대한한의학회지 (The Journal of Korean Medicine)

  • 제31권5호
  • /
  • Pages.12-32
  • /
  • 2010
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  • 1010-0695(pISSN)
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  • 2288-3339(eISSN)
대한한의학회 (The Society of Korean Medicine)
권호 표지

한약물을 이용한 암 치료 관련 무작위 배정 임상시험에 대한 고찰

Review of Randomized Controlled Trials using Herbal Remedies on Cancer Patients

  • 박봉기 (대전대학교 간장면역학교실) ;
  • 왕경화 (대전대학교 간장면역학교실) ;
  • 조정효 (대전대학교 간장면역학교실) ;
  • 손창규 (대전대학교 간장면역학교실)
  • Park, Bong-Ky (Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University) ;
  • Wang, Jing-Hua (Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University) ;
  • Cho, Jung-Hyo (Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University) ;
  • Son, Chang-Gue (Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University)
  • 투고 : 2010.05.03
  • 심사 : 2010.08.11
  • 발행 : 2010.09.30
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초록

Objective: This study aimed to review herbal remedy-based RCTs on cancer patients in order to produce helpful information for clinical study of herbal medicine in the future. Methods: We collected all RCTs using herbal remedies on cancer patients from Pubmed and Cochrane databases until November 1st, 2009. Elementary information such as nation where performed, clinical question, design, randomization, double-blinding and allocation concealment were analyzed. Results: 153 RCTs were finally selected. 119 RCTs were conduced in China while only 2 were done in Korea. The most frequent targeted cancer was lung cancer as 29 RCTs. The main clinical questions included improvement of quality of life, elongation of survival rate and regression of tumor being 83, 62 and 55 respectively. 112 RCTs used herbal remedies with western therapy. Adequate methods for randomization and allocation concealment were found in 37% and 10% of trials respectively. Conclusions: We found that herbal remedies are used on cancer patients in aspects of both caring for the human body and tumor treatment itself. The study might provide us useful data for cancer-related clinical study using herbal remedies in the future.

키워드

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