Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Analysis of Quinic Acid Derivatives on Seven Cultivars of the Lettuce (Lactuca sativa L.) and Peroxynitrite Scavenging Effect

상추 7 품종의 Quinic Acid 유도체 분석 및 Peroxynitrite 소거효과

  • Nugroho, Agung (Department of Pharmaceutical Engineering, Sangji University, Sangji University) ;
  • Jang, Suk-Woo (Highland Agriculture Research Center, Rural Development Administration) ;
  • Kim, Won-Bae (Highland Agriculture Research Center, Rural Development Administration) ;
  • Lee, Kang-Ro (Natural Products Laboratory College of Pharmacy, SungKyunKwan University) ;
  • Choi, Jae-Sue (Devision of Food Science and Biotechnology, Pukyong National University) ;
  • Park, Hee-Juhn (Department of Pharmaceutical Engineering, Sangji University, Sangji University)
  • Published : 2009.12.31
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Abstract

The compositional analysis and the peroxynitrite ($ONOO^-$) scavenging assay were undertaken to demonstrate beneficial dietary effect of lettuce (Lactuca sativa L., Compositae). Quinic acid derivatives of the seven cultivars were qualitatively and quantitatively analyzed by HPLC to lead to the finding of 3,4-di-O-caffeoyquinic acid and 3-O-p-coumaroylquinic acid and their contents ranged over 2.72-4.47 mg/g and 8.97-23.26 mg/g, respectively. A cultivar Hacheong had the highest quantity of quinic acid derivatives. The peroxynitrite scavenging effect of the five cultivars (Jangsu, Gosina 27, Gopung, Yeolpungjeogchima, and Mipungjeogchugmyeon) were ranged over 7.45-8.26${\mu}g$/ml as $IC_{50}s$ while those of Hacheong and Mihong had less effect ($IC_{50}$ >10 ${\mu}g$/ml).

Keywords

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