Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Minor Phenolic Constituents of the Anemarrhenae Rhizoma

  • Youn, Ui-Joung (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Lee, Ye-Seul (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Jeong, Ha-Na (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Nam, Joo-Won (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Lee, Yoo-Jin (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Son, Young-Min (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Hwang, Eun-Sook (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University) ;
  • Seo, Eun-Kyoung (Natural Product Chemistry Laboratory, College of Pharmacy and The Center for Cell Signaling & Drug Discovery Research, Ewha Womans University)
  • Published : 2009.12.31
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Abstract

A homoisoflavanone, 7,4'-dihydroxyhomoisoflavanone (1) and a flavanone, (2S)-7,4'-dihydroxy-5-methoxyflavanone (2), were isolated from the rhizomes of Anemarrhena asphodeloides, together with 4,4'-dihydroxychalcon (3), 2'-O-methylphlorethin (4), 1,3-bis-di-p-hydroxyphenyl-4-penten-1-one (5), and 2,4'-dihydroxy-4-methoxybenzophenone (6) on the basis of spectroscopic and physicochemical analyses including 1Dand 2D- NMR techniques as well as by comparison of their data with the published values. Compounds 1 - 4 were isolated for the first time from this plant source. Among isolates, compound 2 exhibited moderate inhibitory effect on the differentiation of pre-adipocyte 3T3-L1 cells.

Keywords

References

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