The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지

Chronic Iron Deficiency Anemia Treated with Bojungicki-tang : A Case Report

  • Son, Chang-Gue (Dept. of Internal Medicine of Oriental Medical College in Dae-jeon University)
  • Published : 2009.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objective : To expend the oriental medicine-based strategies or therapeutics for anemia, including iron deficiency anemia. Methods : A 23 year-old man suffering from severe and chronic iron deficiency anemia was believed to have disorder of iron absorption. He had neither specific medical cause nor positive response to western treatments. Blood and biochemical parameters such as levels of hemoglobin, ferritin, transferrin and serum iron were serially chased during treatments. Result : Bojungicki-tang was given to the patient based on diagnosis as a deficiency of spleen qi. The hemoglobin level was normalized along with administration of Bojungicki-tang. Also, the distortions of biochemical indicators (ferritin, transferrin and serum iron) reached a normal range within three months. Conclusion : Bojungicki-tang could be a curing remedy for iron deficiency anemia caused by problems in iron absorption if symptom-differentiation has deficiency of spleen qi.

Keywords

References

  1. Brady PG. Iron deficiency anemia : a call for aggressive diagnostic evaluation. South. Med. J. 2007;100(10):966-7. https://doi.org/10.1097/SMJ.0b013e3181520699
  2. Calis JC, Phiri KS, Faragher EB. Severe anemia in Malawian children. N. Engl. J. Med. 2008;358(9):888-99. https://doi.org/10.1056/NEJMoa072727
  3. Rockey D, Cello J. Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia. N Engl J Med.1993;329(23):1691-5. https://doi.org/10.1056/NEJM199312023292303
  4. Eisenstaedt R, Penninx BW, Woodman RC. Anemia in the elderly: current understanding and emerging concepts. Blood Rev. 2006;20(4) :213-26. https://doi.org/10.1016/j.blre.2005.12.002
  5. Wells CW, Lewis S, Barton JR, Corbett S. Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients. Inflamm Bowel Dis. 2006;12(2):123-30. https://doi.org/10.1097/01.MIB.0000196646.64615.db
  6. Cook JD. Iron-deficiency anaemia. Baillieres Clin. Haematol. 1994;7(4):787-804. https://doi.org/10.1016/S0950-3536(05)80124-6
  7. Clark SF. Iron deficiency anemia. Nutr Clin Pract. 2008;23(2):128-41. https://doi.org/10.1177/0884533608314536
  8. Von Garnier C, Stuenitz H, Decker M, Battegay E, Zeller A. Pica and refractory iron deficiency anaemia: a case report. J Med Case Reports. 2008;2(1):324. https://doi.org/10.1186/1752-1947-2-324
  9. Alleyne M, Horne MK, Miller JL. Individualized treatment for iron-deficiency anemia in adults. Am J Med. 2008;121(11):943-8. https://doi.org/10.1016/j.amjmed.2008.07.012
  10. West AR, Oates PS. Mechanisms of hemeiron absorption: current questions and controversies. World J Gastroenterol. 2008;14(26):4101-10. https://doi.org/10.3748/wjg.14.4101
  11. Cook JD, Skikne BS, Lynch SR, Reusser ME. Estimates of iron sufficiency in the US population. Blood. 1986;68(3):726-31.
  12. Kappas A, Drummond GS, and Galbraith RA. Prolonged clinical use of a heme oxygenase inhibitor: hematological evidence for an inducible but reversible iron-deficiency state. Pediatrics. 1993;91:537-539
  13. Arosio P, Yokota M, Drysdale JW. Characterization of serum ferritin in iron overload: possible identity to natural apoferritin. Br J Haematol. 1977;36(2):199-207. https://doi.org/10.1111/j.1365-2141.1977.tb00640.x
  14. LappinTR, Maxwell AP, Johnston PG. EPO's alter ego: erythropoietin has multiple actions. Stem Cells. 2002;20(6):485-92. https://doi.org/10.1634/stemcells.20-6-485
  15. Park DW, Shin GJ, Lee WC. The effects of Bojungickitang on the inhibition of lipid accumulation of liver tissue in mouse induced hyperlipidemia. J. Korean Oriental internal medicine.1999;20(2):93-104.
  16. Cho CJ, Nam HI, Kim DW, Park YC,Lee JE, HanYJ et al.The chronic perennial rhitis sutterers evaluated through the eosinophil and subjects symptom numerical index and treated with Bojungickitang. J. Korean Oriental internal medicine.2005;26(2):467-74.
  17. Choi IS, Min SS, Kim JH, Seo SH, Park SE, Kim YK et al.A Clinical study of the patients in stroke treated with Bojungikki-tang and Bojungikki-tang-gamibang J. Korean Oriental internal medicine. 2004;25(3):388-97.
  18. Kim DW, Wu HT, Ha SK, Cho GC, Rhee SH, Han CH. A clinical process report on the patient of aplastic anemia treated with Bojoongikgibohyol-tang. J. Korean Oriental internal medicine. 2003;Autumn(2):238-45.
  19. Kim EG, Kim SK, ShinYS, Han JH, Lee JH. Aclinical report on iron deficiency anemia. J. Korean Oriental internal medicine. 2004;25(4):356-63.
  20. Park AM, Kim YC, Lee JH, Woo HJ. Effect of Jaukium-derivative on experimental aplastic anemia. Korean J.Oriental medicine. 2002; 25(1):133-46.
  21. Shin JW, Lee MM, Son JY, Lee NH, Cho CK,Chung WK et al.Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice. World J Gastroenterol. 2008;14(15): 2323-8. https://doi.org/10.3748/wjg.14.2323