Effects of Short-Term Ingestion of Wood Vinegar on Antioxidative Defense System in Trained Rats

목초액 단기섭취가 훈련된 흰쥐의 항산화 방어기전에 미치는 영향

  • Lee, Soo-Chun (Lab of Exercise Nutrition, Dept. of Physical Education, Kyungpook National University) ;
  • Kim, Dong-Ki (Lab of Exercise Nutrition, Dept. of Physical Education, Kyungpook National University) ;
  • Kim, Jae-Woo (Lab of Exercise Nutrition, Dept. of Physical Education, Kyungpook National University) ;
  • Seo, Hyo-Bin (Lab of Exercise Nutrition, Dept. of Physical Education, Kyungpook National University) ;
  • Lee, Yoon-Kyung (Lab of Exercise Nutrition, Dept. of Physical Education, Kyungpook National University) ;
  • Jeon, Byung-Duk (Lab of Exercise Nutrition, Dept. of Physical Education, Kyungpook National University) ;
  • Lee, Dong-Woon (Dept. of Applied Biology, Kyungpook National University) ;
  • Ryu, Sung-Pil (Dept. of Leisure Sports, Kyungpook National University)
  • 이수천 (경북대학교 운동영양학 연구실) ;
  • 김동기 (경북대학교 운동영양학 연구실) ;
  • 김재우 (경북대학교 운동영양학 연구실) ;
  • 서효빈 (경북대학교 운동영양학 연구실) ;
  • 이윤경 (경북대학교 운동영양학 연구실) ;
  • 전병덕 (경북대학교 운동영양학 연구실) ;
  • 이동운 (경북대학교 생물응용학과) ;
  • 류승필 (경북대학교 레저스포츠학과)
  • Published : 2009.08.30

Abstract

The purpose of this study is to know the effect of wood vinegar ingestion on antioxidative defense system in trained rats. Twenty-eight male Sprague-Dawley male rats were used as the subject. Experimental groups were divided into CON-SED(control + sedentary), CON-EX(control + exercise), WV-SED(wood vinegar ingestion + sedentary), and WV-EX(wood vinegar ingestion + exercise), respectively. Body weight and stored fat weight(mesentery, retroperitoneal and epididymal) were not significantly differed in each group. Concentration of TG and FFA was not differed by wood vinegar ingestion. Concentration of glucose was revealed significant difference in exercise group rather than sedentary group, but there was no difference by wood vinegar ingestion between the groups. Contents of SOD in WV-EX group was significantly higher than other three groups. Contents of MDA in CON-EX group was significantly lower than CON-SED group, while the difference between CON group and WV group was not observed. In conclusion, wood vinegar ingestion with exercise seems to have a positive beneficial effects on reducing oxidative stress.

본 연구는 목초액의 섭취가 훈련된 흰쥐의 항산화방어기전에 미치는 영향을 알아보기 위하여 수행되었다. 실험대상으로는 Sprague-Dawley계 수컷 흰쥐를 사용하였는데 실험그룹은 비운동 대조군과 운동 대조군, 목초액 섭취 비 운동 대조군, 목초액 섭취 운동 대조군으로 나누어 수행하였는데 체중과 혈중성분 변화, 글리코겐 함량, SOD 활성 수준, MDA 함량에 관한 분석을 하였다. 체중과 체지방(장간막, 복막후, 부고환)은 각 그룹 간에 유의한 차이가 없었고, TG와 FFA 농도도 목초액 섭취로 인한 차이는 없었다. Glucose 농도는 대조군 보다 운동군에서 유의한 차이를 나타내었으나 목초액 섭취로 인한 차이는 없었다. 목초액 투여 운동군에서의 SOD 활성은 다른 그룹보다 유의하게 높았다. 운동 대조군에서의 MDA 함량은 비운동 대조군보다 유의하게 낮게 나타났으나 대조군과 목초액 투여군 간의 차이는 없었다. 결론적으로 운동과 목초액 섭취는 산화적 스트레스의 감소에 긍정적인 영향을 줄 것으로 예상된다.

Keywords

References

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