Polymer(Korea) (폴리머)

The Polymer Society of Korea (한국고분자학회)
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Synthesis of Poly(benzyl ether) Dendrimers by Click Chemistry

클릭 화학에 의한 폴리(벤질에테르)덴드리머의 효율적인 합성

  • Lee, Jae-Wook (Department of Chemistry, Dong-A University) ;
  • Lee, Un-Yup (Department of Chemistry, Dong-A University) ;
  • Han, Seung-Choul (Department of Medical Bioscience, Dong-A University) ;
  • Kim, Ji-Hyeon (Department of Chemical and Bio Engineering, Kyungwon University) ;
  • Jin, Sung-Ho (Department of Chemistry Education & Center for Plastic Information System, Pusan National University)
  • Published : 2009.01.25
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Abstract

The stitching method for the synthesis of $Fr\acute{e}chet$-type dendrimers was elaborated using click chemistry between an alkyne and an azide. The core building block, 4,4'-(3,5-bis(azidopropyloxy)benzyloxy)bisphenyl, was designed to serve as the azide functionalities for dendrimer growth via click reactions with the alkyne-dendrons. The synthetic strategy involved an 1,3-dipolar cycloaddition reaction between an azide and an alkyne-functionalized $Fr\acute{e}chet$-type dendrons in the presence of Cu(I) species which is known as the best example of click chemistry.

프레체형태 덴드리머의 합성을 위한 연결 방법이 알카인기와 아지드기 사이의 클릭 화학을 이용하여 개발되었다. 덴드리머의 핵으로 작용할 수 있는 단위체인 4,4'-(3,5-비스(아지도프로필옥시)벤질옥시)비스페닐이 알카인덴드론과 클릭 반응을 통해 덴드리머의 구축을 위해 사용되었다. 즉, 구리촉매 존재하에서 다중(아지드)화합물과 말단 알킨기를 가지는 폴리(벤질에테르)덴드론 사이치 클릭 반응을 통해 덴드리머의 합성 전략이 완성되었다.

Keywords

References

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