Acknowledgement
Supported by : Korean Pediatric Society
References
- Crowther SD, Rees PJ. Current treatment of asthma--focus on leukotrienes. Expert Opin Pharmacother 2000;1:1021-40 https://doi.org/10.1517/14656566.1.5.1021
- Sayers I, Barton S, Rorke S, Sawyer J, Peng Q, Beghe B, et al. Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population. Clin Exp Allergy 2003;33:1103-10 https://doi.org/10.1046/j.1365-2222.2003.01733.x
- Bigby TD, Hodulik CR, Arden KC, Fu L. Molecular cloning of the human leukotriene C4 synthase gene and assignment to chromosome 5q35. Mol Med 1996;2:637-46
- Sanak M, Simon HU, Szczeklik A. Leukotriene C4 synthase promoter polymorphism and risk of aspirin-induced asthma. Lancet 1997;350:1599-600 https://doi.org/10.1016/S0140-6736(05)64015-9
- Cowburn AS, Sladek K, Soja J, Adamek L, Nizankowska E, Szczeklik A, et al. Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. J Clin Invest 1998; 101:834-46 https://doi.org/10.1172/JCI620
- Sayers I, Barton S, Rorke S, Beghe B, Hayward B, Van Eerdewegh P, et al. Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma. Thorax 2003;58:417-24 https://doi.org/10.1136/thorax.58.5.417
- Van Sambeek R, Stevenson DD, Baldasaro M, Lam BK, Zhao J, Yoshida S, et al. 5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. J Allergy Clin Immunol 2000;106:72-6 https://doi.org/10.1067/mai.2000.107603
- Kim HB, Lee SY, Shim JY, Kim JH, Kang MJ, Hong SJ. The leukotriene C4 synthase (A-444C) promoter polymorphism is associated with the severity of exercise-induced asthma in Korean children. J Allergy Clin Immunol 2006;117: 1191-2 https://doi.org/10.1016/j.jaci.2005.12.1361
- Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 1999;399:789-93 https://doi.org/10.1038/21658
- Choi JH, Park HS, Oh HB, Lee JH, Suh YJ, Park CS, et al. Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase. Hum Genet 2004; 114:337-44 https://doi.org/10.1007/s00439-004-1082-1
- Lee SY, Kim HB, Kim JH, Kim BS, Kang MJ, Jang SO, et al. Responsiveness to montelukast is associated with bronchial hyperresponsiveness and total immunoglobulin E but not polymorphisms in the leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes in Korean children with exercise-induced asthma (EIA). Clin Exp Allergy 2007;37: 1487-93
- Hao L, Sayers I, Cakebread JA, Barton SJ, Beghe B, Holgate ST, et al. The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma. Clin Exp Allergy 2006;36:735-41 https://doi.org/10.1111/j.1365-2222.2006.02511.x
- Arriba-Mendez S, Sanz C, Isidoro-Garcia M, Davild I, Laffond E, Horeno E, et al. 927T>C polymorphism of the cysteinyl-leukotriene type-1 receptor (CYSLTR1) gene in children with asthma and atopic dermatitis. Pediatr Allergy Immunol 2006;17:323-8 https://doi.org/10.1111/j.1399-3038.2006.00416.x
- Sanz C, Isidro-Garcia M, Davila I, Moreno E, Laffond E, Lorente F. Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma. J Investig Allergol Clin Immunol 2006;16:331-7
- Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis 1987;136:225-44
- Joseph-Bowen J, de Klerk N, Holt PG, Sly PD. Relationship of asthma, atopy, and bronchial responsiveness to serum eosinophil cationic proteins in early childhood. J Allergy Clin Immunol 2004;114:1040-5 https://doi.org/10.1016/j.jaci.2004.07.051
- Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, et al. Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 2000;161: 309-29 https://doi.org/10.1164/ajrccm.161.1.ats11-99
- Garcia-Martin E. Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms. Curr Drug Metab 2008;9:487-97 https://doi.org/10.2174/138920008784892155
- Sampson AP, Siddiqui S, Buchanan D, Howarth PH, Holgate ST, Holloway JW, et al. Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 2000;55 Suppl 2:S28-31
- Acevedo N, Vergara C, Mercado D, Jiménez S, Caraballo L. The A-444C polymorphism of leukotriene C4 synthase gene is associated with IgE antibodies to Dermatophagoides pteronyssinus in a Colombian population. J Allergy Clin Immunol 2007;119:505-7 https://doi.org/10.1016/j.jaci.2006.10.002
- Kedda MA, Shi J, Duffy D, Phelps S, Yang I, O'Hara K, et al. Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. J Allergy Clin Immunol 2004;113:889-95 https://doi.org/10.1016/j.jaci.2004.02.008
- Asano K, Shiomi T, Hasegawa N, Nakamura H, Kudo H, Matsuzaki T, et al. Leukotriene C4 synthase gene A(-444)C polymorphism and clinical response to a CYS-LT(1) antagonist, pranlukast, in Japanese patients with moderate asthma. Pharmacogenetics 2002;12:565-70 https://doi.org/10.1097/00008571-200210000-00009
- Zhang J, Migita O, Koga M, Shibasaki M, Arinami T, Noguchi E. Determination of structure and transcriptional regulation of CYSLTR1 and an association study with asthma and rhinitis. Pediatr Allergy Immunol 2006;17:242-9 https://doi.org/10.1111/j.1399-3038.2005.00347.x