DOI QR코드

DOI QR Code

A Nationwide Survey on the Prevalence of Intestinal Parasitic Infections in the Republic of Korea, 2004

  • Kim, Tong-Soo (Department of Malaria and Parasitic diseases, National Institute of Health) ;
  • Cho, Shin-Hyeong (Department of Malaria and Parasitic diseases, National Institute of Health) ;
  • Huh, Sun (Department of Parasitology, Hallym University College of Medicine) ;
  • Kong, Yoon (Department of Molecular parasitology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine) ;
  • Sohn, Woon-Mok (Department of Parasitology, Institute of Health Sciences, Gyeongsang National University College of Medicine) ;
  • Hwang, Seung-Sik (Department of Social and Preventive Medicine, Inha University School of Medicine) ;
  • Chai, Jong-Yil (Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine and Institute of Endemic Diseases, Seoul National University Medical Research Center) ;
  • Lee, Soon-Hyung (Korea Association of Health Promotion) ;
  • Park, Yun-Kyu (Department of Parasitology, Inha University School of Medicine) ;
  • Oh, Dae-Kyu (Centers for Disease Control and Prevention) ;
  • Lee, Jong-Koo (Centers for Disease Control and Prevention) ;
  • Working Groups in National Institute of Health, Working Groups in National Institute of Health (Working Groups in National Institute of Health) ;
  • Korea Association of Health Promotion, Korea Association of Health Promotion (Korea Association of Health Promotion)
  • 발행 : 2009.03.31

초록

National surveys on the prevalence of intestinal parasitic infections have been carried out every 5-7 years since 1971 in the Republic of Korea in order to establish control measures. The present nationwide survey was conducted from June to December 2004. The 10% population sampling data of Population and Housing Census by the Korean government in 2000 was used as the survey population. One sample was selected randomly from each of the 22,858 registered subjects, and a total of 20,541 people were ultimately included in this survey. Fecal examinations were performed by the cellophane thick smear and saturated brine flotation techniques. Pinworm infection was examined by cello-tape anal swab method. This survey also included a questionnaire study for a socioeconomic analysis. The total helminth egg positive rate was 3.7%, and the estimated total positive number among nationwide people was 1,780,000. The rates in urban and rural areas were 3.1% and 6.8%, respectively. As the total egg positive rate in the 6th survey in 1997 was 2.4%, the present survey showed that there was a considerable degree of increase in the prevalence rate of intestinal parasitic infections over the 7-year period following the 6th survey. The largest increases occurred in the egg positive rates of Clonorchis sinensis and heterophyids including Metagonimus yokogawai.

키워드

참고문헌

  1. Seo BS, Rim HJ, Loh IK, Lee SH, Cho SY, Park SC, Bae JW, Kim JH, Lee JS, Koo BY, Kim KS. Study on the status of helminthic infections in Koreans. Korean J Parasitol 1969; 7: 53-70 https://doi.org/10.3347/kjp.1969.7.1.53
  2. Kim CH, Park CH, Kim HJ, Chun HB, Min HK, Koh TY, Soh CT. Prevalence of intestinal parasites in Korea. Korean J Parasitol 1971;9: 25-38 https://doi.org/10.3347/kjp.1971.9.1.25
  3. Ministry of Health and Welfare, Korea Association of Health Promotion. Prevalence of intestinal parasitic infection in Korea-the sixth and the 7th reports-. Seoul, Korea. 1997 (6th) & 2004 (7th)
  4. Kim BJ, Ock MS, Kim IS, Yeo UB. Infection status of Clonorchis sinensis in residents of Hamyang-gun, Gyeongsangnam-do, Korea. Korean J Parasitol 2002; 40: 191-193 https://doi.org/10.3347/kjp.2002.40.4.191
  5. Lee GS, Cho IS, Lee YH, Noh HJ, Shin DW, Lee SG, Lee TY. Epidemiological study of clonorchiasis and metagonimiasis along the Geum-gang (River) in Okcheon-gun (county), Korea. Korean J Parasitol 2002; 40: 9-16 https://doi.org/10.3347/kjp.2002.40.1.9
  6. Choi DW, Park SD, Kim JW, Ahn DH, Kim YM. Intestinal parasite survey of Kyungbook National University Hospital patients. Korean J Parasitol 1971; 9: 47-53 https://doi.org/10.3347/kjp.1971.9.2.47
  7. Min DY, Ahn MH, Kim KM, Kim CW. Intestinal parasite survey in Seoul by stool examination at Hanyang University Hospital. Korean J Parasitol 1986; 24: 209-212 https://doi.org/10.3347/kjp.1986.24.2.209
  8. Chai JY, Han ET, Park YK, Guk SM, Kim JL, Lee SH. High endemicity of Metagonimus yokogawai infection among residents of Samchokshi, Kangwon-do. Korean J Parasitol 2000; 38: 33-36 https://doi.org/10.3347/kjp.2000.38.1.33
  9. Kim CH, Na YE, Kim NM, Shin DW, Chang DY. Intestinal parasite and Clonorchis sinensis infection among the inhabitants in the upper stream of Taechong Dam, Kumgang (River). Korean J Parasitol 1994; 32: 207-214 https://doi.org/10.3347/kjp.1994.32.4.207
  10. Kim DG, Kim TS, Cho SH, Song HJ, Sohn WM. Heterophyid metacercarial infections in brackish water fishes from Jinju-man (Bay), Kyongsangnam-do, Korea. Korean J Parasitol 2006; 44: 7-13 https://doi.org/10.3347/kjp.2006.44.1.7
  11. Chai JY, Park JH, Han ET, Shin EH, Kim JL, Guk SM, Hong KS, Lee SH, Rim HJ. Prevalence of Heterophyes nocens and Pygydiopsis summa infections among residents of the western and southern coastal islands of the Republic of Korea. Am J Trop Med Hyg 2004; 71: 617-622
  12. Cochran WG. Sampling Techniques. John Wiley & Sons, Inc. 1977
  13. Newcombe RG. Two-sided confidence intervals for the single proportion:Comparison of seven methods. Statist Med 1998; 17:857-872 https://doi.org/10.1002/(SICI)1097-0258(19980430)17:8<857::AID-SIM777>3.0.CO;2-E
  14. Agresti A. An introduction to categorical data analysis. John Wiley & Sons, Inc. 1996
  15. Agresti A, Coull BA. Approximate is better than 'Exact' for interval estimation of Binomial proportions. Am Statist 1998; 52: 119-126 https://doi.org/10.2307/2685469
  16. SAS. SAS/STAT$^{\circledR}$ User’s Guide (version 6.4th ed.). Cary, NC. SAS Inst. Inc. 1989
  17. SPSS. User’s Guide (version 12.0.1). Chicago, Illinois USA. SPSS Inc. 1990
  18. Parrish RS, Ware GO, Field JE. Slope ratio assay using SAS. Proc. SAS User's Group Int 1980; pp 429-437
  19. Hong ST, Chai JY, Choi MH, Huh S, Rim HJ, Lee SH. A successful experience of soil-transmitted helminth control in the Republic of Korea. Korean J Parasitol 2006; 44: 177-185 https://doi.org/10.3347/kjp.2006.44.3.177
  20. Seo BS, Lee SH, Cho SY. An epidemiologic study on clonorchiasis and metagonimiasis in riverside areas in Korea. Korean J Parasitol 1981; 19: 137-150 https://doi.org/10.3347/kjp.1981.19.2.137
  21. Cho SH, Lee KY, Lee BC, Cho PY, Cheun HI, Hong ST, Sohn WM, Kim TS. Prevalence of clonorchiasis in southern endemic areas of Korea in 2006. Korean J Parasitol 2008; 46: 133-137 https://doi.org/10.3347/kjp.2008.46.3.133

피인용 문헌

  1. Functional Genes and Proteins of Clonorchis sinensis vol.47, pp.suppl, 2009, https://doi.org/10.3347/kjp.2009.47.s.s59
  2. Epidemiology of cholangiocarcinoma: An update focusing on risk factors vol.101, pp.3, 2009, https://doi.org/10.1111/j.1349-7006.2009.01458.x
  3. Intestinal Helminthic Infections Diagnosed by Colonoscopy in a Regional Hospital during 2001-2008 vol.48, pp.1, 2009, https://doi.org/10.3347/kjp.2010.48.1.75
  4. Analysis of Parasitic Diseases Diagnosed by Tissue Biopsy Specimens at KyungHee Medical Center (1984-2005) in Seoul, Korea vol.48, pp.1, 2009, https://doi.org/10.3347/kjp.2010.48.1.85
  5. Epidemiological Survey on the Infection of Intestinal Flukes in Residents of Muan-gun, Jeollanam-do, the Republic of Korea vol.48, pp.2, 2010, https://doi.org/10.3347/kjp.2010.48.2.133
  6. Descriptive Epidemiology of Cholangiocarcinoma and Clonorchiasis in Korea vol.25, pp.7, 2010, https://doi.org/10.3346/jkms.2010.25.7.1011
  7. Seroprevalence of Tissue Invading Parasitic Infections Diagnosed by ELISA in Korea vol.25, pp.9, 2010, https://doi.org/10.3346/jkms.2010.25.9.1272
  8. Prevalence and associated factors of intestinal parasitisation: a cross-sectional study among outpatients with gastrointestinal symptoms in Catalonia, Spain vol.108, pp.1, 2009, https://doi.org/10.1007/s00436-010-2044-2
  9. Population attributable fraction of infection-related cancers in Korea vol.22, pp.6, 2009, https://doi.org/10.1093/annonc/mdq592
  10. Tracing of the Bile-Chemotactic Migration of Juvenile Clonorchis sinensis in Rabbits by PET-CT vol.5, pp.12, 2009, https://doi.org/10.1371/journal.pntd.0001414
  11. Prevalence of Clonorchis sinensis Metacercariae in Freshwater Fish from Three Latitudinal Regions of the Korean Peninsula vol.49, pp.4, 2011, https://doi.org/10.3347/kjp.2011.49.4.385
  12. Multiple recombinant antigens of Clonorchis sinensis for serodiagnosis of human clonorchiasis vol.108, pp.5, 2009, https://doi.org/10.1007/s00436-010-2179-1
  13. A Case of Clonorchiasis with Focal Intrahepatic Duct Dilatation Mimicking an Intrahepatic Cholangiocarcinoma vol.44, pp.1, 2011, https://doi.org/10.5946/ce.2011.44.1.55
  14. The global epidemiology of clonorchiasis and its relation with cholangiocarcinoma vol.1, pp.1, 2009, https://doi.org/10.1186/2049-9957-1-4
  15. The characteristics of the expression of heat shock proteins and cox-2 in the liver of hamsters infected with Clonorchis sinensis, and the change of endocrine hormones and cytokines vol.59, pp.4, 2009, https://doi.org/10.14411/fp.2012.036
  16. Development and evaluation of loop-mediated isothermal amplification (LAMP) for rapid detection of Clonorchis sinensis from its first intermediate hosts, freshwater snails vol.140, pp.11, 2009, https://doi.org/10.1017/s0031182013000498
  17. Epidemiological profile of Clonorchis sinensis infection in one community, Guangdong, People’s Republic of China vol.6, pp.1, 2013, https://doi.org/10.1186/1756-3305-6-194
  18. Chemotherapeutic drugs for common parasitic diseases in Korea vol.56, pp.6, 2009, https://doi.org/10.5124/jkma.2013.56.6.513
  19. A Survey of Intestinal Parasite Infection during a 10-Year Period (2003-2012) vol.16, pp.3, 2009, https://doi.org/10.5145/acm.2013.16.3.134
  20. Global numbers of infection and disease burden of soil transmitted helminth infections in 2010 vol.7, pp.1, 2009, https://doi.org/10.1186/1756-3305-7-37
  21. Heavy Hymenolepis nana Infection Possibly Through Organic Foods: Report of a Case vol.52, pp.1, 2009, https://doi.org/10.3347/kjp.2014.52.1.85
  22. Prevalence and Risk Factors of Clonorchiasis among Residents of Riverside Areas in Muju-gun, Jeollabuk-do, Korea vol.52, pp.4, 2009, https://doi.org/10.3347/kjp.2014.52.4.391
  23. Prevalence of Zoonotic Trematode Metacercariae in Freshwater Fish from Gangwon-do, Korea vol.52, pp.4, 2009, https://doi.org/10.3347/kjp.2014.52.4.399
  24. Regulation of anti-inflammatory cytokines IL-10 and TGF-β in mouse dendritic cells through treatment with Clonorchis sinensis crude antigen vol.46, pp.1, 2009, https://doi.org/10.1038/emm.2013.144
  25. Parasitic Infections Based on 320 Clinical Samples Submitted to Hanyang University, Korea (2004-2011) vol.52, pp.2, 2009, https://doi.org/10.3347/kjp.2014.52.2.215
  26. Control of clonorchiasis in Korea: effectiveness of health education for community leaders and individuals in an endemic area vol.19, pp.9, 2009, https://doi.org/10.1111/tmi.12338
  27. Anomalous union of the pancreaticobiliary duct without choledochal cyst: is cholecystectomy alone sufficient? vol.399, pp.8, 2014, https://doi.org/10.1007/s00423-014-1223-5
  28. Risk factors for perihilar cholangiocarcinoma: A hospital‐based case–control study vol.35, pp.3, 2009, https://doi.org/10.1111/liv.12618
  29. Evaluation of Modified Formalin-Ether Concentration Method Using Para Tube in Clinical Settings vol.35, pp.4, 2015, https://doi.org/10.3343/alm.2015.35.4.445
  30. Rare cause of jaundice in a post liver transplant patient vol.17, pp.4, 2009, https://doi.org/10.1111/tid.12414
  31. Prevalence of Clonorchis sinensis Infection among Residents along 5 Major Rivers in the Republic of Korea vol.54, pp.2, 2009, https://doi.org/10.3347/kjp.2016.54.2.215
  32. Multiplex Real-Time PCR Assay Targeting Eight Parasites Customized to the Korean Population: Potential Use for Detection in Diarrheal Stool Samples from Gastroenteritis Patients vol.11, pp.11, 2009, https://doi.org/10.1371/journal.pone.0166957
  33. Prevalence and Related Factors of Clonorchiasis among Five Major Riverside Residents in South Korea vol.27, pp.4, 2009, https://doi.org/10.12799/jkachn.2016.27.4.346
  34. Diagnosis and Removal of Ascaris lumbricoides during Endoscopic Examination vol.70, pp.6, 2017, https://doi.org/10.4166/kjg.2017.70.6.304
  35. Identifying Helminth Infections via Routine Fecal Parasitological Examinations in Korea vol.97, pp.3, 2009, https://doi.org/10.4269/ajtmh.17-0084
  36. Epidemiological and Clinical Parameters Features of Patients with Clonorchiasis in the Geum River Basin, Republic of Korea vol.2017, pp.None, 2009, https://doi.org/10.1155/2017/7415301
  37. A new method for estimating the prevalence of clonorchiasis in Korea : A proposal to replace arbitrary riverside sampling vol.96, pp.13, 2009, https://doi.org/10.1097/md.0000000000006536
  38. Molecular and Structural Characterization of the Tegumental 20.6-kDa Protein in Clonorchis sinensis as a Potential Druggable Target vol.18, pp.3, 2009, https://doi.org/10.3390/ijms18030557
  39. Prevalence of Clonorchis sinensis Metacercariae in Fish from Water Systems of Seomjin-gang (River) vol.55, pp.3, 2009, https://doi.org/10.3347/kjp.2017.55.3.305
  40. Prevalence and Intensity of Clonorchis sinensis Metacercariae in Freshwater Fish from Wicheon Stream in Gunwi-gun, Gyeongsangbuk-do, Korea vol.56, pp.1, 2009, https://doi.org/10.3347/kjp.2018.56.1.41
  41. Trends in Gallbladder Cancer Incidence and Survival in Korea vol.50, pp.4, 2009, https://doi.org/10.4143/crt.2017.279
  42. Infections with Digenean Trematode Metacercariae in Two Invasive Alien Fish, Micropterus salmoides and Lepomis macrochirus, in Two Rivers in Chungcheongbuk-do, Republic of Korea vol.56, pp.5, 2009, https://doi.org/10.3347/kjp.2018.56.5.509
  43. Detection of Enterobius vermicularis in greater Berlin, 2007-2017: seasonality and increased frequency of detection vol.38, pp.4, 2019, https://doi.org/10.1007/s10096-019-03495-1
  44. Currently Available Monitoring and Surveillance Systems for Taenia spp., Echinococcus spp., Schistosoma spp., and Soil-Transmitted Helminths at the Control/Elimination Stage: A Systematic Review vol.9, pp.1, 2009, https://doi.org/10.3390/pathogens9010047
  45. 2세 남아에서 충체 배출로 발견된 회충증 1예 vol.27, pp.1, 2009, https://doi.org/10.14776/piv.2020.27.e1
  46. High endemicity of Clonorchis sinensis infection in Binyang County, southern China vol.14, pp.8, 2009, https://doi.org/10.1371/journal.pntd.0008540
  47. Prevalence of Clonorchis sinensis infection in fish in South‐East Asia: A systematic review and meta‐analysis vol.43, pp.11, 2009, https://doi.org/10.1111/jfd.13245
  48. Cluster of Parasite Infections by the Spatial Scan Analysis in Korea vol.58, pp.6, 2020, https://doi.org/10.3347/kjp.2020.58.6.603
  49. Severe hepatobiliary morbidity is associated with Clonorchis sinensis infection: The evidence from a cross-sectional community study vol.15, pp.1, 2009, https://doi.org/10.1371/journal.pntd.0009116
  50. Foodborne zoonotic parasites of the family Opisthorchiidae vol.135, pp.None, 2009, https://doi.org/10.1016/j.rvsc.2020.10.024
  51. Utility of an Automatic Vision-Based Examination System (AVE-562) for the Detection of Clonorchis sinensis Eggs in Stool vol.41, pp.2, 2009, https://doi.org/10.3343/alm.2021.41.2.221
  52. Novel mechanism of hepatobiliary system damage and immunoglobulin G4 elevation caused by Clonorchis sinensis infection vol.9, pp.23, 2009, https://doi.org/10.12998/wjcc.v9.i23.6639