References
- Sun, Y., Oberley, L. W., Elwell, J. H. & Sierra-Rivera, E. Antioxidant enzyme activities in normal and transformed mouse liver cells. Int J Cancer 44:1028-1033 (1989) https://doi.org/10.1002/ijc.2910440615
- Mitchell, J. R., Jollow, D. J., Potter, W. Z., Gillette, J. R. & Brodie, B. B. Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione. J Pharmacol Exp Ther 187:211-217 (1973)
- Pumford, N. R., Halmes, N. C. & Hinson, J. A. Covalent binding of xenobiotics to specific proteins in the liver. Drug Metab Rev 29:39-57 (1997) https://doi.org/10.3109/03602539709037572
- Ray, S. D. & Jena, N. A hepatotoxic dose of acetaminophen modulates expression of BCL-2, BCL-X (L), and BCL-X(S) during apoptotic and necrotic death of mouse liver cells in vivo. Arch Toxicol 73:594-606 (2000) https://doi.org/10.1007/s002040050013
- Gibson, J. D., Pumford, N. R., Samokyszyn, V. M. & Hinson, J. A. Mechanism of acetaminophen-induced hepatotoxicity: covalent binding versus oxidative stress. Chem Res Toxicol 9:580-585 (1996) https://doi.org/10.1021/tx950153d
- Adamson, G. M. & Harman, A.W. Oxidative stress in cultured hepatocytes exposed to acetaminophen. Biochem Pharmacol 45:2289-2294 (1993) https://doi.org/10.1016/0006-2952(93)90201-7
- Burcham, P. C. & Harman, A. W. Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes. J Biol Chem 266:5049-5054 (1991)
- Brown, P. O. & Botstein, D. Exploring the new world of the genome with DNA microarrays. Nat Genet 21: 33-37 (1999) https://doi.org/10.1038/4462
- Young, R. R. Genetix toxicology: Web resources. Toxicology 173:103-121 (2002) https://doi.org/10.1016/S0300-483X(02)00026-4
- Kim, J. H. et al. Toxicogenomics study on TK6 human lymphoblast cells treated with mitomycin C. Mol Cell Toxicol 3:165-171 (2007)
- Kim, J. Y. et al. Identification of potential biomarkers of genotoxicity and carcinogenicity in L5178Y mouse lymphoma cells by cDNA microarray analysis. Environ Mol Mutagen 45:80-89 (2005) https://doi.org/10.1002/em.20077
- Lee, E. M. et al. Genetic toxicity test of o-Nitrotoluene by ames, micronucleus, comet assays and microarray analysis. Mol Cell Toxicol 3:107-112 (2007)
- Lee, M. et al. cDNA microarray gene expression profiling of hydroxyurea, paclitaxel, and p-anisidine, genotoxic compounds with differing tumorigenicity results. Environ Mol Mutagen 42:91-97 (2003) https://doi.org/10.1002/em.10177
- Lee, W. S. et al. Genetic toxicity test of 8-hydroxyquinoline by ames, micronucleus, comet assays and microarray analysis. Mol Cell Toxicol 3:90-97 (2007)
- Heinloth, A. N. et al. Gene expression profiling of rat livers reveals indicators of potential adverse effects. Toxicol Sci 80:193-202 (2004) https://doi.org/10.1093/toxsci/kfh145
- Reilly, T. P. et al. Expression profiling of acetaminophen liver toxicity in mice using microarray technology. Biochem Biophys Res Commun 282: 321-328 (2001) https://doi.org/10.1006/bbrc.2001.4576
- Suh, S. K. et al. Gene expression profiling of acetaminophen induced hepatotoxicity in mice. Mol Cell Toxicol 2:246-243 (2006)
- Arnaiz, S. L., Llesuy, S., Cutrin, J. C. & Boveris, A. Oxidative stress by acute acetaminophen administration in mouse liver. Free Radic Biol Med 19:303-310 (1995) https://doi.org/10.1016/0891-5849(95)00023-Q
- Reid, A. B., Kurten, R. C., McCullough, S. S., Brock, R. W. & Hinson, J. A. Mechanisms of acetaminopheninduced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes. J Pharmacol Exp Ther 312: 509-516 (2005) https://doi.org/10.1124/jpet.104.075945
- Vasiliou, V., Buetler, T., Eaton, D. L. & Nebert, D.W. Comparison of oxidative stress response parameters in newborn mouse liver versus simian virus 40 (SV40)-transformed hepatocyte cell lines. Biochem Pharmacol 59:703-712 (2000) https://doi.org/10.1016/S0006-2952(99)00360-3
- Larson, A. M. et al. Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study. Hepatology 42:1364-1372 (2005) https://doi.org/10.1002/hep.20948
- Cohen, S. D. et al. Selective protein covalent binding and target organ toxicity. Toxicol Appl Pharmacol 143:1-12 (1997) https://doi.org/10.1006/taap.1996.8074
- Mirochnitchenko, O. et al. Acetaminophen Toxicity. Opposite effects of two forms of glutathione peroxidase. J Biol Chem 274:10349-10355 (1999) https://doi.org/10.1074/jbc.274.15.10349
- Canales, R. D. et al. Evaluation of DNA microarray results with quantitative gene expression platforms. Nat Biotechnol 24:1115-1122 (2006) https://doi.org/10.1038/nbt1236
- Rico-Bautista, E., lores-Morales, A. & Fernandez-Perez, L. Suppressor of cytokine signaling (SOCS) 2, a protein with multiple functions. Cytokine Growth Factor Rev 17:431-439 (2006) https://doi.org/10.1016/j.cytogfr.2006.09.008
- Tanaka, S. et al. Grb7 signal transduction protein mediates metastatic progression of esophageal carcinoma. J Cell Physiol 183:411-415 (2000) https://doi.org/10.1002/(SICI)1097-4652(200006)183:3<411::AID-JCP14>3.0.CO;2-Z
- Crabbe, J. C. et al. Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors. Nat Genet 14:98-101 (1996) https://doi.org/10.1038/ng0996-98
- Baurain, D., Dinant, M., Coosemans, N. & Matagne, R. F. Regulation of the alternative oxidase Aox1 gene in Chlamydomonas reinhardtii. Role of the nitrogen source on the expression of a reporter gene under the control of the Aox1 promoter. Plant Physiol 131:1418- 1430 (2003) https://doi.org/10.1104/pp.013409
- Villeneuve, D. J. et al. cDNA microarray analysis of isogenic paclitaxel- and doxorubicin-resistant breast tumor cell lines reveals distinct drug-specific genetic signatures of resistance. Breast Cancer Res Treat 96: 17-39 (2006) https://doi.org/10.1007/s10549-005-9026-6
- Liu, S. H. et al. Down-regulation of annexin A10 in hepatocellular carcinoma is associated with vascular invasion, early recurrence, and poor prognosis in synergy with p53 mutation. Am J Pathol 160:1831-1837 (2002) https://doi.org/10.1016/S0002-9440(10)61129-7
- Keyse, S. M. & Emslie, E. A. Oxidative stress and heat shock induce a human gene encoding a proteintyrosine phosphatase. Nature 359:644-647 (1992) https://doi.org/10.1038/359644a0
- Zimmers, T. A. Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms. J Surg Res 130: 45-51 (2006) https://doi.org/10.1016/j.jss.2005.07.036
- Koizumi, H., Kartasova, T., Tanaka, H., Ohkawara, A. & Kuroki, T. Differentiation-associated localization of small proline-rich protein in normal and diseased human skin. Br J Dermatol 134:686-692 (1996) https://doi.org/10.1111/j.1365-2133.1996.tb06971.x
- Belperio, J. A. et al. The role of the Th2 CC chemokine ligand CCL17 in pulmonary fibrosis. J Immunol 173:4692-4698 (2004) https://doi.org/10.4049/jimmunol.173.7.4692
- Turnley, A. M. Role of SOCS2 in growth hormone actions. Trends Endocrinol Metab 16:53-58 (2005) https://doi.org/10.1016/j.tem.2005.01.006
- Hirabayashi, S. et al. JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol 23:4267-4282 (2003) https://doi.org/10.1128/MCB.23.12.4267-4282.2003
- Fielden, M. R. & Zacharewski, T. R. Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology. Toxicol Sci 60:6-10 (2001) https://doi.org/10.1093/toxsci/60.1.6
- Cabibbo, A., Consalez, G. G., Sardella, M., Sitia, R. & Rubartelli, A. Changes in gene expression during growth arrest of hepG2 hepatoma cells induced by reducing agents or TGBb1. Oncogene 16:2935-2943 (1998) https://doi.org/10.1038/sj.onc.1201825
- Kim, B. H. et al. Expression profiling of actaminophen liver toxicity in mice using microarray technology. International symposium of the Korean society of toxicogenomics and toxicoproteomics. P-008, 111 (2004)