Advances in Traditional Medicine

  • 제9권2호
  • /
  • Pages.200-205
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  • 2009
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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Secondary metabolites (Triterpenes) from Couroupita guianensis

  • Begum, Rokeya (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka) ;
  • Rahman, Mohammad S (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka) ;
  • Chowdhury, A M Sarwaruddin (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka) ;
  • Hasan, Choudhury M (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka) ;
  • Rashid, Mohammad A (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka)
  • 발행 : 2009.06.30
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초록

The n-hexane and carbon tetrachloride soluble fractions of a methanolic extract of the stem bark of the Couroupita guianensis furnished three compounds, identified as $\beta$-amyrin (1), betulin-$3{\beta}$-caffeate (2) and lupeol-$3{\beta}$-caffeate (3). The structures of the isolated compounds were deduced by extensive spectroscopic analysis as well as by comparison with published values. Compounds 1-3 were subjected to antioxidant screening through free radical scavenging activity by DPPH (1,1-diphenyl-2-picrylhydrazyl), where compound 2 showed moderate antioxidant activity with $IC_{50}$ value $108.0{\mu}g/ml$.

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참고문헌

  1. Alvarenga N, Ferro EA. (2000) A new lupane caffeoyl ester from Hippocratea volubilis. Fitoterapia 71, 719-721 https://doi.org/10.1016/S0367-326X(00)00217-3
  2. Anjaneyulu, ASRSS. (1998) A new ketosteroid from the bark of Couroupita guianensis Aubl. Indian J. Chem. 37, 382-386
  3. Bergman J, Lindstrom J, Tilstam U. (1985) The structure and properties of some indolic constituents in Couroupita guianensis aubl. Tetrahedron 41, 2879-2881 https://doi.org/10.1016/S0040-4020(01)96609-8
  4. Chen B, Duan H, Takaishi Y. (1999) Triterpene caffeoyl esters and diterpenes from Celastrus stephanotifolius. Phytochemistry 51, 683-687 https://doi.org/10.1016/S0031-9422(99)00079-5
  5. Chumkaew P, Kato S, Chantrapromma K. (2005) A New Triterpenoid Ester from the Fruits of Bruguiera parviflora. Chem. Pharm. Bull. 53, 95-96 https://doi.org/10.1248/cpb.53.95
  6. Dictionary of Natural Products on CD-ROM, version 9.2, Chapman & Hall, 2001
  7. Ercil D, Sakar MK, Olmo ED, Feliciano AS. (2004) Chemical Constituents of Linaria aucheri. Turkish J. Chem. 28, 133-139
  8. Haque AM. (1986) Plant names of Bangladesh. Bangladesh National Herbarium. Ministry of Environment and Forest, Dhaka, Bangladesh. p. 137, 214
  9. Khan MR, Kihara M, Omoloso AD. (2003) Antibiotic Activity of Couroupita guianensis. J. Herbs Spices Med. Plants 10, 95-108 https://doi.org/10.1300/J044v10n03_10
  10. Mahanto SB, Kundu AP. (1994) 13C NMR spectra of pentacyclic triterpenoids-acompilation and some salient features. Phytochemistry 37, 1517-1575 https://doi.org/10.1016/S0031-9422(00)89569-2
  11. Pan H, Lundgren LN, Andersson R. (1994) Triterpene caffeates from bark of Betula pubescens. Phytochemistry 37, 795-799 https://doi.org/10.1016/S0031-9422(00)90360-1
  12. Siddiqui S, Hafeez F, Begum S, Siddiqui BS. (1988) A new pentacyclic triterpene from the leaves of Nerium oleander. J. Nat. Prod. 51, 229-233 https://doi.org/10.1021/np50056a006
  13. Thanakijcharoenpath W, Theanphong O. (2007) Triterpenoids from the stem of Diospyros glandulosa. Thai J. Pharm. Sci. 31, 1-8
  14. Usher G. (1984) A dictionary of plants. CBS publishers and distributors, Delhi. p.180
  15. Vanwagenen BC, Larsen R, Cardellina, JH II, Randazzo D, Lidert ZC, Swithenbank C. (1993) Ulosantoin, a potent insecticide from the sponge Ulosa ruetzleri. J. Organic Chem. 58, 335-337 https://doi.org/10.1021/jo00054a013