Biomedical Science Letters (대한의생명과학회지)

The Korean Society for Biomedical Laboratory Sciences (대한의생명과학회)
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Histological Change and Collagen Formation on Laser Wounded Rat using 808 nm Diode Laser and $CO_2$ Laser

  • Chung, Phil-Sang (Department of Otolaryngology-Head & Neck Surgery, Dankook University) ;
  • Shin, Jang-In (Medical Laser and Device Research Center, Dankook University) ;
  • Chang, So-Young (Medical Laser and Device Research Center, Dankook University) ;
  • Ahn, Jin-Chul (Medical Laser and Device Research Center, Dankook University)
  • ;
  • ;
  • ;
  • 안진철 (단국대학교 의과대학 의학레이저 연구센터)
  • Published : 2009.03.31
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Abstract

Lasers are necessity in our life related to the fields of medicine and cosmetic surgery. With 808 nm diode laser and $CO_2$ laser, we made some wounds on a dorsum of rat by laser irradiation. All of irradiations shows thermal effects on the whole region of skin tissues. They make wound damage depending on laser power and irradiation time. Because a collagen is plays an important role in tissue repair, we studied collagen accumulation in wound tissue. For wound healing, collagen accumulation was found in the near region of damage in epidermis and dermis layer of the rat skin. In case of the quantitative analysis of collagen in wound tissue, the amount of collagen in wound tissue by $CO_2$ laser irradiation is higher than that of 808 nm diode laser irradiation. And re-epithelialization was significantly faster in wound by $CO_2$ laser irradiation compared with that of 808 nm diode laser irradiation.

Keywords

References

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