잡종견의 대동맥하 협착증을 동반한 팔로오증

Pentalogy of Fallot with Subaortic Stenosis in a Mixed Dog

  • 발행 : 2009.04.30

초록

암컷 잡종견(2년령, 체중 4.3 kg)이 운동불내성, 야행성 기침, 심잡음을 주증상으로 강원대학교 수의학부대학 부속동물병원에 내원하였다. 전수축기성 잡음이 양쪽에서 청진되었으며, 영상진단에서 대동맥 변위, 폐동맥협착, 심실중격결손, 심방중격결손, 양심실의 비대, 대동맥하협착이 확인되었다. 이러한 소견들을 바탕으로 대동맥하 협착증을 동반한 팔로오증으로 진단을 내렸다. 이는 국내에서 진단된 대동맥하 협착증과 복합된 팔로오증의 첫 번째 증례보고이다.

A 2-year-old female mixed dog(weighing 4.3 kg) was referred to the Veterinary Teaching Hospital, Kangwon National University, with primary complaints of exercise intolerance, nocturnal coughing and heart murmur. Diagnostic studies revealed bi-lateral holosystolic murmurs on phonocardiogram, over-riding aorta, pulmonic stenosis, ventricular septal defect, atrial septal defect, biventricular hypertrophy, and subaortic stenosis in diagnostic imaging studies. Based on the diagnostic findings, pentalogy of Fallot(POF) with subaortic stenosis(SAS) was tentatively diagnosed. This is the first case report of POF complicated with SAS in a dog in Korea.

키워드

참고문헌

  1. Bonagura JD, O'Grady MR, Herring DS. Echocardiography. Principles of interpretation. Vet Clin North Am Small Anim Pract 1985; 15: 1177-1194
  2. Dryzek P, Mazurek-Kula A, Moszura T, Sysa A. Right ventricle outflow tract stenting as a method of palliative treatment of severe tetralogy of fallot. Cardiol J 2008; 15: 376-379
  3. Hyun C, Park I-C. Congenital heart diseases in small animals: Part I. Genetic pathways and potential candidate genes. Vet J 2006; 171: 245-255 https://doi.org/10.1016/j.tvjl.2005.02.008
  4. Kubota H, Camilleri L, Legault B, Tahir A, Bailly P, Ruse F, Brazzalotto I, Lusson JR, de Riberolles C. Successful treatment of tetralogy of fallot with pulmonary atresia using a pulmonary homograft. Jpn Heart J 1997; 38: 869-875 https://doi.org/10.1536/ihj.38.869
  5. Moise NS. Doppler echocardiographic evaluation of congenital cardiac disease. An introduction. J Vet Intern Med 1989; 3: 195-207 https://doi.org/10.1111/j.1939-1676.1989.tb00858.x
  6. Park I-C, Lee H-S, Kim J-T, Lee J-S, Lee S-G, Hyun C. Pentalogy of fallot in a korean sapsaree dog. J Vet Med Sci 2007; 69: 73-76 https://doi.org/10.1292/jvms.69.73
  7. Patterson DF. Epidemiologic and genetic studies of congenital heart disease in the dog. Circ Res 1968; 23: 171-202 https://doi.org/10.1161/01.RES.23.2.171
  8. Patterson DF, Pyle RL, Van Mierop L, Melbin J, Olson M. Hereditary defects of the conotruncal septum in keeshond dogs: Pathologic and genetic studies. Am J Cardiol 1974; 34: 187-205 https://doi.org/10.1016/0002-9149(74)90198-2
  9. Pizzuti A, Sarkozy A, Newton AL, Conti E, Flex E, Digilio MC, Amati F, Gianni D, Tandoi C, Marino B, Crossley M, Dallapiccola B. Mutations of zfpm2/fog2 gene in sporadic cases of tetralogy of fallot. Hum Mutat 2003; 22: 372-377 https://doi.org/10.1002/humu.10261
  10. Tchervenkov CI, Hill S, Del Duca D, Korkola S. Surgical repair of atrioventricular septal defect with common atrioventricular junction when associated with tetralogy of fallot or double outlet right ventricle. Cardiol Young 2006; 16 Suppl 3, 59-64 https://doi.org/10.1017/S1047951106000771
  11. Werner P, Raducha MG, Prociuk U, Ostrander EA, Spielman RS, Kirkness EF, Patterson DF, Henthorn PS. The keeshond defect in cardiac conotruncal development is oligogenic. Hum Genet 2005; 116: 368-377 https://doi.org/10.1007/s00439-004-1242-3