Journal of the Korean Academy of Child and Adolescent Psychiatry

Korean Academy of Child and Adolescent Psychiatry (대한소아청소년정신의학회)
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Event-Related Potentials During the Visual Go/NoGo Task in Drug-Naive Boys with Attention-Deficit/Hyperactivity Disorder

약물 복용력이 없는 주의력결핍 과잉행동장애 남아의 시각적 Go/NoGo 과제 수행결과 및 수행시의 사건관련전위

  • Kim, Kun-Woo (Department of Psychiatry, College of Medicine University of Ulsan, Asan Medical Center) ;
  • Lee, Jung-Sun (Department of Psychiatry, College of Medicine University of Ulsan, Asan Medical Center) ;
  • Park, Su-Bin (Department of Psychiatry, College of Medicine University of Ulsan, Asan Medical Center) ;
  • Hong, Jin-Pyo (Department of Psychiatry, College of Medicine University of Ulsan, Asan Medical Center) ;
  • Kim, Seong-Yoon (Department of Psychiatry, College of Medicine University of Ulsan, Asan Medical Center) ;
  • K.Yoo, Han-Ik (Department of Psychiatry, College of Medicine University of Ulsan, Asan Medical Center)
  • 김건우 (울산대학교 의과대학 서울아산병원 정신과학교실) ;
  • 이중선 (울산대학교 의과대학 서울아산병원 정신과학교실) ;
  • 박수빈 (울산대학교 의과대학 서울아산병원 정신과학교실) ;
  • 홍진표 (울산대학교 의과대학 서울아산병원 정신과학교실) ;
  • 김성윤 (울산대학교 의과대학 서울아산병원 정신과학교실) ;
  • 유한익 (울산대학교 의과대학 서울아산병원 정신과학교실)
  • Published : 2009.06.30
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Abstract

Objectives: The purpose of this study was to examine the performance and electrophysiological characteristics of drug-naive children with attention-deficit/hyperactivity disorder(ADHD) during the Go/NoGo task. Methods: Twenty-three boys with ADHD and 18 age-matched normal boys were recruited at a child psychiatric outpatient clinic in Seoul. All subjects were assessed by the Kiddie Schedules for Affective Disorders and Schizophrenia Present and Lifetime version. The investigator also assessed all subjects using the ADHD Rating Scale-IV(ADHDRS). Event-related potentials were recorded from 8 scalp electrodes during the visual Go/NoGo task. Results: Children with ADHD showed a larger mean of standard deviation of response time during the Go/NoGo task than normal children. The temporal N200 and P300 amplitudes were larger in children with ADHD relative to controls. The parietal N200 and P300 latencies were more prolonged in children with ADHD compared to normal controls. Conclusion: These results suggest that psychotropic-naive children with ADHD may have more variable performance ability, more difficulty in discriminating visual stimuli, and slower information processing speed than their normal age-matched counterparts.

Keywords

References

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