References
- Carson DA, Ribeiro JM. Apoptosis and disease. Lancet 1993;341:1251-1254 https://doi.org/10.1016/0140-6736(93)91154-E
- Ohta K, Yamashita N. Apoptosis of eosinophils and lymphocytes in allergic inflammation. J Allergy Clin Immunol 1999;104:14-21 https://doi.org/10.1016/S0091-6749(99)70107-7
- Williams GT. Programmed cell death: apoptosis and oncogenesis. Cell 1991;65:1097-1098 https://doi.org/10.1016/0092-8674(91)90002-G
- Thornberry NA, Rosen A, Nicholson DW. Control of apoptosis by proteases. Adv In Pharmacol 1997;41: 155-177 https://doi.org/10.1016/S1054-3589(08)61058-3
- Green DR and Reed JC. Mitochondria and apoptosis. Science 1998;281:1309-1312 https://doi.org/10.1126/science.281.5381.1309
- Orlowski RZ. The role of the ubiquitin-proteasome pathway in apoptosis. Cell Death Differ 1999;6:303-313 https://doi.org/10.1038/sj.cdd.4400505
- Drexler HC. Activation of the cell death program by inhibition of proteasome function. Proc Natl Acad Sci USA 1997;94:855-860 https://doi.org/10.1073/pnas.94.3.855
- Orlowski RZ, Eswara JR, Lafond-Walker A, Grever MR, Orlowski M, Dang CV. Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res 1998;58:4342-4348
- Meng L, Kwok BH, Sin N, Crews CM. Eponemycin exerts its antitumor effect through the inhibition of proteasome function. Cancer Res 1999;59:2798-2801
- Drexler HC, Risau W, Konerding MA. Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells. FASEB J 2000;14:65-77 https://doi.org/10.1096/fasebj.14.1.65
- Delic J, Masdehors P, Omura S et al. The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radio-resistant human chronic lymphocytic leukemia lymphocytes to TNF-alphainitiated apoptosis. Br J Cancer 1998;77:1103-1107 https://doi.org/10.1038/bjc.1998.183
- Lin ZP, Boller YC, Amer SM et al. Prevention of brefeldin A- induced resistance to teniposide by the proteasome inhibitor MG-132: involvement of NF-kappaB activation in drug resistance. Cancer Res 1998;58:3059-3069
- Adams J. Development of the proteasome inhibitor PS-341. Oncologist 2002;7:9-16
- An WG, Hwang SG, Trepel JB, Blagosklonny MV. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia 2000;14:1276-1283 https://doi.org/10.1038/sj.leu.2401812
- Pasquini LA, Besio Moreno M, Adamo AM, Pasquini JM, Soto EF. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells. J Neurosci Res. Mar 2000;59:601-611 https://doi.org/10.1002/(SICI)1097-4547(20000301)59:5<601::AID-JNR3>3.0.CO;2-1
- Inoue T, Shiraki K, Fuke H et al. Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway. Anticancer Drugs. 2006;17:261-268 https://doi.org/10.1097/00001813-200603000-00004
- Kudo Y, Takata T, Ogawa I et al. p27Kip1 accumulation by inhibition of proteasome function induces apoptosis in oral squamous cell carcinoma cells. Clin Cancer Res 2000;6:916-923
- Takezawa J, Ishimi Y, Yamada K. Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells. Cancer Sci 2008;99: 863-871 https://doi.org/10.1111/j.1349-7006.2008.00764.x
- Shen J, Huang C, Jiang L et al. Enhancement of cisplatin induced apoptosis by suberoylanilide hydroxamic acid in human oral squamous cell carcinoma cell lines. Biochem Pharmacol 2007;73: 1901-1909 https://doi.org/10.1016/j.bcp.2007.03.009
- Adams J, Palombella VJ, Sausville EA et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 1999;59: 2615-2622
- Kim JH, Bae HR, Park BS et al. Early mitochondrial hyperpolarization and intracellular alkalinization in lactacystin-induced apoptosis of retinal pigment epithelial cells. J Pharmacol Exp Ther 2003;305: 474-481 https://doi.org/10.1124/jpet.102.047811
- Wyllie AH, Kerr JF, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980;68: 251-306 https://doi.org/10.1016/S0074-7696(08)62312-8
- Grimm LM, Goldberg AL, Poirier GG, Schwartz LM, Osborne BA. Proteasome play an essential role in thymocyte apoptosis. EMBO J 1996;15:3845-3852
- Li B, Dou QP. Bax degradation by the ubiquitin/ proteasome-dependent pathway: Involvement in tumor survival and progression. Pro Natl Acad Sci USA 2000;97:3850-3855 https://doi.org/10.1073/pnas.070047997
- Kroemer G, Zamzami N, Susin SA. Mitochondrial control of apoptosis. Immunol Today 1997;18:44-51 https://doi.org/10.1016/S0167-5699(97)80014-X
- Susin SA, Lorenzo HK, Zamzami N et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999;397:441-446 https://doi.org/10.1038/17135
- Orrenius S. Mitochondrial regulation of apoptotic cell death. Toxicol Lett 2004;149:19-23 https://doi.org/10.1016/j.toxlet.2003.12.017
- Barczyk K, Kreuter M, Pryjma J et al. Serum cytochrome c indicates in vivo-apoptosis and it can serve as a prognostic marker during cancer therapy. In. J Cancer 2005;114:167–173
- Brouckaert G, Kalai M, Saelens X, Vandenabeele P. Apoptotic Pathways and Their Regulation. In: Los, M., Gibson, S.B. (Eds.), Apoptotic Pathways as Target for Novel Therapies in Cancer and Other Diseases. New York. 2005, Springer Academic Press
- Hengartner MO. The biochemistry of apoptosis. Nature 2000;407:770-776 https://doi.org/10.1038/35037710
- Hunter JJ, Parslow TG. A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis. J Biol Chem 1996;271:8521-8524 https://doi.org/10.1074/jbc.271.15.8521
- Narita M, Shimizu S, Ito T et al. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria.Proc Natl Acad Sci U S A. 1998;95:14681-14686 https://doi.org/10.1073/pnas.95.25.14681
- Wagenknecht B, Hermission M, Groscurth P, Liston P, Krammer PH, Weller M. Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release. J Neurochem 2000;75:2288-2297 https://doi.org/10.1046/j.1471-4159.2000.0752288.x
- Marshansky V, Wang X, Bertrand R et al. Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J Immunol 2001;166:3130-3142 https://doi.org/10.4049/jimmunol.166.5.3130
- Li P, Nijhawan D, Budihardjo I et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489 https://doi.org/10.1016/S0092-8674(00)80434-1
- Zou H, Li Y, Liu X, Wang, X. An APAF-1, cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 1999;274:11549–11556 https://doi.org/10.1074/jbc.274.17.11549
- Dauglas E, Susin SA, Zamzami N et al. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000;14:729-739 https://doi.org/10.1096/fasebj.14.5.729
- Thornberry NA, Lazebnik Y. Caspase: Enemies within. Science 1998;28:1312-1316
- Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, Akey CW. Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation. Mol Cell 2002;9:423-432 https://doi.org/10.1016/S1097-2765(02)00442-2
- Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999;13:1899-1911 https://doi.org/10.1101/gad.13.15.1899
- Porter AG. Protein translocation in apoptosis. Trends Cell Biol 1999;9:394-401 https://doi.org/10.1016/S0962-8924(99)01624-4
- Cheng AC, Jian CB, Huang YT, Lai CS, Hsu PC, Pan MH. Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells. Food Chem Toxicol 2007;45:2206-2218 https://doi.org/10.1016/j.fct.2007.05.016
- Pavletich NP. Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J Mol Biol. 1999;287: 821-828 https://doi.org/10.1006/jmbi.1999.2640
- Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, Schreiber SL. Inhibition of proteasome activities and subunit specific-amino terminal threonine modification by lactocystin. Science 1995;268:726–731 https://doi.org/10.1126/science.7732382
- Shinohara K, Tomioka M, Nakano H, Tone S, Ito H, Kawashima S. Apoptosis induction resulting from proteasome inhibition. Biochem J 1996;317:385-388 https://doi.org/10.1042/bj3170385
- Meriin AB, Gabai VL, Yaglom J, Shifrin VI, Sherman MY. Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis. J Biol Chem 1998;273:6373-6379 https://doi.org/10.1074/jbc.273.11.6373
- Elledge S, Harper W. Cdk inhibitors: on the threshold of checkpoints and development. Curr Op Cell Biol 1994;6:847–852 https://doi.org/10.1016/0955-0674(94)90055-8
- Pagano M, Tam SW, Theodoras AM et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995;269:682–685 https://doi.org/10.1126/science.7624798