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미만성 폐포 출혈을 동반한 급성 담낭염으로 발현한 Churg-Strauss 증후군 1예

A Case of Churg-Strauss Syndrome with Diffuse Alveolar Hemorrhage Presenting as Acute Acalculous Cholecystitis

  • 김지은 (부산대학교 의과대학 내과학교실) ;
  • 김기욱 (부산대학교 의과대학 내과학교실) ;
  • 박혜경 (부산대학교 의과대학 내과학교실) ;
  • 전두수 (부산대학교 의과대학 내과학교실) ;
  • 김윤성 (부산대학교 의과대학 내과학교실) ;
  • 이민기 (부산대학교 의과대학 내과학교실) ;
  • 박순규 (부산대학교 의과대학 내과학교실)
  • Kim, Ji Eun (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Kim, Ki Uk (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Park, Hye-Kyung (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Jeon, Doo Soo (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Kim, Yun Sung (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Lee, Min Ki (Department of Internal Medicine, Pusan National University College of Medicine) ;
  • Park, Soon Kew (Department of Internal Medicine, Pusan National University College of Medicine)
  • 투고 : 2009.01.06
  • 심사 : 2009.03.06
  • 발행 : 2009.03.30

초록

저자들은 복통을 주소로 내원하여 급성 무결석 담낭염으로 진단받고 치료 중 미만성 폐포 출혈이 발생한 Churg-Strauss 증후군 환자 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Churg-Strauss syndrome (CSS) is a disorder that is characterized by asthma, hypereosinophilia and systemic vasculitis affecting a number of organs. The manifestations of acute cholecystitis and diffuse alveolar hemorrhage are rarely reported in CSS. A 22-year-old woman with bronchial asthma visited our hospital complaining of right upper quadrant pain with a sudden onset. The abdominal computed tomography (CT) scan revealed gall bladder edema consistent with acute cholecystitis. On the initial evaluation, marked hypereosinophilia was observed in the peripheral blood smear. The nerve conduction velocity measurements and a skin biopsy performed to confirm the organ involvement of disease indicated typical mononeuritis multiplex and necrotizing vasculitis, respectively, which was complicated with CSS. On the 12th hospital day, ground glass opacity and consolidations were newly developed on both lung fields. The bronchoalveolar lavage (BAL) fluid showed increasing bloody return in sequential aliquots that were characteristic of a diffuse alveolar hemorrhage. We report a case of CSS with acute cholecystitis and diffuse alveolar hemorrhage.

키워드

참고문헌

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피인용 문헌

  1. Churg-Strauss syndrome presenting as acute acalculous cholecystitis vol.1, pp.4, 2009, https://doi.org/10.4168/aard.2013.1.4.388
  2. Churg-Strauss Syndrome Presenting with Diffuse Alveolar Hemorrhage vol.89, pp.6, 2015, https://doi.org/10.3904/kjm.2015.89.6.738