DOI QR코드

DOI QR Code

Comparison of the Diagnostic Validity of Real and Absolute Skin Temperature Differences for Complex Regional Pain Syndrome

복합부위통증증후군 진단 시 좌우 체온 차이의 실제값과 절대값의 진단적 타당도 비교

  • Nahm, Francis Sahngun (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Lee, Pyung Bok (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Park, Soo Young (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Kim, Yong Chul (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine) ;
  • Lee, Sang Chul (Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine)
  • 남상건 (서울대학교 의과대학 마취통증의학교실) ;
  • 이평복 (서울대학교 의과대학 마취통증의학교실) ;
  • 박수영 (서울대학교 의과대학 마취통증의학교실) ;
  • 김용철 (서울대학교 의과대학 마취통증의학교실) ;
  • 이상철 (서울대학교 의과대학 마취통증의학교실)
  • Received : 2009.06.30
  • Accepted : 2009.07.23
  • Published : 2009.08.01

Abstract

Background: A skin temperature difference is one of the variables used in the diagnosis of complex regional pain syndrome. However, there have been no reports as to whether the real (${\Delta}T$) or absolute value ($|{\Delta}T|$) of skin temperature differences should be used in the diagnosis of complex regional pain syndrome. This study was conducted to compare the diagnostic validity of ${\Delta}T$ with $|{\Delta}T|$ for complex regional pain syndrome using receiver operating characteristic curves (ROC). Methods: Infrared thermographic images were obtained from the 144 patients who were suspected to have CRPS in a unilateral limb. After ${\Delta}T$ and $|{\Delta}T|$ calculation from the thermographic image, ROCs of ${\Delta}T$ and $|{\Delta}T|$ were developed, and the areas under the curve (AUC) for the ROC curves were compared. Results: AUCs of ${\Delta}T$ and $|{\Delta}T|$ were 0.520 and 0.746 respectively, this difference was statistically significant (P < 0.001). Conclusions: Absolute skin temperature difference shows greater validity in the diagnosis of CRPS than ${\Delta}T$. Therefore, $|{\Delta}T|$ is more useful when comparing the skin temperature of CRPS patients.

Keywords

References

  1. Driessens M, Dijs H, Verheyen G, Blockx P: What is reflex sympathetic dystrophy? Acta Orthop Belg 1999; 65: 202-17
  2. Stanton-Hicks M: Complex regional pain syndrome. Anesthesiol Clin North America 2003; 21: 733-44 https://doi.org/10.1016/S0889-8537(03)00084-1
  3. Harden RN, Bruehl S, Galer BS, Saltz S, Bertram M, Backonja M, et al: Complex regional pain syndrome: are the IASP diagnostic criteria valid and sufficiently comprehensive? Pain 1999; 83: 211-9 https://doi.org/10.1016/S0304-3959(99)00104-9
  4. Harden RN, Bruehl S, Stanton-Hicks M, Wilson PR: Proposed new diagnostic criteria for complex regional pain syndrome. Pain Med 2007; 8: 326-31 https://doi.org/10.1111/j.1526-4637.2006.00169.x
  5. Veldman PH, Reynen HM, Arntz IE, Goris RJ: Signs and symptoms of reflex sympathetic dystrophy: prospective study of 829 patients. Lancet 1993; 342: 1012-6 https://doi.org/10.1016/0140-6736(93)92877-V
  6. Bruehl S, Lubenow TR, Nath H, Ivankovich O: Validation of thermography in the diagnosis of reflex sympathetic dystrophy. Clin J Pain 1996; 12: 316-25 https://doi.org/10.1097/00002508-199612000-00011
  7. Birklein F, Riedl B, Claus D, Neund$\ddot{o}$orfer B: Pattern of autonomic dysfunction in time course of complex regional pain syndrome. Clin Auton Res 1998; 8: 79-85 https://doi.org/10.1007/BF02267817
  8. Wasner G, Schattschneider J, Baron R: Skin temperature side differences -- a diagnostic tool for CRPS? Pain 2002; 98: 19-26 https://doi.org/10.1016/S0304-3959(01)00470-5
  9. Uematsu S, Hendler N, Hungerford D, Long D, Ono N: Thermography and electromyography in the differential diagnosis of chronic pain syndromes and reflex sympathetic dystrophy. Electromyogr Clin Neurophysiol 1981; 21: 165-82
  10. Zweig MH, Campbell G: Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem 1993; 39: 561-77
  11. Park SH, Goo JM, Jo CH: Receiver operating characteristic (ROC) curve: practical review for radiologists. Korean J Radiol 2004; 5: 11-8 https://doi.org/10.3348/kjr.2004.5.1.11
  12. Park SH, Lee PB, Lim YH, Lee SY, Choi IY, Lee SJ, et al: The usefulness of three-phase bone scan and thermography for making the diagnosis of CRPS-I. Korean J Pain 2006; 19: 81-6 https://doi.org/10.3344/kjp.2006.19.1.81
  13. Low PA, Amadio PC, Wilson PR, McManis PG, Willner CL: Laboratory findings in reflex sympathetic dystrophy: a preliminary report. Clin J Pain 1994; 10: 235-9 https://doi.org/10.1097/00002508-199409000-00010
  14. Zyluk A: The natural history of post-traumatic reflex sympathetic dystrophy, J Hand Surg Br 1998; 23: 20-3
  15. Bruehl S, Harden RN, Galer BS, Saltz S, Backonja M, Stanton-Hicks M: Complex regional pain syndrome: are there distinct subtypes and sequential stages of the syndrome? Pain 2002; 95: 119-24 https://doi.org/10.1016/S0304-3959(01)00387-6
  16. Galer BS, Henderson J, Perander J, Jensen MP: Course of symptoms and quality of life measurement in complex regional pain syndrome: a pilot survey. J Pain Symptom Manage 2000; 20: 286-92 https://doi.org/10.1016/S0885-3924(00)00183-4

Cited by

  1. Interexaminer reliability of infrared thermography for the diagnosis of complex regional pain syndrome vol.19, pp.2, 2013, https://doi.org/10.1111/srt.12032
  2. Infrared Thermography in Pain Medicine vol.26, pp.3, 2013, https://doi.org/10.3344/kjp.2013.26.3.219
  3. Do Severity Score and Skin Temperature Asymmetry Correlate with the Subjective Pain Score in the Patients with Complex Regional Pain Syndrome? vol.27, pp.4, 2014, https://doi.org/10.3344/kjp.2014.27.4.339
  4. The quantitative sensory testing is an efficient objective method for assessment of nerve injury vol.37, pp.1, 2015, https://doi.org/10.1186/s40902-015-0013-5
  5. Perfusion index as a reliable parameter of vasomotor disturbance in complex regional pain syndrome vol.121, pp.5, 2018, https://doi.org/10.1016/j.bja.2018.07.020
  6. Thermal imaging ruled out as a supplementary assessment in patients with fibromyalgia: A cross-sectional study vol.16, pp.6, 2009, https://doi.org/10.1371/journal.pone.0253281