kyu (Department of Neurology, Chonnam National University Medical School) ;
  • Cho, Ki-Hyun (Department of Neurology, Chonnam National University Medical School)
  • 강경욱 (전남대학교 의과대학 신경과학교실) ;
  • 김병채 (전남대학교 의과대학 신경과학교실) ;
  • 최강호 (전남대학교 의과대학 신경과학교실) ;
  • 송호천 (전남대학교 의과대학 핵의학교실) ;
  • 민정준 (전남대학교 의과대학 핵의학교실) ;
  • 최성민 (전남대학교 의과대학 신경과학교실) ;
  • 강승호 (전남대학교 의과대학 신경과학교실) ;
  • 이승한 (전남대학교 의과대학 신경과학교실) ;
  • 박만석 (전남대학교 의과대학 신경과학교실) ;
  • 김명규 (전남대학교 의과대학 신경과학교실) ;
  • 조기현 (전남대학교 의과대학 신경과학교실)
  • Published : 2010.06.30

Abstract

Wernicke' aphasia is a language disorder that impacts the comprehension of written and spoken language. A 48-yr-old woman had developed a transient sensory aphasia without focal neurological deficit. Brain MRI showed no structural lesion, but $^{18}F$-Fluorodeoxyglucose (FDG) positron emission tomography (PET) demonstrated glucose hypermetabolic activity in the left medial and superior temporal gyri, and middle frontal gyrus. Electroencephalogram (EEG) revealed spike discharges from the same area. We report a case of Wernicke' aphasia as an ictal phenomenon of temporal lobe epilepsy.

Keywords

References

  1. Ghosh D, Mohanty G, Prabhakar S. Ictal deafness-a report of three cases. Seizure 2001; 10: 130-3. https://doi.org/10.1016/S1059-1311(00)90476-X
  2. Knight RT, Cooper J. Status epilepticus manifesting as reversible Wernicke's aphasia. Epilepsia 1986; 27: 301-4. https://doi.org/10.1111/j.1528-1157.1986.tb03543.x
  3. Abou-Khalil B, Fakhoury T, Jennings M, Moots P, Warner J, Kessler RM. Inhibitory motor seizure: correlation with centroparietal structural and functional abnormalities. Acta Neurol Scand 1995; 91: 103-8. https://doi.org/10.1111/j.1600-0447.1995.tb09748.x
  4. Rosenbaum DH, Siegel M, Barr WB, Rowan AJ. Epileptic aphasia. Neurology 1986; 36: 822-5. https://doi.org/10.1212/WNL.36.6.822
  5. Grimes DA, Guberman A. De novo aphasic status epilepticus. Epilepsia 1997; 38: 945-9. https://doi.org/10.1111/j.1528-1157.1997.tb01262.x
  6. Engel J Jr, Kuhl DE, Phelps ME, Rausch R, Nuwer M. Local cerebral metabolism during partial seizures. Neurology 1983; 33: 400-13. https://doi.org/10.1212/WNL.33.4.400
  7. Dong C, Sriram S, Delbeke D, Al-Kaylani M, Arain AM, Singh P, et al. Aphasic or amnesic status epilepticus detected on PET but not EEG. Epilepsia 2009; 50: 251-5. https://doi.org/10.1111/j.1528-1167.2008.01782.x
  8. Inoue Y, Mihara T, Fukao K, Kudo T, Watanabe Y, Yagi K. Ictal paraphasia induced by language activity. Epilepsy Res 1999; 35: 69-79. https://doi.org/10.1016/S0920-1211(98)00130-2