Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지
DOI QR코드

DOI QR Code

A Case of Non-small Cell Lung Cancer Presenting as Abdominal Pain and a Pancreatic Nodule

복통과 췌장결절로 발현한 비소세포폐암 1예

  • Koh, Kyung Won (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kim, Hyeon Tae (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Jang, Sang Eon (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kim, Yeo Myeong (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Jin, Min-Sun (Department of Pathology, Korea Cancer Center Hospital) ;
  • Kim, Sang Bum (Department of General Surgery, Korea Cancer Center Hospital) ;
  • Kim, Hye-Ryoun (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kim, Cheol Hyeon (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Lee, Jae Cheol (Department of Internal Medicine, Korea Cancer Center Hospital)
  • Received : 2009.06.04
  • Accepted : 2009.06.30
  • Published : 2009.07.30
Download PDF
⟨ Previous Next ⟩

Abstract

Lung cancer frequently metastasizes to distant organs. However, solitary metastasis to the pancreas, with lung cancer as the source, is very rare. Most metastatic cases of the pancreas tend to be discovered in patients with widely disseminated malignant disease. In addition, patients with pancreatic metastases are often asymptomatic, the metastatic lesions are found incidentally, and are misdiagnosed as primary pancreatic tumors. We described the case of a 63-year-old man who presented with abdominal pain and a pancreatic nodule. The patient underwent resection of primary lung cancer followed by pylorus preserving pancreatoduodenectomy. The pancreatic nodule was confirmed as a solitary metastasis from lung cancer.

저자들은 복통으로 내원한 환자에서 발견된 췌장 결절이 수술을 통하여 비소세포폐암의 단일성 췌장전이로 확진 되었던 드문 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

  1. Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma: analysis of 1000 autopsied cases. Cancer 1950;3:74-85 https://doi.org/10.1002/1097-0142(1950)3:1<74::AID-CNCR2820030111>3.0.CO;2-7
  2. Nakamura E, Shimizu M, Itoh T, Manabe T. Secondary tumors of the pancreas: clinicopathological study of 103 autopsy cases of Japanese patients. Pathol Int 2001;51:686-90 https://doi.org/10.1046/j.1440-1827.2001.01258.x
  3. Adsay NV, Andea A, Basturk O, Kilinc N, Nassar H, Cheng JD. Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchows Arch 2004;444:527-35
  4. Maeno T, Satoh H, Ishikawa H, Yamashita YT, Naito T, Fujiwara M, et al. Patterns of pancreatic metastasis from lung cancer. Anticancer Res 1998;18:2881-4
  5. Lankisch PG, Löhr A, Kunze E. Acute metastasis- induced pancreatitis in bronchial carcinoma. Dtsch Med Wochenschr 1987;112:1335-7 https://doi.org/10.1055/s-2008-1068245
  6. Z’Graggen K, Fernández-del Castillo C, Rattner DW, Sigala H, Warshaw AL. Metastases to the pancreas and their surgical extirpation. Arch Surg 1998;133:413-7; discussion 418-9 https://doi.org/10.1001/archsurg.133.4.413
  7. Moazzam N, Mir A, Potti A. Pancreatic metastasis and extrahepatic biliary obstruction in squamous cell lung carcinoma. Med Oncol 2002;19:273-6 https://doi.org/10.1385/MO:19:4:273
  8. Garcia Vidal C, Carrillo E, Barreiro B. Solitary metastasis to the pancreas in a patient with lung cancer. Arch Bronconeumol 2003;39:601 https://doi.org/10.1157/13054365
  9. Furak J, Farkas G, Trojan I, Szoke T, Tiszlavicz L. Pancreas resection for lung cancer metastasis. Magy Seb 2003;56:209-10
  10. Liratzopoulos N, Efremidou EI, Papageorgiou MS, Romanidis K, Minopoulos GJ, Manolas KJ. Extrahepatic biliary obstruction due to a solitary pancreatic metastasis of squamous cell lung carcinoma: case report. J Gastrointestin Liver Dis 2006;15:73-5
  11. Perfetti V, Markopoulos K, Maffè GC, Picheo R, Corazza GR. Juxtapapillary pancreatic metastasis with obstructive jaundice as isolated recurrence of lung adenocarcinoma. Dig Liver Dis 2008;40:230-1 https://doi.org/10.1016/j.dld.2007.11.008
  12. Pericleous S, Mukherjee S, Hutchins RR. Lung adenocarcinoma presenting as obstructive jaundice: a case report and review of literature. World J Surg Oncol 2008;6:120 https://doi.org/10.1186/1477-7819-6-120
  13. Mori N, Sawada T, Satoh H, Kawaguchi M, Hara H, Matsushita K. A resected case of solitary pancreatic metastasis from adenocarcinoma of the lung. JOP 2008; 9:698-703
  14. Wilson RL, Brown RK, Reisman D. Surgical resection for metastatic non-small cell lung cancer to the pancreas. Lung Cancer 2009;63:433-5 https://doi.org/10.1016/j.lungcan.2008.09.012
  15. Magilligan DJ Jr, Duvernoy C, Malik G, Lewis JW Jr, Knighton R, Ausman JI. Surgical approach to lung cancer with solitary cerebral metastasis: twenty-five years' experience. Ann Thorac Surg 1986;42:360-4 https://doi.org/10.1016/S0003-4975(10)60536-X
  16. Luketich JD, Burt ME. Does resection of adrenal metastases from non-small cell lung cancer improve survival? Ann Thorac Surg 1996;62:1614-6 https://doi.org/10.1016/S0003-4975(96)00611-X
  17. Crippa S, Angelini C, Mussi C, Bonardi C, Romano F, Sartori P, et al. Surgical treatment of metastatic tumors to the pancreas: a single center experience and review of the literature. World J Surg 2006;30:1536-42 https://doi.org/10.1007/s00268-005-0464-4

Cited by

  1. Clinical Characteristics of Pancreatic Metastases vol.57, pp.6, 2009, https://doi.org/10.4166/kjg.2011.57.6.358