Bulletin of the Korean Chemical Society

  • 제31권12호
  • /
  • Pages.3838-3841
  • /
  • 2010
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
권호 표지
DOI QR코드

DOI QR Code

3D QSAR CoMFA Study on Phenylthiazolylhydrazide (PTH) Derivataives as Tau Protein Aggregation Inhibitors

  • Park, Hye-Ri (Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University) ;
  • Kim, Mi-Kyoung (Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University) ;
  • Kim, Dong-Woon (Swine Science Division, National Institute of Animal Science, RDA) ;
  • Choo, Il-Han (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Chong, You-Hoon (Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University)
  • 투고 : 2010.07.28
  • 심사 : 2010.09.29
  • 발행 : 2010.12.20
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

키워드

참고문헌

  1. Hardy, J.; Selkoe, D. J. Science 2002, 297, 353. https://doi.org/10.1126/science.1072994
  2. Vieira, M. N.; Forny-Germano, L.; Saraiva, L. M.; Sebollela, A.; Martinez, A. M.; Houzel, J. C.; De Felice, F. G.; Ferreira, S. T. J. Neurochem. 2007, 103, 736. https://doi.org/10.1111/j.1471-4159.2007.04809.x
  3. Leroy, K.; Bretteville, A.; Schindowski, K.; Gilissen, E.; Authelet, M.; De Decker, R.; Yilmaz, Z.; Buee, L.; Brion, J. P. Am. J. Pathol. 2007, 171, 976. https://doi.org/10.2353/ajpath.2007.070345
  4. Ballatore, C.; Lee, V. M.; Trojanowski, J. Q. Nat. Rev. Neurosci. 2007, 8, 663.
  5. Xia, W. Curr. Opin. Investig. Drugs. 2003, 4, 55.
  6. Wischik, C. M.; Bentham, P.; Wischik, D. J.; Seng, K. M. Alzheimer’s and Dementia 2008, 4, T167.
  7. Bulic, B.; Pickhardt, M.; Khlistunova, I.; Biernat, J.; Mandelkow, E. M.; Mandelkow, E.; Waldmann, H. Angew. Chem. Int. Ed. 2007, 46, 9215. https://doi.org/10.1002/anie.200704051
  8. Pickhardt, M.; von Bergen, M.; Gazova, Z.; Hascher, A.; Biernat, J.; Mandelkow, E.-M.; Mandelkow, E. Curr. Alzheimer Res. 2005, 2, 219. https://doi.org/10.2174/1567205053585891
  9. Larbig, G.; Pickhardt, M.; Lloyd, D. G.; Schmidt, B.; Mandelkow, E. Curr. Alzheimer Res. 2007, 4, 315. https://doi.org/10.2174/156720507781077250
  10. Pickhardt, M.; Larbig, G.; Khlistunova, I.; Coksezen, A.; Meyer, B.; Mandelkow, E.-M.; Schmidt, N.; Mandelkow, E. Biochemistry 2007, 46, 10016. https://doi.org/10.1021/bi700878g
  11. Pickhardt, M.; Biernat, J.; Khlistunova, I.; Wang, Y. P.; Gazova, Z.; Mandelkow, E. M.; Mandelkow, E. Curr. Alzhemier Res. 2007, 4, 397. https://doi.org/10.2174/156720507781788765
  12. Pickhardt, M.; Gazova, Z.; von Bergen, M.; Khlistunova, I.; Wang, Y.; Hascher, A.; Mandelkow, E. M.; Biernat, J.; Mandelkow, E. J. Biol. Chem. 2005, 280, 3628. https://doi.org/10.1074/jbc.M410984200
  13. Necula, M.; Chirita, C. M.; Kuret, J. Biochemistry 2005, 44, 10227. https://doi.org/10.1021/bi050387o
  14. Taniguchi, S.; Suzuki, N.; Masuda, M.; Hisanaga, S.; Iwatsubo, T.; Goedert, M.; Hasegawa, M. J. Biol. Chem. 2005, 280, 7614. https://doi.org/10.1074/jbc.M408714200
  15. Kazius, J.; McGuire, R.; Bursi, R. J. Med. Chem. 2005, 48, 312. https://doi.org/10.1021/jm040835a
  16. SYBYL 7.2 Tripos International, 1699 South Hanley Rd., St. Louis, Missouri, 63144, USA.
  17. Cramer, M.; Cramer, R. D.; Jones, D. M. J. Am. Chem. Soc. 1988, 110, 5959. https://doi.org/10.1021/ja00226a005
  18. Kim, J.; Lee, M.; Kang, S. -Y.; Park, J.; Lim, Y.; Koh, D.; Park, K. H.; Chong, Y. Bull. Korean Chem. Soc. 2006, 27, 1025. https://doi.org/10.5012/bkcs.2006.27.7.1025
  19. Klebe, G.; Abraham, U.; Mietzner, T. J. Med. Chem. 1994, 37, 4130. https://doi.org/10.1021/jm00050a010
  20. Kim, J.; Han, J. H.; Chong, Y. Bull. Korean Chem. Soc. 2006, 27, 1919. https://doi.org/10.5012/bkcs.2006.27.11.1919

피인용 문헌

  1. Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species vol.5, pp.9, 2014, https://doi.org/10.1021/cn500143n
  2. Advances in quantitative structure–activity relationship models of anti-Alzheimer’s agents vol.9, pp.6, 2014, https://doi.org/10.1517/17460441.2014.909404
  3. In Silico Studies in Drug Research Against Neurodegenerative Diseases vol.16, pp.6, 2010, https://doi.org/10.2174/1570159x15666170823095628