Nuclear Medicine and Molecular Imaging

The Korean Society of Nuclear Medicine (대한핵의학회)
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Intra-abdominal Kikuchi's Disease Mimicking Malignant Lymphoma on FDG PET-CT

FDG PET-CT에서 악성림프종처럼 보이는 복부 기쿠치병

  • Han, Hye-Suk (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Kim, Gi-Hyun (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Cho, Young-Shim (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Joo, Hye-Jin (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Lee, Ok-Jun (Department of Pathology, Chungbuk National University College of Medicine) ;
  • Ryu, Dong-Hee (Department of Surgery, Chungbuk National University College of Medicine) ;
  • Lee, Ki-Hyeong (Department of Internal Medicine, Chungbuk National University College of Medicine) ;
  • Kim, Seung-Taik (Department of Internal Medicine, Chungbuk National University College of Medicine)
  • 한혜숙 (충북대학교 내과학교실) ;
  • 김기현 (충북대학교 내과학교실) ;
  • 조영심 (충북대학교 내과학교실) ;
  • 주혜진 (충북대학교 내과학교실) ;
  • 이옥준 (충북대학교 병리학교실) ;
  • 류동희 (충북대학교 외과학교실) ;
  • 이기형 (충북대학교 내과학교실) ;
  • 김승택 (충북대학교 내과학교실)
  • Published : 2009.08.30
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Abstract

Kikuchi's disease is a self-limiting benign disease characterized by cervical lymphadenopathy, but it can be mistaken for malignant disease, and when involved lymph nodes are unusually located, diagnosis can be more difficult. The authors report the case of a 19-year-old man with Kikuchi's disease, who had isolated intra-abdominal lymphadenopathy and increased 18-fluoro-deoxyglucose (FDG) uptake in positron emission tomography-computed tomography (PET-CT). Although its incidence is extremely rare, intra-abdominal Kikuchi's disease with increased FDG uptake in PET-CT image should be considered in the differential diagnosis when constitutional symptoms mimic those of malignant lymphoma.

Keywords

References

  1. Liao AC, Chen YK. Cervical lymphadenopathy caused by Kikuchi disease: positron emission tomographic appearance. Clin Nucl Med 2003;28:320-1 https://doi.org/10.1097/00003072-200304000-00013
  2. Kim CH, Hyun O J, Yoo IeR, Kim SH, Sohn HS, Chung SK. Kikuchi Disease Mimicking Malignant Lymphoma on FDG PET/CT. Clin Nucl Med 2007;32:711-2 https://doi.org/10.1097/RLU.0b013e3181250346
  3. Kaicker S, Gerard PS. Kalburgi S, Geller MD, Hailoo D. PET-CT scan in a patient with Kikuchi disease. Pediatr Radiol 2008;38:596-7 https://doi.org/10.1007/s00247-007-0742-4
  4. Turner RR, Martin J, Dorfman RF, Necrotizing lymphadenitis, A study of 30 cases. Am J Surg Pathol 1983;7:115-23 https://doi.org/10.1097/00000478-198303000-00001
  5. Dorfman RF, Berry GJ. Kikuchi's histiocytic necrotizing lymphadenitis: an analysis of 108 cases with emphasis on differential diagnosis. Sellin Diagn Pathol 1988;5:329-45
  6. Rudin C, Wernli R, Rutishauser M, Ohnacker H. Mesenterial histiocytic necrotizing lymphadenitis. Case report. Helv Paediatr Acta 1987;42:35-40
  7. McLoughlin J, Creagh T, Taylor A, Lampert I. Kikuchi's disease simulating acute appendicitis. Br J Surg 1988;75:1206 https://doi.org/10.1002/bjs.1800751220
  8. Rudniki C, Kessler E. Zarfati M, Turani H, Bar-Ziv Y, Zahavi I. Kikuchi's necrotizing lymphadenitis: a cause of fever of unknown origin and splenomegaly. Acta Haematol 1988;79:99-102 https://doi.org/10.1159/000205730
  9. Kita Y, Kikuchi M, Nakae T, Nakai Y, Okamura A, Ohshima T, et al. A case of Kikuchi's disease with abdominal manifestations, Surgery 1977;122:962-3 https://doi.org/10.1016/S0039-6060(97)90338-X
  10. Oh BJ, Choi WJ, Lim KS, Kim W. Kikuchi-Fujimoto disease: three cases presenting as acute abdomen. J Korean Soc Emerg Med 2005;16:194-9