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Treatment of Compensatory Hyperhidrosis with Botulinum Toxin A -A case report-

보튤리늄 독소를 이용한 보상성 다한증의 치료경험 -증례보고-

  • Shin, Sang Ho (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shin, Eun Young (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Du Hwan (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Suh, Jeong Hun (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Leem, Jung Gil (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shin, Jin Woo (Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 신상호 (울산대학교 의과대학 서울아산병원 마취통증의학교실) ;
  • 신은영 (울산대학교 의과대학 서울아산병원 마취통증의학교실) ;
  • 김두환 (울산대학교 의과대학 서울아산병원 마취통증의학교실) ;
  • 서정훈 (울산대학교 의과대학 서울아산병원 마취통증의학교실) ;
  • 임정길 (울산대학교 의과대학 서울아산병원 마취통증의학교실) ;
  • 신진우 (울산대학교 의과대학 서울아산병원 마취통증의학교실)
  • Received : 2009.07.16
  • Accepted : 2009.09.14
  • Published : 2009.12.01

Abstract

Conventional thoracoscopic sympathectomy is an effective method in treating palmar-axillary hyperhidrosis. However, this may result in a postoperatively compensatory hyperhidrosis. Conservative treatments of compensatory hyperhidrosis consist of aluminum chloride, anticholinergics, iontrophoresis, and botulinum toxin A injections. Surgical treatments in compensatory hyperhidrosis include excision of axillary tissue, liposuction, and thoracoscopic sympathectomy. Intradermal injection of botulinum toxin A has used to treat focal axillary or palmar hyperhidrosis. Botulinum toxin A bestows significant benefits with few side-effects and is well-tolerated, with beneficial results lasting from 4-16 months. We report a case illustrating the beneficial use of botulinum toxin A in a 25-year-old healthy male patient with compensatory sweating of the flank after thoracoscopic sympathectomy. Modified Minor's starch iodine test was used to allow accurate assess the impact of hyperhidrosis on the patient. In conclusion, Botulinum toxin type A is a valuable therapy for compensatory sweating after endoscopic thoracic sympathectomy.

Keywords

References

  1. Licht PB, Pilegaard HK: Severity of compensatory sweating after thoracoscopic sympathectomy. Ann Thorac Surg 2004;78: 427-31 https://doi.org/10.1016/j.athoracsur.2004.02.087
  2. Schick CH, Horbach T: Sequelae of endoscopic sympathetic block. Clin Auton Res 2003; 13(Suppl 1): 136-9
  3. Chiou TS: Chronological changes of postsympathectomy compensatory hyperhidrosis and recurrent sweating in patients with palmar hyperhidrosis. J Neurosurg Spine 2005; 2: 151-4 https://doi.org/10.3171/spi.2005.2.2.0151
  4. Lee SK, Kim YT: Practical botox bible in cosmetic fields. Seoul, Medical Pub-lishing Inc. 2003, pp 122-31
  5. Lowe N, Campanati A, Bodokh I, Cliff S, Jaen P, Kreyden O, et al: The place of botulinum toxin type A in the treatment of focal hyperhidrosis. Br J dermatol 2004; 151: 1115-22 https://doi.org/10.1111/j.1365-2133.2004.06317.x
  6. Bechara FG, Sand M, Moussa G, Sand D, Altmeyer P, Hoffmann K, et al: Treatment of unilateral compensatory sweating after endoscopical thoracic sympathectomy for general hyperhidrosis with botulinum toxin A. Dermatol Surg 2006; 32: 745-8 https://doi.org/10.1111/j.1524-4725.2006.32150.x
  7. Kux M: Thoracic endoscopic sympathectomy in palmar and axillary hyperhidrosis. Arch Surg 1978; 113: 264-6 https://doi.org/10.1001/archsurg.1978.01370150036005
  8. Atkins JL, Butler PE: Hyperhidrosis: a review of current management. Plast Reconstr Surg 2002; 110: 222-8 https://doi.org/10.1097/00006534-200207000-00039
  9. Baumgartner FJ, Bertin S, Konecny J: Superiority of thoracoscopic sympathectomy over medical management for the palmoplantar subset of severe hyperhidrosis. Ann Vasc Surg 2009; 23: 1-7 https://doi.org/10.1016/j.avsg.2008.04.014
  10. Rex LO, Drott C, Claes G, G$\ddot{o}$thberg G, Dalman P: The Boras experience of endoscopic thoracic sympathicotomy for palmar, axillary, facial hyperhidrosis and facial blushing. Eur J Surg Suppl 1998; 580: 23-6
  11. Rathinam S, Nanjaiah P, Sivalingam S, Rajesh PB: Excision of sympathetic ganglia and the rami communicantes with histological confirmation offers better early and late outcomes in video assisted thoracoscopic sympathectomy. J Cardiothorac Surg 2008; 3: 50 https://doi.org/10.1186/1749-8090-3-50
  12. Kim WJ, Yoon KB, Kim WO, Yoon DM, Jo KS: Treatment of secondary hyperhidrosis: a report of three cases. Korean J Pain 2004; 17: 307-11 https://doi.org/10.3344/jkps.2004.17.2.307
  13. Naumann M, Lowe NJ, Kumar CR, Hamm H: Botulinum toxin type A is a safe and effective treatment for axillary hyperhidrosis over 16 months: a prospective study. Arch Dermatol 2003; 139: 731-6 https://doi.org/10.1001/archderm.139.6.731
  14. Ram R, Lowe NJ, Yamauchi PS: Current and emerging therapeutic modalities for hyperhidrosis, part 2: moderately invasive and invasive procedures. Cutis 2007; 79: 281-8