Lower Leg Amputation by Calciphylaxis in Diabetic Nephropathy Patient (A Case Report)

당뇨병성 신부전증 환자의 선단 궤양에 의한 하지절단(1예 보고)

  • Lee, Jun-Young (Department of Orthopaedic Surgery, College of Medicine, Chosun University) ;
  • Yu, Jae-Cheol (Department of Orthopaedic Surgery, College of Medicine, Chosun University)
  • 이준영 (조선대학교 의과대학 정형외과학교실) ;
  • 유재철 (조선대학교 의과대학 정형외과학교실)
  • Published : 2009.06.15

Abstract

Calciphylaxis is a rare disease that appear in patients with secondary hyper-parathyroidism or chronic renal failure or that show defect in calcium phosphate metabolism which is characterized by fibrin deposit or calcification of medial wall of vessels causing gradual ischemic skin necrosis. Calciphylaxis is a disease with poor prognosis as skin necrosis can progress rapidly. If left untreated, calciphylaxis will progress to sepsis with high mortality. The treatment is controversial but kidney transplantation or parathyroidectomy is suggested to recover calcium-phosphate metabolism. The authors have experienced calciphylaxis in a patient with chronic renal failure caused by DM nephropathy with characteristic skin lesion and rapid skin necrosis. We describe this case with documentary reviews.

Keywords

References

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