대한치매학회지 (Dementia and Neurocognitive Disorders)

대한치매학회 (Korean Dementia Association)
권호 표지

Rapidly Progressive Dementia Caused by Neurosyphilis Coinfection with HIV

  • Park, Hee-Kyung (Department of Neurology, Inje University Ilsan Paik Hospital) ;
  • Kim, Hae-Jin (Department of Neurology, Inje University Haeundae Paik Hospital) ;
  • Kim, Sung-Han (Department of Infectious Disease, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Seung-Min (Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jae-Hong (Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine)
  • 발행 : 2010.06.30
⟨ 이전 논문 다음 논문 ⟩

초록

Neurosyphilis occurring among human immunodeficiency virus (HIV)-positive patients has rarely been reported in Korea, although the coexistence of primary or secondary syphilis and HIV has been previously reported. We report a case of a 36-yr-old man who presented with rapidly progressive dementia due to neurosyphilis and HIV coinfection. Syphilis and HIV coinfection should be considered as a differential diagnosis of dementia in young patients since prompt therapeutic intervention could result in good clinical outcome.

키워드

참고문헌

  1. Lynn WA, Lightman S. Syphilis and HIV: a dangerous combination. Lancet Infect Dis 2004; 4: 456-66. https://doi.org/10.1016/S1473-3099(04)01061-8
  2. Poliseli R, Vidal JE, Penalva De Oliveira AC, Hernandez AV. Neurosyphilis in HIV-infected patients: clinical manifestations, serum venereal disease research laboratory titers, and associated factors to symptomatic neurosyphilis. Sexually transmitted diseases 2008; 35: 425-9. https://doi.org/10.1097/OLQ.0b013e3181623853
  3. Kang Y. A normative study of the Korean-mini mental state examination (K-MMSE) in the elderly. The Korean Journal of Psychology 2006; 25: 1-12.
  4. Lee JY, Dong Woo L, Cho SJ, Na DL, Hong Jin J, Kim SK, et al. Brief Screening for Mild Cognitive Impairment in Elderly Outpatient Clinic: Validation of the Korean Version of the Montreal Cognitive Assessment. J Geriatr Psychiatry Neurol 2008; 21: 104-10. https://doi.org/10.1177/0891988708316855
  5. Zetola NM, Engelman J, Jensen TP, Klausner JD. Syphilis in the United States: an update for clinicians with an emphasis on HIV coinfection. Mayo Clin Proc 2007; 82: 1091-102. https://doi.org/10.4065/82.9.1091
  6. Zetola NM, Klausner JD. Syphilis and HIV infection: an update. Clin Infect Dis 2007; 44: 1222-8. https://doi.org/10.1086/513427
  7. Suh MK EK, Ha GY. A case of Human Immunodeficiency Virus Infection Associated with Syphilis. Korean J Dermatol 1994; 32: 498-502.
  8. Almeida OP, Lautenschlager NT. Dementia associated with infectious diseases. Int Psychogeriatr 2005; 17 Suppl 1: S65-77. https://doi.org/10.1017/S104161020500195X
  9. Brightbill TC, Ihmeidan IH, Post MJ, Berger JR, Katz DA. Neurosyphilis in HIV-positive and HIV-negative patients: neuroimaging findings. AJNR Am J Neuroradiol 1995; 16: 703-11.
  10. Yoon JH, Bang OY, Kim HS. Progressive multifocal leukoencephalopathy in AIDS: Proton MR spectroscopy patterns of asynchronous lesions confirmed by serial diffusion-weighted imaging and apparent diffusion coefficient mapping. Journal of Clinical Neurology 2007; 3: 200-3. https://doi.org/10.3988/jcn.2007.3.4.200
  11. Hong YJ, Jung S, Kim JY, Kwon SB, Song KB, Hwang SH, et al. Complete binocular blindness as the first manifestation of HIV-related Cryptococcal meningitis. Journal of Clinical Neurology 2007; 3: 212-4. https://doi.org/10.3988/jcn.2007.3.4.212