Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Secondary metabolites (Triterpenes) from Couroupita guianensis

  • Begum, Rokeya (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka) ;
  • Rahman, Mohammad S (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka) ;
  • Chowdhury, A M Sarwaruddin (Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka) ;
  • Hasan, Choudhury M (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka) ;
  • Rashid, Mohammad A (Department of Applied Chemistry and Chemical Technology, Faculty of Engineering and Technology, University of Dhaka)
  • Published : 2009.06.30
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Abstract

The n-hexane and carbon tetrachloride soluble fractions of a methanolic extract of the stem bark of the Couroupita guianensis furnished three compounds, identified as $\beta$-amyrin (1), betulin-$3{\beta}$-caffeate (2) and lupeol-$3{\beta}$-caffeate (3). The structures of the isolated compounds were deduced by extensive spectroscopic analysis as well as by comparison with published values. Compounds 1-3 were subjected to antioxidant screening through free radical scavenging activity by DPPH (1,1-diphenyl-2-picrylhydrazyl), where compound 2 showed moderate antioxidant activity with $IC_{50}$ value $108.0{\mu}g/ml$.

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References

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