Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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한약 복용 후 발생한 메트헤모글로빈혈증 1예

Methemoglobinemia development after ingestion of a chinese herbal medicine: A case report

  • 현세은 (포천중문의과대학교 소아과학교실) ;
  • 황필주 (포천중문의과대학교 소아과학교실) ;
  • 남경필 (서울대학교 건설환경공학부) ;
  • 유은경 (포천중문의과대학교 소아과학교실) ;
  • 한만용 (포천중문의과대학교 소아과학교실)
  • Hyun, Se Eun (Department of Pediatrics, Pochon Medical College, Bundang CHA Hopital) ;
  • Hwang, Pil Joo (Department of Pediatrics, Pochon Medical College, Bundang CHA Hopital) ;
  • Nam, Kyung Pil (Department of Civil and Environment Engineering, Seoul National University) ;
  • Yoo, Eun Gyong (Department of Pediatrics, Pochon Medical College, Bundang CHA Hopital) ;
  • Han, Man Yong (Department of Pediatrics, Pochon Medical College, Bundang CHA Hopital)
  • 투고 : 2008.08.18
  • 심사 : 2008.10.26
  • 발행 : 2009.03.15
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초록

8세 여아가 증상 발현 3일전부터 한약을 복용 후, 내원 20시간 전에 발생한 청색증과 호흡곤란을 주소로 응급실에 내원하였다. 내원 당시 메트헤모글로빈 수치가 23.7%로, 메트헤모글로빈혈증 진단 하에 methylene blue로 치료하였다. 한약 성분은 암모니아가 239.41 mg/L로 높게 측정되었다. 이에 한약 복용 후 발생한 메트헤모글로빈혈증 1예를 보고하고자 한다.

An 8-year-old girl visited the emergency room with perioral cyanosis and dyspnea, which had developed 20 hrs prior to the hospital visit. She had taken a Chinese herbal medication for 3 days prior to the onset of the symptoms. A co-oximeter examination revealed a methemoglobin level of 23.7%. An intravenous infusion of methylene blue was administered. Chemical analysis of the herbal medication revealed an ammonia (NH$_{3}$) level of 239.41 mg/L. More studies are needed on the correlation between methemoglobinemia and the components of Chinese herbal medicines.

키워드

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