Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Constituents of Erythrina caffra Stem Bark Grown in Egypt

  • El-Masry, Sawsan (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University) ;
  • Hammoda, Hala M. (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University) ;
  • Zaatout, Hala H. (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University) ;
  • Alqasoumi, Saleh I. (Department of Pharmacognosy, College of Pharmacy, King Saud University) ;
  • Abdel-Kader, Maged S. (Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University)
  • Received : 2010.08.10
  • Accepted : 2010.12.13
  • Published : 2010.12.31
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Abstract

A new 3-indolyl propionate alkaloid; (-) abrine (1), was isolated from the alcohol extract of Erythrina caffra stem bark together with the alkaloid (-) hypaphorine (2). Phytochemical investigation of the chloroform extract led to the isolation of one fatty alcohol; 1-octacosanol, isolated for the first time from genus Erythrina, two dienoid alkaloids; erythraline and erysodine, and three isoflavonoids; 3S (+) 2'-O-methylphaseollidinisoflavan (3), (6aR, 11aR)- 3-hydroxy-10-dimethylallyl-9-methoxypterocarpan, known as sandwicensin (4) and 3R (-) rythbidin A (5). It is worth mentioning that this is the first report for the isolation of these isoflavonoids from E. caffra. The absolute configuration of 3S (+) 2'-O-methylphaseollidinisoflavan (3) was not previously reported. The isolated isoflavonoids showed promising antibacterial activity against Staphylococcus aureus.

Keywords

References

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