The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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A Study on Active Oxygen and Antioxidant capacity of Qi Deficiency and Blood Deficiency Animal Model

기허(氣虛), 혈허(血虛) 동물모델에서의 활성산소 및 항산화력 연구

  • 전선우 (경희대학교 한의과대학 안이비인후피부과학 교실) ;
  • 김윤범 (경희대학교 한의과대학 안이비인후피부과학 교실)
  • Published : 2009.08.25
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Abstract

Background and Objective : There are a lot of theories that explained the aging process, and the oxidative stress is one of the important theory that explained the aging process. The aim of this study was to investigate active oxygen and antioxidant capacity of Qi deficiency and Blood deficiency animal models. Material and Methods : Sprague-Dawley rats were divided into three groups: normal group, Qi deficiency group and Blood deficiency group. The Qi deficiency animal model was induced through restriction of food (12g/kg/day) for 20 days. Blood deficiency animal model was induced by bleeding from tail vein(0.4ml/time) 8 times. The normal animal model was kept without any intervention. The oxidative stress was observed by measuring the active oxygen and antioxidant capacity. Results and Conclusion : 1. Active oxygen was significantly increased in the Qi deficiency group and Blood deficiency group. (P=0.061) 2. Antioxidant capacity was increased in the Qi deficiency group and Blood deficiency group. But there is no significant difference. (P=0.113)

Keywords

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