Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Haplorchis taichui as a Possible Etiologic Agent of Irritable Bowel Syndrome-Like Symptoms

  • Watthanakulpanich, Dorn (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University) ;
  • Waikagul, Jitra (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University) ;
  • Maipanich, Wanna (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University) ;
  • Nuamtanong, Supaporn (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University) ;
  • Sanguankiat, Surapol (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University) ;
  • Pubampen, Somchit (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University) ;
  • Praevanit, Rangson (Bangkok School of Tropical Medicine, Faculty of Tropical Medicine, Mahidol University) ;
  • Mongkhonmu, Srisuchat (Bangkok School of Tropical Medicine, Faculty of Tropical Medicine, Mahidol University) ;
  • Nawa, Yukifumi (Department of Helminthology, Faculty of Tropical Medicine, Mahidol University)
  • Received : 2010.04.20
  • Accepted : 2010.07.01
  • Published : 2010.09.30
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Abstract

The aim of this study is to clarify the clinical features of Hap/orchis taichui infection in humans in Nan Province, Thailand, and to correlate the clinical features with irritable bowel syndrome (IBS)-like symptoms. In this study area, only H. taichui, but neither other minute intestinal flukes nor small liver flukes were endemic. The degree of infection was determined by fecal egg counts and also by collecting adult worms after deworming. The signs and symptoms of individual patients together with their hematological and biochemical laboratory data were gathered to evaluate the relationship between the clinical features and the severity of infection. Special emphasis was made to elucidate the possible similarities of the clinical features of H. taichui infection and IBS-like symptoms. The results showed useful clinical information and the significant (> 50%) proportion of haplorchiasis patients complained of abdominal pain, lassitude, and flatulence, which were the important diagnostic symptoms of IBS. This study has reported a possible link between H. taichui and IBS, and H. taichui might probably play a role in the etiology of these IBS-like symptoms.

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References

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