The KSFM Journal of Fluid Machinery (한국유체기계학회 논문집)

Korean Society for Fluid machinery (한국유체기계학회)
권호 표지
DOI QR코드

DOI QR Code

Development of an Implantable Drug Infusion Pump for Pain Control in Cancer Patients

암 환자 통증 조절을 위한 이식형 약물 주입 펌프 개발

  • 백두진 (국립암센터 연구소 의공학연구과) ;
  • 박준우 (국립암센터 연구소 의공학연구과) ;
  • 홍소영 (국립암센터 연구소 의공학연구과) ;
  • 이철한 (국립암센터 연구소 의공학연구과) ;
  • 김광기 (국립암센터 연구소 의공학연구과) ;
  • 조영호 (국립암센터 연구소 의공학연구과) ;
  • 김대현 (국립암센터 부속병원 마취통증의학과)
  • Received : 2009.01.30
  • Accepted : 2009.05.25
  • Published : 2009.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

This paper presents a implantable intrathecal drug infusion pump for pain control in cancer patients. This device consists of micropump module, drug reservoir module and control module. The micropump module using cam-follower mechanism composed of small-sized four cams and four followers. Each followers is driven by a cam and liquid is discharged by a sequential reciprocal motion of the followers. The advantage of this structure is that it allows the pump to be clean and valveless. The drug reservoir module composed of drug chamber, gas chamber and diaphragm. The control module composed of battery, wireless communication unit and controller. To design a small-sized, low power pump some analysis were performed to determine the design parameters. To verify the feasibility of the experiment, a prototype was manufactured and its operating characteristics were investigated. Experimental results were in accordance with the expected results obtained from analysis.

Keywords

References

  1. S. Hong, J. Choi, J. W. Park, C. H. Lee, J. W. Shin, J. C. Lee and Y. H. Jo, 2005, 'Review: Implantable Intrathecal Drug Infusion System for the Control of Intractable Pain,' Proceedings of the 32th Korean Society of Medical and Biological Engineering Conference, CD.P-166
  2. William P. Van Antwerp, Susan M. McConnell, Peter C. Lord, 2001, Constant Flow Medication Infusion Pump, U.S.Patent 6,280,416 B1
  3. Steven R. Christenson, Reginald D. Robinson, James M. Haase, Manfred K. Luedi, 2003, 'Implantable Drug Infusion Device with Peristaltic Pump using Tube Guides,' U.S.Patent 6,626,867 B1
  4. Du-Jin Bach, Jun Woo Park, Duck Hee Lee, Chul Han Lee, Soyoung Hong and Yung Ho Jo, 2008, 'Micro Tube Pump for an Implantable Drug Infusion Device,' Journal of Fluid Machinery, Vol. 11, No. 1, pp. 40∼45 https://doi.org/10.5293/KFMA.2008.11.1.040
  5. James M. Olsen, Reginald D. Robinson, Chris Christiansen, Paul Kratoska, 2001, Overfill Protection System for Implantable Drug Delivery Devices, U.S.Patent 6,228,050 B1
  6. D. J. Bach, J. W. Park, S. Y. Hong, C. H. Lee and Y. H. Jo, 2007, 'Design of a Reservoir for an Implantable Infusion System,' Proceedings of the 36th Korean Society of Medical and Biological Engineering Conference, CD.P1-52
  7. J. W. Park, J. Choi, C. H. Lee, S. J. Song, S. Hong, J. C. Lee, Y. H. Kim and Y. H. Jo, 2005, 'Development of the Controller for the NCC Implantable Intrathecal Drug Pump,' Proceedings of the 33th Korean Society of Medical and Biological Engineering Conference, CD.P-137
  8. SynchroMed Infusion System Clinical Reference Guide for Pain Therapy, 2001, Medtronic Inc
  9. Arthur C. Guyton and John E. Hall, 2005, Textbook of Medical Physiology, Saunders Co

Cited by

  1. vol.13, pp.1, 2010, https://doi.org/10.5293/KFMA.2010.13.1.052