The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Comparative Studies on the Anti-oxidation Activities of Aralia continentalis Root and Angelica pubescens Root

한국독활(韓國獨活)과 중국독활(中國獨活)의 항산화효능 비교 연구

  • Shin, Myoung-Soup (Dept of Herbology, College of Oriental Medicine, Kyungwon University) ;
  • Han, Hyo-Sang (Dept of Herbology, College of Oriental Medicine, Kyungwon University) ;
  • Lee, Young-Jong (Dept of Herbology, College of Oriental Medicine, Kyungwon University)
  • 신명섭 (경원대학교 한의과대학 본초학교실) ;
  • 한효상 (경원대학교 한의과대학 본초학교실) ;
  • 이영종 (경원대학교 한의과대학 본초학교실)
  • Published : 2009.06.30
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Abstract

Objectives : The present study compared Aralia continentalis Root and Angelica pubescens Root used in Korea and China respectively concerning their anti-oxidant effect Methods : We tested the anti-oxidant effect through in vitro experiment and in vivo experiment that induced oxidative stress using ethanol. Results : 1. DPPH scavenging activity was stronger in Aralia continentalis Root than in Angelica pubescens Root 2. Superoxide anion radical scavenging activity was similar between Aralia continentalis Root and Angelica pubescens Root 3. The linoleic acid peroxidation inhibition effect was stronger in Aralia continentalis Root than in Angelica pubescens Root. 4. The phenolic component was higher in Aralia continentalis Root than in Angelica pubescens Root. 5. Both Aralia continentalis Root and Angelica pubescens Root increased the concentration of GSH and decreased SOD activity in mice, in which oxidative stress was induced, and the effect was stronger in Aralia continentalis Root. 6. Aralia continentalis Root increased GSH peroxidase activity but Angelica pubescens Root did not have such an effect. 7. Neither Aralia continentalis Root nor Angelica pubescens Root had a significant effect on catalase, ADH and ALDH in mice, in which oxidative stress was induced. Conclusions : Aralia continentalis Root has a stronger anti-oxidant effect than Angelica pubescens Root. Thus, although Aralia continentalis Root is not an original plant recorded in botanical literature, it may be usable based on the data about its effects.

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References

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