The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Study on the Obesity and Blood parameters Differences between Fire/Heat and Qi-deficiency Pattern Identification/Syndrome Differentiation among Acute Stroke Patients

급성기 중풍환자에서 비만 및 혈액지표의 기허 및 화열 변증의 차이에 대한 고찰

  • Cha, Min-Ho (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Kim, So-Yeon (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Lim, Ji-Hye (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Kang, Byung-Kab (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Koo, Mi-Mi (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Kim, No-Soo (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Lee, Jeong-Sub (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine) ;
  • Bang, Ok-Sun (Brain Disease Research Center, Division of TKM Integrated Research, Korea Institute of Oriental Medicine)
  • 차민호 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 김소연 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 임지혜 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 강병갑 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 고미미 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 김노수 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 이정섭 (한국한의학연구원 한의융합연구본부 뇌질환연구센터) ;
  • 방옥선 (한국한의학연구원 한의융합연구본부 뇌질환연구센터)
  • Published : 2009.12.30
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Abstract

Object : In the present study, we investigated the obesity and blood parameters between Qi-deficiency and Fire/Heat pattern identification/syndrome differentiation (PI/SD) in acute stroke patients. Materials and Methods : A total of 391 stroke patients within 7 days after onset were consecutively recruited from 12 hospitals across South Korea from Nov. 1st, 2006 to Jun. 31st, 2009. They were diagnosed as Fire/Heat or Qi-deficiency among five PI/SD subtypes by two independent stroke experts. We investigated the differences of obesity and blood characteristics between Fire/Heat and Qi-deficiency by statistical analyses. Results : In male subjects, obesity was significantly associated with Fire/Heat PI/SD. The averaged mean BMI ($24.13kg/m^2$) and waist circumference(89.34cm) of the Fire/Heat group were higher than those of the Qi-deficiency group ($22.60kg/m^2$ and 83.43 cm, respectively). The number of obese patients was larger in the Fire/Heat group than in the Qi-deficiency group (p = 0.001). Hyperlipidemia was also related with Fire/Heat. However, obesity was not associated with PI/SD in female subjects where the number of hyperlipidemic patients was higher in the Qi-deficiency group. Among blood parameters, the levels of triglycerides and fasting blood sugar were higher in the Fire/Heat group compared with the Qi-deficiency group in male subjects. However, total cholesterol of the Qi-deficiency group was higher than in the Fire/Heat group among female subjects. Conclusion : This study shows that obesity and hyperlipidemia are significantly difference between Qi-deficiency and Fire/Heat. We suggests that PI/SD may be associated with clinical characteristics and large population study between PI/SD and clinical characteristics including blood parameters are needed.

Keywords

Acknowledgement

Supported by : 한국한의학연구원

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